2026Q1
| Insider | Role (last 12 mo) | Shares held | Filed at |
|---|---|---|---|
| Topper James N | 10% Owner | 1,074,467 | Feb 6, 2020 |
| Frazier Life Sciences VIII, L.P. | 10% Owner | 1,074,467 | Feb 6, 2020 |
| Fhm Life Sciences VIII, L.P. | 10% Owner | 1,074,467 | Feb 6, 2020 |
| Fhm Life Sciences VIII, L.L.C. | 10% Owner | 1,074,467 | Feb 6, 2020 |
| Chaudhuri Bhaskar | Director | 921,372 | May 12, 2021 |
| Exec date | Filing date | Insider | Role | Signal | Confidence | Shares | % of shares | Under plan? | Amount (USD) |
|---|---|---|---|---|---|---|---|---|---|
| Mar 2, 2026 | Mar 4, 2026 | Leonard Keith R | Director | Sell | 10.0 | -39,272 | -62.19% | ✓ | $997.2K |
| Mar 2, 2026 | Mar 4, 2026 | Welgus Howard G. | Director | Sell | 20.0 | -10,000 | -16.74% | ✓ | $256.5K |
| Feb 27, 2026 | Mar 3, 2026 | Edwards Larry Todd | Officer | Sell | 95.0 | +26,313 | 17.68% | ✗ | $92.8K |
| Feb 27, 2026 | Mar 3, 2026 | Watanabe Todd | Officer | Sell | 92.5 | +64,651 | 6.77% | ✗ | $940.5K |
| Feb 27, 2026 | Mar 3, 2026 | Matsuda Masaru | Officer | Sell | 90.0 | +24,942 | 3.69% | ✓ | $313.9K |
| Feb 27, 2026 | Mar 3, 2026 | Vairavan Latha | CFO | Sell | 95.0 | +24,147 | 37.96% | ✗ | $71.8K |
| Aug 18, 2022 | Mar 3, 2026 | Burnett Patrick | Officer | Sell | 90.0 | +40,463 | 9.48% | ✗ | $158.3K |
| Feb 2, 2026 | Feb 4, 2026 | Matsuda Masaru | Officer | Sell | 8.8 | -40,638 | -26.98% | ✓ | $1M |
| Feb 2, 2026 | Feb 4, 2026 | Burnett Patrick | Officer | Sell | 25.0 | -13,469 | -14.31% | ✓ | $346.5K |
| Feb 2, 2026 | Feb 4, 2026 | Watanabe Todd | Officer | Sell | 40.0 | -19,833 | -2.04% | ✗ | $505.7K |
| Feb 2, 2026 | Feb 4, 2026 | Vairavan Latha | CFO | Sell | 46.3 | -1,320 | -2.03% | ✗ | $33.7K |
| Feb 2, 2026 | Feb 4, 2026 | Welgus Howard G. | Director | Sell | 25.0 | -10,000 | -14.34% | ✓ | $250.5K |
| Feb 2, 2026 | Feb 4, 2026 | Edwards Larry Todd | Officer | Sell | 42.5 | -2,052 | -1.36% | ✗ | $52.3K |
| Jan 5, 2026 | Jan 7, 2026 | Burnett Patrick | Officer | Sell | 42.5 | -2,490 | -2.58% | ✓ | $72.2K |
| Jan 2, 2026 | Jan 6, 2026 | Welgus Howard G. | Director | Sell | 25.0 | -10,000 | -12.54% | ✓ | $289.6K |
| Dec 31, 2025 | Jan 2, 2026 | Burnett Patrick | Officer | Sell | 46.3 | -1,697 | -1.73% | ✗ | $49.6K |
| Dec 15, 2025 | Dec 17, 2025 | Burnett Patrick | Officer | Sell | 22.5 | -11,500 | -10.47% | ✓ | $332.9K |
| Dec 4, 2025 | Dec 8, 2025 | Munshi Amit | Director | Neutral | 90.0 | +2,021 | 101.05% | ✗ | - |
| Dec 1, 2025 | Dec 3, 2025 | Matsuda Masaru | Officer | Sell | 45.0 | -1,657 | -1.09% | ✓ | $50.1K |
| Dec 1, 2025 | Dec 3, 2025 | Welgus Howard G. | Director | Sell | 22.5 | -10,000 | -11.14% | ✓ | $302.1K |
| Nov 24, 2025 | Nov 25, 2025 | LIN SUE-JEAN | Director | Sell | 20.0 | -25,272 | -48.59% | ✗ | $778K |
