2026Q1
| Insider | Role (last 12 mo) | Shares held | Filed at |
|---|---|---|---|
| Prescott Group Capital Management Llc | 10% Owner | 6,626,403 | Dec 9, 2016 |
| Frohlich Phil | 10% Owner | 6,626,403 | Dec 9, 2016 |
| Mpm Bioventures III Llc | 10% Owner | 2,428,171 | Nov 5, 2010 |
| Mpm Bioventures III Parallel Fund, L.P. | 10% Owner | 2,428,171 | Nov 5, 2010 |
| MPM BIOVENTURES III GMBH & CO. Beteiligungs KG | 10% Owner | 2,428,171 | Nov 5, 2010 |
| Exec date | Filing date | Insider | Role | Signal | Confidence | Shares | % of shares | Under plan? | Amount (USD) |
|---|---|---|---|---|---|---|---|---|---|
| Feb 26, 2026 | Feb 27, 2026 | Roberts M Scot | Chief Scientific Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 26, 2026 | Feb 27, 2026 | WEAVER GREGORY L | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 30, 2026 | Feb 3, 2026 | Roberts M Scot | Chief Scientific Officer | Sell | 56.3 | +379 | 0.12% | ✗ | $28.9K |
| Jan 30, 2026 | Feb 2, 2026 | Garg Vipin K | Director | Sell | 22.5 | -4,706 | -1.10% | ✗ | $65.1K |
| Jan 31, 2026 | Feb 2, 2026 | Jordt Raymond M | Chief Business Officer | Neutral | 85.0 | +4,571 | 6.97% | ✗ | - |
| Jan 27, 2026 | Jan 29, 2026 | Jordt Raymond M | Chief Business Officer | Sell | 26.3 | -4,229 | -6.06% | ✗ | $26.1K |
| Jan 27, 2026 | Jan 29, 2026 | Garg Vipin K | Director | Sell | 22.5 | -17,898 | -4.26% | ✗ | $110.6K |
| Jan 27, 2026 | Jan 29, 2026 | Roberts M Scot | Chief Scientific Officer | Sell | 26.3 | -4,748 | -4.74% | ✗ | $29.3K |
| Jan 25, 2026 | Jan 27, 2026 | Jordt Raymond M | Chief Business Officer | Sell | 26.3 | -3,855 | -6.67% | ✗ | $21.2K |
| Jan 25, 2026 | Jan 27, 2026 | Garg Vipin K | Director | Sell | 22.5 | -17,984 | -4.53% | ✗ | $98.9K |
| Jan 25, 2026 | Jan 27, 2026 | Roberts M Scot | Chief Scientific Officer | Sell | 26.3 | -4,373 | -4.93% | ✗ | $24.1K |
| Jan 8, 2026 | Jan 9, 2026 | Pisano Wayne | Director | Buy | 91.3 | +5,000 | 58.84% | ✗ | $20.4K |
| Jan 1, 2026 | Jan 5, 2026 | Jordt Raymond M | Chief Business Officer | Sell | 27.5 | -2,475 | -5.42% | ✗ | $8.9K |
| Jan 5, 2026 | Jan 5, 2026 | Sohn Catherine A. | Director | Buy | 90.0 | +500 | 50.00% | ✗ | $2.1K |
| Dec 29, 2025 | Dec 29, 2025 | Jorkasky Diane | Director | Buy | 90.0 | +527 | 100.00% | ✗ | $2K |
| Dec 23, 2025 | Dec 23, 2025 | GILL JOHN | Director | Buy | 95.0 | +12,500 | 100.00% | ✗ | $51.3K |
| Dec 22, 2025 | Dec 22, 2025 | Durso Jerome Benedict | Director | Buy | 95.0 | +12,500 | 100.00% | ✗ | $51.6K |
| Dec 1, 2025 | Dec 1, 2025 | Durso Jerome Benedict | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 11, 2025 | Nov 12, 2025 | WEAVER GREGORY L | CFO | Sell | 26.3 | -5,672 | -19.73% | ✗ | $24.3K |
| Oct 1, 2025 | Oct 3, 2025 | WEAVER GREGORY L | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Oct 1, 2025 | Oct 3, 2025 | Arbet-Engels Christophe | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Oct 3, 2025 | Arbet-Engels Christophe | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Sep 25, 2025 | Sep 29, 2025 | Sohn Catherine A. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 25, 2025 | Sep 29, 2025 | Durso Jerome Benedict | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 25, 2025 | Sep 29, 2025 | Lawver Teri L | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 25, 2025 | Sep 29, 2025 | Jorkasky Diane | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 6, 2022 | Sep 29, 2025 | GILL JOHN | Director | Neutral | 27.5 | -2,714 | -100.00% | ✗ | - |
