ARROWHEAD PHARMACEUTICALS, INC. (ARWR)

Latest Insider Confidence Score

2026Q1

44.4
Bearish

Company insider confidence (by quarter)

2009Q1 2026Q1

Largest shareholders

Insider Role (last 12 mo) Shares held Filed at
Anzalone Christopher Richard CEO 3,921,255 Apr 11, 2025
O'Brien Patrick COO 527,201 Jan 7, 2025
Stewart R Bruce — 511,500 Nov 12, 2009
Myszkowski Kenneth Allen CFO 455,433 Jan 7, 2025
Hamilton James C Chief Medical Officer 212,122 Oct 3, 2025

Recent buy/sell transactions

Exec date Filing date Insider Role Signal Confidence Shares % of shares Under plan? Amount (USD)
Jan 6, 2026 Jan 8, 2026 Hamilton James C Chief Medical Officer Neutral 90.0 +75,000 43.62% ✗ -
Jan 6, 2026 Jan 8, 2026 Apel Daniel Joseph CFO Neutral 90.0 +75,000 74.11% ✗ -
Jan 6, 2026 Jan 8, 2026 O'Brien Patrick COO Neutral 90.0 +72,500 15.27% ✗ -
Dec 31, 2025 Jan 5, 2026 O'Brien Patrick COO Sell 27.5 -52,293 -9.92% ✓ $3.1M
Jan 5, 2026 Jan 5, 2026 Hamilton James C Chief Medical Officer Sell 18.8 -40,164 -18.93% ✓ $2.5M
Jan 2, 2026 Jan 5, 2026 Anzalone Christopher Richard CEO Sell 48.8 -13,187 -0.35% ✓ $871.7K
Dec 29, 2025 Dec 30, 2025 Anzalone Christopher Richard CEO Sell 43.8 -51,726 -1.34% ✓ $3.6M
Dec 26, 2025 Dec 30, 2025 Ferrari Mauro Director Sell 28.8 -7,530 -9.83% ✓ $527.1K
Dec 19, 2025 Dec 23, 2025 Waddill William D. Director Sell 25.0 -8,367 -12.89% ✓ $566K
Dec 19, 2025 Dec 23, 2025 Vakiener Victoria Director Sell 15.0 -10,040 -21.94% ✓ $679.5K
Dec 19, 2025 Dec 23, 2025 Anzalone Christopher Richard CEO Sell 46.3 -26,031 -0.68% ✓ $1.8M
Dec 19, 2025 Dec 23, 2025 OLUKOTUN ADEOYE Y Director Sell 15.0 -10,000 -22.94% ✓ $676.6K
Dec 17, 2025 Dec 19, 2025 Anzalone Christopher Richard CEO Sell 16.3 -85,000 -2.17% ✗ $5.4M
Dec 16, 2025 Dec 18, 2025 Ferrari Mauro Director Neutral 90.0 +7,819 11.37% ✗ -
Dec 16, 2025 Dec 18, 2025 Lu Hongbo Director Neutral 90.0 +7,819 16.58% ✗ -
Dec 16, 2025 Dec 18, 2025 PERRY MICHAEL S Director Neutral 85.0 +7,819 6.78% ✗ -
Dec 16, 2025 Dec 18, 2025 Vakiener Victoria Director Neutral 90.0 +7,819 20.61% ✗ -
Dec 16, 2025 Dec 18, 2025 INGRAM DOUGLAS S Director Neutral 90.0 +7,819 20.36% ✗ -
Dec 16, 2025 Dec 18, 2025 OLUKOTUN ADEOYE Y Director Neutral 90.0 +7,819 21.85% ✗ -
Dec 16, 2025 Dec 18, 2025 Waddill William D. Director Neutral 90.0 +7,819 13.69% ✗ -