| Nov 21, 2025 | Nov 24, 2025 | Watanabe Todd | Officer | Sell | 36.3 | -50,000 | -2.75% | ✓ | $1.5M |
| Nov 19, 2025 | Nov 21, 2025 | Matsuda Masaru | Officer | Sell | 42.5 | -2,550 | -1.66% | ✗ | $72.1K |
| Nov 20, 2025 | Nov 21, 2025 | Gilbert Halley E | Director | Sell | 20.0 | -16,532 | -42.77% | ✗ | $455.4K |
| Nov 13, 2025 | Nov 17, 2025 | Krishnamohan Neha | Director | Sell | 7.5 | -40,504 | -64.67% | ✓ | $939.5K |
| Nov 13, 2025 | Nov 17, 2025 | Leonard Keith R | Director | Neutral | 27.5 | -4,312 | -15.30% | ✗ | - |
| Nov 6, 2025 | Nov 10, 2025 | Edwards Larry Todd | Officer | Sell | 20.0 | -29,131 | -16.24% | ✗ | $732.9K |
| Nov 6, 2025 | Nov 10, 2025 | Burnett Patrick | Officer | Sell | 22.5 | -17,250 | -14.93% | ✓ | $417.1K |
| Nov 3, 2025 | Nov 5, 2025 | Burnett Patrick | Officer | Sell | 32.5 | -6,486 | -6.19% | ✓ | $156.4K |
| Nov 3, 2025 | Nov 5, 2025 | Welgus Howard G. | Director | Sell | 22.5 | -10,000 | -10.03% | ✓ | $252.7K |
| Nov 3, 2025 | Nov 5, 2025 | Vairavan Latha | CFO | Sell | 52.5 | -88 | -0.14% | ✗ | $2.2K |
| Nov 3, 2025 | Nov 5, 2025 | Watanabe Todd | Officer | Sell | 40.0 | -11,547 | -1.11% | ✗ | $285.4K |
| Nov 3, 2025 | Nov 5, 2025 | Matsuda Masaru | Officer | Sell | 42.5 | -7,208 | -4.47% | ✗ | $178.2K |
| Oct 28, 2025 | Oct 30, 2025 | Watanabe Todd | Officer | Sell | 32.5 | -40,000 | -3.71% | ✓ | $1M |
| Oct 2, 2025 | Oct 6, 2025 | Edwards Larry Todd | Officer | Sell | 42.5 | -4,504 | -1.24% | ✗ | $90.3K |
| Oct 1, 2025 | Oct 3, 2025 | Watanabe Todd | Officer | Sell | 35.0 | -45,000 | -4.00% | ✓ | $884.6K |
| Oct 1, 2025 | Oct 3, 2025 | Welgus Howard G. | Director | Sell | 28.8 | -10,000 | -9.11% | ✓ | $189.2K |
| Sep 8, 2025 | Sep 10, 2025 | Watanabe Todd | Officer | Sell | 47.5 | -10,129 | -0.89% | ✓ | $177.6K |
| Sep 4, 2025 | Sep 8, 2025 | Matsuda Masaru | Officer | Sell | 17.5 | -36,130 | -18.31% | ✓ | $583.7K |
| Sep 2, 2025 | Sep 4, 2025 | Welgus Howard G. | Director | Sell | 28.8 | -10,000 | -9.07% | ✓ | $156.4K |
| Aug 19, 2025 | Aug 21, 2025 | Burnett Patrick | Officer | Sell | 37.5 | -4,188 | -3.84% | ✓ | $66.2K |
| Aug 8, 2025 | Aug 12, 2025 | Burnett Patrick | Officer | Sell | 37.5 | -3,847 | -3.41% | ✓ | $54K |
| Aug 4, 2025 | Aug 5, 2025 | Watanabe Todd | Officer | Sell | 42.5 | -11,547 | -1.01% | ✗ | $165.4K |
| Aug 4, 2025 | Aug 5, 2025 | Burnett Patrick | Officer | Sell | 46.3 | -2,622 | -2.27% | ✗ | $37.6K |
| Aug 4, 2025 | Aug 5, 2025 | Vairavan Latha | CFO | Sell | 52.5 | -89 | -0.14% | ✗ | $1.3K |
| Aug 4, 2025 | Aug 5, 2025 | Matsuda Masaru | Officer | Sell | 42.5 | -6,330 | -3.11% | ✗ | $90.7K |
| Aug 1, 2025 | Aug 5, 2025 | Welgus Howard G. | Director | Sell | 37.5 | -10,000 | -4.75% | ✓ | $143K |
| Jul 10, 2025 | Jul 14, 2025 | Burnett Patrick | Officer | Sell | 22.5 | -28,750 | -11.07% | ✓ | $432.7K |
| Jul 1, 2025 | Jul 2, 2025 | Welgus Howard G. | Director | Sell | 28.8 | -9,208 | -8.42% | ✓ | $127.4K |
| Jun 18, 2025 | Jun 20, 2025 | Welgus Howard G. | Director | Sell | 28.8 | -10,139 | -8.48% | ✓ | $135.6K |
| Jun 13, 2025 | Jun 17, 2025 | Heron Patrick J | Director | Buy | 48.8 | +2,646 | 0.03% | ✗ | $34.6K |
| Jun 12, 2025 | Jun 16, 2025 | LIN SUE-JEAN | Director | Neutral | 90.0 | +7,609 | 39.78% | ✗ | - |
| Jun 12, 2025 | Jun 16, 2025 | Welgus Howard G. | Director | Neutral | 85.0 | +7,609 | 6.80% | ✗ | - |
| Jun 12, 2025 | Jun 16, 2025 | Heron Patrick J | Director | Neutral | 55.0 | +7,609 | 0.09% | ✗ | - |
| Jun 12, 2025 | Jun 16, 2025 | Leonard Keith R | Director | Neutral | 90.0 | +7,609 | 36.98% | ✗ | - |
| Jun 12, 2025 | Jun 16, 2025 | Curran Terrie | Director | Neutral | 90.0 | +7,609 | 75.05% | ✗ | - |
| Jun 12, 2025 | Jun 16, 2025 | Krishnamohan Neha | Director | Neutral | 90.0 | +7,609 | 48.32% | ✗ | - |
| Jun 12, 2025 | Jun 16, 2025 | Gilbert Halley E | Director | Neutral | 90.0 | +7,609 | 40.42% | ✗ | - |
| Jun 12, 2025 | Jun 16, 2025 | CHAUDHURI BHASKAR | Director | Neutral | 67.5 | +7,609 | 0.84% | ✗ | - |
| Jun 10, 2025 | Jun 12, 2025 | Watanabe Todd Franklin | Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 4, 2025 | Jun 6, 2025 | Heron Patrick J | Director | Buy | 48.8 | +2,268 | 0.03% | ✗ | $30.2K |
| May 28, 2025 | May 29, 2025 | Matsuda Masaru | Officer | Sell | 48.8 | -1,800 | -0.88% | ✗ | $24.8K |
| May 21, 2025 | May 23, 2025 | Heron Patrick J | Director | Buy | 60.0 | +5,040 | 0.06% | ✗ | $68.8K |
| May 19, 2025 | May 20, 2025 | Edwards Larry Todd | Officer | Sell | 42.5 | -7,451 | -3.91% | ✗ | $104.8K |
| May 15, 2025 | May 19, 2025 | Heron Patrick J | Director | Buy | 48.8 | +2,520 | 0.03% | ✗ | $34.3K |
| May 13, 2025 | May 15, 2025 | Heron Patrick J | Director | Buy | 60.0 | +8,674 | 0.10% | ✗ | $119.4K |
| May 9, 2025 | May 13, 2025 | Heron Patrick J | Director | Buy | 60.0 | +6,300 | 0.07% | ✗ | $85.7K |
| May 8, 2025 | May 9, 2025 | Burnett Patrick | Officer | Sell | 37.5 | -3,871 | -3.24% | ✓ | $52.6K |
| May 6, 2025 | May 7, 2025 | Vairavan Latha | CFO | Neutral | 90.0 | +20,000 | 44.34% | ✗ | - |
| May 7, 2025 | Vairavan Latha | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| May 2, 2025 | May 5, 2025 | Matsuda Masaru | Officer | Sell | 42.5 | -5,030 | -2.40% | ✗ | $76.5K |
| May 2, 2025 | May 5, 2025 | Watanabe Todd Franklin | Officer | Sell | 45.0 | -11,448 | -0.99% | ✗ | $173.9K |
| May 2, 2025 | May 5, 2025 | Burnett Patrick | Officer | Sell | 46.3 | -2,597 | -2.13% | ✗ | $39.4K |
| May 1, 2025 | May 5, 2025 | Welgus Howard G. | Director | Sell | 28.8 | -10,000 | -8.20% | ✓ | $146.4K |
