ALNYLAM PHARMACEUTICALS, INC.

ALNY

Form 4 • Statement of Changes in Beneficial Ownership

SEC Accession Number: 0001735276-26-000050
Filing date: Mar 4, 2026
Earliest execution date: Mar 2, 2026

Summary

Type

Sell

Net shares

+3,171

% of shares

9.48%

Amount (USD)

$523,583

Insider confidence score

92.5 out of 100

Positive

  • Huge buy (≥5% of shares)
  • Large buy amount ($250K+)

Stock transactions

Transaction 1

Security

Common Stock

Action

Grant

Date

2026-03-02

Code

A

Net shares

+4,769.0

Acquired/Disposed

Acquired

Shares Owned Before

33,435.0

Shares Owned After

38,204.0

Transaction 2

Security

Common Stock

Action

Sell

Date

2026-03-02

Code

S

Net shares

-47.0

Price per Share

$323.62

Amount (USD)

$15,210.14

Acquired/Disposed

Disposed

Shares Owned Before

38,204.0

Shares Owned After

38,157.0

Transaction 3

Security

Common Stock

Action

Sell

Date

2026-03-02

Code

S

Net shares

-90.0

Price per Share

$324.65

Amount (USD)

$29,218.50

Acquired/Disposed

Disposed

Shares Owned Before

38,157.0

Shares Owned After

38,067.0

Transaction 4

Security

Common Stock

Action

Sell

Date

2026-03-02

Code

S

Net shares

-258.0

Price per Share

$325.63

Amount (USD)

$84,012.54

Acquired/Disposed

Disposed

Shares Owned Before

38,067.0

Shares Owned After

37,809.0

Transaction 5

Security

Common Stock

Action

Sell

Date

2026-03-02

Code

S

Net shares

-392.0

Price per Share

$326.81

Amount (USD)

$128,109.52

Acquired/Disposed

Disposed

Shares Owned Before

37,809.0

Shares Owned After

37,417.0

Transaction 6

Security

Common Stock

Action

Sell

Date

2026-03-02

Code

S

Net shares

-329.0

Price per Share

$327.67

Amount (USD)

$107,803.43

Acquired/Disposed

Disposed

Shares Owned Before

37,417.0

Shares Owned After

37,088.0

Transaction 7

Security

Common Stock

Action

Sell

Date

2026-03-02

Code

S

Net shares

-100.0

Price per Share

$328.71

Amount (USD)

$32,871.00

Acquired/Disposed

Disposed

Shares Owned Before

37,088.0

Shares Owned After

36,988.0

Transaction 8

Security

Common Stock

Action

Sell

Date

2026-03-02

Code

S

Net shares

-170.0

Price per Share

$329.71

Amount (USD)

$56,050.70

Acquired/Disposed

Disposed

Shares Owned Before

36,988.0

Shares Owned After

36,818.0

Transaction 9

Security

Common Stock

Action

Sell

Date

2026-03-02

Code

S

Net shares

-81.0

Price per Share

$330.85

Amount (USD)

$26,798.85

Acquired/Disposed

Disposed

Shares Owned Before

36,818.0

Shares Owned After

36,737.0

Transaction 10

Security

Common Stock

Action

Sell

Date

2026-03-02

Code

S

Net shares

-94.0

Price per Share

$331.93

Amount (USD)

$31,201.42

Acquired/Disposed

Disposed

Shares Owned Before

36,737.0

Shares Owned After

36,643.0

Transaction 11

Security

Common Stock

Action

Sell

Date

2026-03-02

Code

S

Net shares

-37.0

Price per Share

$332.64

Amount (USD)

$12,307.68

Acquired/Disposed

Disposed

Shares Owned Before

36,643.0

Shares Owned After

36,606.0

Derivative Transactions

Transaction 1

Security

Stock Option (right to buy)

Action

Grant

Date

2026-03-02

Code

A

Net shares

+10,480.0

Acquired/Disposed

Acquired

Shares Owned Before

0.0

Shares Owned After

10,480.0

Filing's footnotes

1. These shares are represented by restricted stock units (RSUs) granted under the Second Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. The RSUs will vest over a three-year period, with one third vesting on each of the first, second and third anniversaries of the grant date, subject to the Reporting Persons continuous service with the Issuer as of each such vesting date.

2. Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the award agreement to cover minimum statutory tax withholding obligations.

3. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $323.16 to $324.15. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

4. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $324.20 to $325.20. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

5. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $325.21 to $326.21. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

6. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $326.23 to $327.23. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

7. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $327.24 to $328.24. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

8. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $328.28 to $329.26. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

9. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $329.29 to $330.29. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

10. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $330.30 to $331.30. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

11. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $331.32 to $332.31. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

12. The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $332.34 to $332.24. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

13. The stock option vests as to 25% of the shares on the first anniversary of the grant date and the remaining shares vest in equal installments at the end of each successive three-month period thereafter until the fourth anniversary of the grant date, subject to the Reporting Persons continuous service with the Issuer as of each such vesting date.

This page is for informational purposes only. While we strive for accuracy, the summary may contain inaccuracies or omissions. Please refer to the official SEC filing for authoritative information. Open the SEC filing.