Dec 12, 2025 Dec 16, 2025 Anzalone Christopher Richard CEO Sell 40.0 -4,298 -0.11% ✗ $12.3M
Dec 5, 2025 Dec 9, 2025 PERRY MICHAEL S Director Sell 20.0 -16,250 -12.36% ✗ $991.7K
Nov 28, 2025 Dec 1, 2025 Ferrari Mauro Director Sell 20.0 -8,750 -11.29% ✗ $493.4K
Oct 1, 2025 Oct 3, 2025 Hamilton James C Chief Medical Officer Sell 26.3 -20,000 -8.62% ✓ $700K
Sep 12, 2025 Sep 16, 2025 Hamilton James C Chief Medical Officer Sell 30.0 -15,000 -6.07% ✓ $450K
Sep 2, 2025 Sep 4, 2025 Hamilton James C Chief Medical Officer Sell 30.0 -15,000 -5.72% ✓ $375K
Aug 13, 2025 Aug 15, 2025 Hamilton James C Chief Medical Officer Sell 37.5 -10,000 -3.67% ✓ $200K
Aug 12, 2025 Apel Daniel Joseph CFO Neutral 52.5 - 0.00% ✗ -
Apr 9, 2025 Apr 11, 2025 Anzalone Christopher Richard CEO Sell 17.5 -141,122 -3.47% ✗ $1.5M
Mar 13, 2025 Mar 17, 2025 Anzalone Christopher Richard CEO Sell 92.5 +288,575 7.65% ✗ $775K
Mar 3, 2025 Mar 5, 2025 Anzalone Christopher Richard CEO Sell 26.3 -300,000 -7.36% ✓ $5.3M
Feb 7, 2025 Feb 10, 2025 Anzalone Christopher Richard CEO Neutral 60.0 +9,550 0.25% ✗ -
Feb 6, 2025 Feb 7, 2025 INGRAM DOUGLAS S Director Neutral 90.0 +38,396 100.00% ✗ -
Feb 7, 2025 INGRAM DOUGLAS S Director Neutral 52.5 - 0.00% ✗ -
Jan 23, 2025 Jan 27, 2025 OLUKOTUN ADEOYE Y Director Sell 45.0 -959 -2.61% ✓ $20.1K
Jan 4, 2025 Jan 7, 2025 Hamilton James C Chief Discovery/Trans Medicine Sell 97.5 +67,271 32.84% ✓ $648.8K
Jan 4, 2025 Jan 7, 2025 O'Brien Patrick COO Sell 97.5 +62,816 13.53% ✓ $736.1K
Jan 4, 2025 Jan 7, 2025 Myszkowski Kenneth Allen CFO Sell 97.5 +54,833 13.69% ✓ $893.1K
Jan 2, 2025 Jan 6, 2025 Anzalone Christopher Richard CEO Sell 48.8 -11,520 -0.31% ✓ $219.5K
Dec 27, 2024 Dec 30, 2024 OLUKOTUN ADEOYE Y Director Sell 32.5 -2,850 -7.20% ✓ $57K
Dec 23, 2024 Dec 23, 2024 Anzalone Christopher Richard CEO Sell 48.8 -12,563 -0.33% ✓ $246.1K
Dec 18, 2024 Dec 20, 2024 Vakiener Victoria Director Neutral 90.0 +16,733 78.89% ✗ -
Dec 18, 2024 Dec 20, 2024 OLUKOTUN ADEOYE Y Director Neutral 90.0 +16,733 73.21% ✗ -
Dec 18, 2024 Dec 20, 2024 Waddill William D. Director Neutral 90.0 +16,733 41.44% ✗ -
Dec 18, 2024 Dec 20, 2024 Ferrari Mauro Director Neutral 90.0 +16,733 27.53% ✗ -
Dec 18, 2024 Dec 20, 2024 PERRY MICHAEL S Director Neutral 90.0 +16,733 14.58% ✗ -
Dec 18, 2024 Dec 20, 2024 Lu Hongbo Director Neutral 90.0 +16,733 54.99% ✗ -
Dec 18, 2024 Dec 20, 2024 Anzalone Christopher Richard CEO Sell 85.0 +73,288 1.97% ✓ $567.5K
Dec 16, 2024 Dec 18, 2024 Waddill William D. Director Sell 20.0 -7,495 -15.66% ✓ $164.7K
Dec 16, 2024 Dec 18, 2024 GIVEN DOUGLAS B Director Sell 37.5 -5,547 -4.28% ✓ $121.6K
Dec 16, 2024 Dec 18, 2024 Vakiener Victoria Director Sell 10.0 -8,994 -29.78% ✓ $197.1K
Mar 22, 2024 Nov 15, 2024 Lu Hongbo Director Buy 22.5 -3,250 -8.26% ✗ $62.2K
Jul 2, 2024 Jul 3, 2024 Oliver Tracie Chief Commercial Officer Sell 32.5 -9,394 -6.88% ✓ $237.5K
May 2, 2024 May 6, 2024 Vakiener Victoria Director Sell 36.3 -1,799 -5.62% ✓ $41.9K
Apr 1, 2024 Apr 3, 2024 Hamilton James C Chief Discovery/Trans Medicine Sell 22.5 -6,000 -2.85% ✗ $168.2K
Mar 18, 2024 Mar 20, 2024 Lu Hongbo Director Buy 90.0 +3,000 9.78% ✗ $83K
Mar 18, 2024 Lu Hongbo Director Neutral 52.5 - 0.00% ✗ -
Mar 6, 2024 Mar 8, 2024 Myszkowski Kenneth Allen CFO Sell 17.5 -40,000 -9.08% ✗ $1.4M
Jan 31, 2024 Feb 2, 2024 Anzalone Christopher Richard CEO Sell 40.0 -57,499 -1.52% ✓ $1.9M
Jan 12, 2024 Jan 17, 2024 Hamilton James C Chief Discovery/Trans Medicine Sell 35.0 -7,940 -3.63% ✓ $292.9K
Jan 11, 2024 Jan 16, 2024 GIVEN DOUGLAS B Director Sell 41.3 -2,911 -2.19% ✓ $110.8K
Jan 11, 2024 Jan 16, 2024 Waddill William D. Director Sell 28.8 -3,934 -7.59% ✓ $149.8K
Jan 11, 2024 Jan 16, 2024 Ferrari Mauro Director Sell 37.5 -3,147 -4.92% ✓ $119.8K
Jan 11, 2024 Jan 16, 2024 Vakiener Victoria Director Sell 25.0 -4,720 -12.85% ✓ $179.8K
Jan 4, 2024 Jan 8, 2024 Oliver Tracie Chief Commercial Officer Sell 90.0 +74,926 121.68% ✓ $2.5K
Jan 4, 2024 Jan 8, 2024 Myszkowski Kenneth Allen CFO Sell 97.5 +58,896 15.43% ✓ $567.9K
Jan 4, 2024 Jan 8, 2024 San Martin Javier Chief Medical Officer Sell 97.5 +66,697 50.60% ✓ $292.8K
Jan 3, 2024 Jan 5, 2024 Hamilton James C Other Sell 100.0 +36,557 20.06% ✓ $1.3M
Jan 3, 2024 Jan 5, 2024 O'Brien Patrick COO Sell 100.0 +51,810 12.56% ✓ $1.1M
Jan 2, 2024 Jan 4, 2024 Anzalone Christopher Richard CEO Sell 46.3 -9,952 -0.27% ✓ $308.6K
Dec 20, 2023 Dec 22, 2023 Anzalone Christopher Richard CEO Sell 46.3 -12,000 -0.32% ✓ $342.5K
Dec 15, 2023 Dec 19, 2023 Ferrari Mauro Director Neutral 90.0 +14,987 29.48% ✗ -
Dec 15, 2023 Dec 19, 2023 PERRY MICHAEL S Director Neutral 90.0 +14,987 15.02% ✗ -
Dec 15, 2023 Dec 19, 2023 OLUKOTUN ADEOYE Y Director Neutral 90.0 +14,987 190.50% ✗ -
Dec 15, 2023 Dec 19, 2023 Vakiener Victoria Director Neutral 90.0 +14,987 68.96% ✗ -
Dec 15, 2023 Dec 19, 2023 GIVEN DOUGLAS B Director Neutral 90.0 +14,987 12.74% ✗ -
Dec 15, 2023 Dec 19, 2023 Waddill William D. Director Neutral 90.0 +14,987 40.71% ✗ -
Nov 20, 2023 Nov 22, 2023 San Martin Javier Chief Medical Officer Sell 20.0 -19,700 -13.00% ✗ $567.3K
Oct 25, 2023 Oct 27, 2023 Anzalone Christopher Richard CEO Sell 45.0 -24,338 -0.65% ✓ $589.2K
Sep 28, 2023 Oct 2, 2023 Vakiener Victoria Director Sell 26.3 -1,550 -6.66% ✗ $40.8K
Sep 18, 2023 Sep 20, 2023 Anzalone Christopher Richard CEO Sell 40.0 -57,755 -1.51% ✓ $1.6M
Jul 3, 2023 Jul 6, 2023 Oliver Tracie Chief Commercial Officer Sell 20.0 -8,925 -12.66% ✗ $315.1K
Jun 30, 2023 Jul 5, 2023 Hamilton James C Other Sell 22.5 -3,000 -1.57% ✗ $106.6K
Jun 27, 2023 Jun 29, 2023 Myszkowski Kenneth Allen CFO Sell 20.0 -15,000 -3.78% ✗ $543K
May 5, 2023 May 8, 2023 GIVEN DOUGLAS B Director Sell 20.0 -6,500 -4.34% ✗ $265.9K
May 3, 2023 May 5, 2023 Anzalone Christopher Richard CEO Sell 27.5 -104,928 -0.92% ✗ $4.1M
Mar 3, 2023 Mar 6, 2023 OLUKOTUN ADEOYE Y Director Sell 20.0 -11,350 -59.06% ✗ $370.6K
Feb 27, 2023 Mar 1, 2023 GIVEN DOUGLAS B Director Sell 36.3 -875 -0.63% ✗ $28.5K
Jan 10, 2023 Jan 12, 2023 Ferrari Mauro Director Neutral 90.0 +7,867 18.31% ✗ -
Jan 10, 2023 Jan 11, 2023 De Backer Marianne Director Neutral 90.0 +7,867 33.62% ✗ -
Jan 10, 2023 Jan 11, 2023 Vakiener Victoria Director Neutral 90.0 +6,103 35.52% ✗ -
Jan 10, 2023 Jan 11, 2023 PERRY MICHAEL S Director Neutral 85.0 +7,867 8.56% ✗ -
Jan 10, 2023 Jan 11, 2023 GIVEN DOUGLAS B Director Neutral 85.0 +7,867 6.77% ✗ -
Jan 9, 2023 Jan 11, 2023 Waddill William D. Director Sell 95.0 +4,667 14.52% ✓ $96K
Jan 10, 2023 Jan 11, 2023 OLUKOTUN ADEOYE Y Director Neutral 90.0 +7,867 69.31% ✗ -
Jan 5, 2023 Jan 6, 2023 O'Brien Patrick COO Sell 35.0 -15,000 -3.50% ✓ $560.9K
Jan 5, 2023 Jan 6, 2023 Hamilton James C Other Sell 30.0 -13,803 -6.72% ✓ $516.2K
Jan 4, 2023 Jan 5, 2023 Oliver Tracie Chief Commercial Officer Neutral 67.5 +500 0.71% ✗ -
Jan 4, 2023 Jan 5, 2023 San Martin Javier Chief Medical Officer Neutral 90.0 +60,000 65.57% ✗ -
Jan 4, 2023 Jan 5, 2023 Myszkowski Kenneth Allen CFO Neutral 90.0 +60,000 17.82% ✗ -