| Sep 25, 2025 | Sep 29, 2025 | Schafer Klaus | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 25, 2025 | Sep 29, 2025 | SAYARE MITCHEL | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 25, 2025 | Sep 29, 2025 | Hodges Philip | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 25, 2025 | Sep 29, 2025 | Pisano Wayne | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 16, 2025 | Sep 17, 2025 | Richardson Linda M | Chief Commercial Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 17, 2025 | Richardson Linda M | Chief Commercial Officer | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jul 31, 2025 | Aug 4, 2025 | Jordt Raymond M | Chief Business Officer | Neutral | 82.5 | +1,368 | 3.92% | ✗ | - |
| Jul 31, 2025 | Aug 4, 2025 | Harris Matthew Scott | Chief Medical Officer | Neutral | 77.5 | +2,018 | 2.47% | ✗ | - |
| Jul 31, 2025 | Aug 4, 2025 | Roberts M Scot | Chief Scientific Officer | Neutral | 77.5 | +846 | 1.16% | ✗ | - |
| Mar 17, 2025 | Mar 18, 2025 | Sohn Catherine A. | Director | Buy | 90.0 | +1,000 | 100.00% | ✗ | $5.8K |
| Mar 13, 2025 | Mar 14, 2025 | WEAVER GREGORY L | CFO | Buy | 95.0 | +10,000 | 100.00% | ✗ | $52K |
| Mar 7, 2025 | Mar 11, 2025 | Harris Matthew Scott | Chief Medical Officer | Neutral | 27.5 | -67,787 | -45.30% | ✗ | - |
| Feb 24, 2025 | Feb 26, 2025 | Lawver Teri L | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 26, 2025 | Lawver Teri L | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Feb 24, 2025 | Feb 25, 2025 | Durso Jerome Benedict | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 25, 2025 | Durso Jerome Benedict | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Feb 6, 2025 | Feb 7, 2025 | Sohn Catherine A. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 30, 2025 | Feb 3, 2025 | Garg Vipin K | CEO | Sell | 22.5 | -23,109 | -1.66% | ✗ | $184.9K |
| Jan 30, 2025 | Feb 3, 2025 | Harris Matthew Scott | Chief Medical Officer | Sell | 22.5 | -6,085 | -1.97% | ✗ | $54.2K |
| Jan 31, 2025 | Feb 3, 2025 | Jordt Raymond M | Chief Business Officer | Neutral | 85.0 | +2,614 | 8.10% | ✗ | - |
| Jan 30, 2025 | Feb 3, 2025 | Roberts M Scot | Chief Scientific Officer | Sell | 26.3 | -3,642 | -1.36% | ✗ | $46.3K |
| Jan 25, 2025 | Jan 28, 2025 | Roberts M Scot | Chief Scientific Officer | Sell | 26.3 | -4,264 | -7.36% | ✗ | $29.8K |
| Jan 25, 2025 | Jan 28, 2025 | Jordt Raymond M | Chief Business Officer | Sell | 26.3 | -3,862 | -10.68% | ✗ | $27K |
| Jan 25, 2025 | Jan 28, 2025 | Harris Matthew Scott | Chief Medical Officer | Sell | 26.3 | -4,994 | -7.16% | ✗ | $34.9K |
| Jan 25, 2025 | Jan 28, 2025 | Garg Vipin K | CEO | Sell | 22.5 | -18,157 | -5.43% | ✗ | $126.7K |
| Jan 1, 2025 | Jan 3, 2025 | Jordt Raymond M | Chief Business Officer | Sell | 26.3 | -2,485 | -10.34% | ✗ | $17.9K |
| Nov 11, 2024 | Nov 12, 2024 | WEAVER GREGORY L | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 12, 2024 | WEAVER GREGORY L | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Sep 26, 2024 | Sep 30, 2024 | Pisano Wayne | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 26, 2024 | Sep 30, 2024 | Hodges Philip | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 26, 2024 | Sep 30, 2024 | SAYARE MITCHEL | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 26, 2024 | Sep 30, 2024 | Schafer Klaus | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 26, 2024 | Sep 30, 2024 | GILL JOHN | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 26, 2024 | Sep 30, 2024 | Jorkasky Diane | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 26, 2024 | Sep 30, 2024 | Sohn Catherine A. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Aug 19, 2024 | Aug 20, 2024 | Drutz David | Director | Sell | 22.5 | -16,011 | -14.11% | ✗ | $110.5K |
| Jul 31, 2024 | Aug 1, 2024 | Shutterly Andrew | CFO | Neutral | 90.0 | +1,259 | 12.45% | ✗ | - |
| Jul 31, 2024 | Aug 1, 2024 | Roberts M Scot | Chief Scientific Officer | Neutral | 77.5 | +650 | 1.52% | ✗ | - |