| Apr 1, 2025 | Apr 3, 2025 | Welgus Howard G. | Director | Sell | 28.8 | -10,000 | -7.58% | ✓ | $151.2K |
| Apr 2, 2025 | Apr 3, 2025 | Topper David Joseph | CFO | Sell | 42.5 | -9,600 | -4.99% | ✗ | $151.7K |
| Mar 24, 2025 | Mar 26, 2025 | Watanabe Todd Franklin | Officer | Sell | 48.8 | -3,671 | -0.32% | ✓ | $64.4K |
| Mar 17, 2025 | Mar 20, 2025 | Watanabe Todd Franklin | Officer | Sell | 53.8 | -1,200 | -0.10% | ✓ | $21.1K |
| Mar 13, 2025 | Mar 17, 2025 | Burnett Patrick | Officer | Sell | 22.5 | -61,403 | -14.37% | ✓ | $920.5K |
| Feb 28, 2025 | Mar 4, 2025 | Burnett Patrick | Officer | Sell | 91.3 | +51,227 | 44.60% | ✗ | $49.4K |
| Feb 28, 2025 | Mar 4, 2025 | Watanabe Todd Franklin | Officer | Sell | 97.5 | +125,985 | 12.17% | ✗ | $327K |
| Feb 28, 2025 | Mar 4, 2025 | Topper David Joseph | CFO | Neutral | 90.0 | +34,000 | 21.47% | ✗ | - |
| Mar 3, 2025 | Mar 4, 2025 | Welgus Howard G. | Director | Sell | 32.5 | -10,000 | -7.05% | ✓ | $130K |
| Feb 28, 2025 | Mar 4, 2025 | Edwards Larry Todd | Officer | Neutral | 90.0 | +55,000 | 40.57% | ✗ | - |
| Feb 28, 2025 | Mar 4, 2025 | Matsuda Masaru | Officer | Sell | 91.3 | +30,737 | 17.20% | ✗ | $42.5K |
| Feb 3, 2025 | Feb 4, 2025 | Matsuda Masaru | Officer | Sell | 42.5 | -8,338 | -4.46% | ✗ | $105.9K |
| Feb 3, 2025 | Feb 4, 2025 | Watanabe Todd Franklin | Officer | Sell | 42.5 | -19,301 | -1.83% | ✗ | $245.1K |
| Feb 3, 2025 | Feb 4, 2025 | Welgus Howard G. | Director | Sell | 32.5 | -10,000 | -6.58% | ✓ | $127.1K |
| Feb 3, 2025 | Feb 4, 2025 | Burnett Patrick | Officer | Sell | 42.5 | -12,116 | -9.54% | ✗ | $153.9K |
| Feb 3, 2025 | Feb 4, 2025 | Edwards Larry Todd | Officer | Sell | 46.3 | -2,173 | -1.58% | ✗ | $27.6K |
| Jan 2, 2025 | Jan 6, 2025 | Welgus Howard G. | Director | Sell | 32.5 | -10,000 | -6.17% | ✓ | $146.7K |
| Dec 31, 2024 | Dec 31, 2024 | Burnett Patrick | Officer | Sell | 46.3 | -1,691 | -1.31% | ✗ | $23.7K |
| Dec 20, 2024 | Dec 23, 2024 | Watanabe Todd Franklin | Officer | Sell | 45.0 | -15,000 | -1.40% | ✓ | $227.6K |
| Nov 30, 2024 | Dec 3, 2024 | Edwards Larry Todd | Officer | Buy | 67.5 | +1,093 | 0.80% | ✗ | $7.8K |
| May 31, 2024 | Dec 3, 2024 | Matsuda Masaru | Officer | Buy | 83.8 | +5,657 | 3.12% | ✗ | $18.5K |
| Dec 2, 2024 | Dec 3, 2024 | Welgus Howard G. | Director | Sell | 32.5 | -10,000 | -5.82% | ✓ | $125.1K |
| May 31, 2024 | Dec 3, 2024 | Watanabe Todd Franklin | Officer | Buy | 68.8 | +6,038 | 0.57% | ✗ | $21.3K |
| Nov 22, 2024 | Nov 26, 2024 | Burnett Patrick | Officer | Sell | 22.5 | -16,023 | -11.07% | ✗ | $162.5K |
| Nov 18, 2024 | Nov 19, 2024 | Matsuda Masaru | Officer | Sell | 78.8 | +3,100 | 1.74% | ✗ | $17.2K |
| Nov 14, 2024 | Nov 18, 2024 | Burnett Patrick | Officer | Sell | 20.0 | -69,226 | -15.21% | ✗ | $712.6K |