| Jul 31, 2024 | Aug 1, 2024 | Jordt Raymond M | Chief Business Officer | Neutral | 85.0 | +917 | 6.67% | ✗ | - |
| Jul 31, 2024 | Aug 1, 2024 | Harris Matthew Scott | Chief Medical Officer | Neutral | 82.5 | +1,486 | 2.77% | ✗ | - |
| Jul 1, 2024 | Shutterly Andrew | Officer | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Feb 1, 2024 | Feb 5, 2024 | Roberts M Scot | Chief Scientific Officer | Sell | 26.3 | -4,131 | -4.92% | ✗ | $39.5K |
| Feb 1, 2024 | Feb 5, 2024 | Harris Matthew Scott | Chief Medical Officer | Sell | 26.3 | -4,133 | -3.90% | ✗ | $39.5K |
| Feb 1, 2024 | Feb 5, 2024 | Garg Vipin K | CEO | Sell | 22.5 | -15,689 | -2.66% | ✗ | $150.3K |
| Jan 30, 2024 | Feb 1, 2024 | Roberts M Scot | Chief Scientific Officer | Sell | 91.3 | +3,151 | 10.60% | ✗ | $26.5K |
| Jan 31, 2024 | Feb 1, 2024 | Jordt Raymond M | Chief Business Officer | Neutral | 90.0 | +5,030 | 57.73% | ✗ | - |
| Jan 30, 2024 | Feb 1, 2024 | Harris Matthew Scott | Chief Medical Officer | Sell | 78.8 | +548 | 1.27% | ✗ | $26.5K |
| Jan 30, 2024 | Feb 1, 2024 | Garg Vipin K | CEO | Sell | 22.5 | -3,808 | -1.38% | ✗ | $114.6K |
| Jan 30, 2024 | Feb 1, 2024 | Eisenstadt Richard I | CFO | Sell | 86.3 | +2,446 | 5.75% | ✗ | $21.3K |
| Jan 25, 2024 | Jan 29, 2024 | Roberts M Scot | Chief Scientific Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 25, 2024 | Jan 29, 2024 | Jordt Raymond M | Chief Business Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 25, 2024 | Jan 29, 2024 | Harris Matthew Scott | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 25, 2024 | Jan 29, 2024 | Garg Vipin K | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 25, 2024 | Jan 29, 2024 | Eisenstadt Richard I | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 1, 2024 | Jan 4, 2024 | Jordt Raymond M | Chief Business Officer | Sell | 26.3 | -2,503 | -22.33% | ✗ | $28.2K |
| Dec 29, 2023 | Jan 2, 2024 | Eisenstadt Richard I | CFO | Sell | 26.3 | -3,044 | -8.38% | ✗ | $34.2K |
| Sep 28, 2023 | Sep 29, 2023 | Schafer Klaus | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 28, 2023 | Sep 29, 2023 | Drutz David | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 28, 2023 | Sep 29, 2023 | Hodges Philip | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 28, 2023 | Sep 29, 2023 | Sohn Catherine A. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 28, 2023 | Sep 29, 2023 | GILL JOHN | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 28, 2023 | Sep 29, 2023 | SAYARE MITCHEL | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 28, 2023 | Sep 29, 2023 | Jorkasky Diane | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 28, 2023 | Sep 29, 2023 | Pisano Wayne | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Aug 15, 2023 | Aug 15, 2023 | Drutz David | Director | Buy | 77.5 | +300 | 1.02% | ✗ | $862.5 |
| Jul 31, 2023 | Aug 2, 2023 | Garg Vipin K | CEO | Neutral | 55.0 | +126 | 0.05% | ✗ | - |
| Jul 31, 2023 | Aug 2, 2023 | Eisenstadt Richard I | CFO | Neutral | 85.0 | +1,825 | 8.29% | ✗ | - |
| Jul 31, 2023 | Aug 2, 2023 | Harris Matthew Scott | Chief Medical Officer | Neutral | 77.5 | +691 | 2.07% | ✗ | - |
| Jul 31, 2023 | Aug 2, 2023 | Roberts M Scot | Chief Scientific Officer | Neutral | 82.5 | +568 | 2.86% | ✗ | - |
| Jul 31, 2023 | Aug 2, 2023 | Jordt Raymond M | Chief Business Officer | Neutral | 90.0 | +1,832 | 100.00% | ✗ | - |
| Aug 12, 2022 | Jul 6, 2023 | GILL JOHN | Director | Sell | 26.3 | -2,714 | -49.48% | ✗ | $40.7K |
| Mar 23, 2023 | Mar 27, 2023 | Drutz David | Director | Buy | 91.3 | +9,000 | 43.94% | ✗ | $38.4K |
| Mar 23, 2023 | Mar 27, 2023 | Sohn Catherine A. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |