2026Q1
| Insider | Role (last 12 mo) | Shares held | Filed at |
|---|---|---|---|
| Redmile Group, LLC | — | 696,378 | Oct 29, 2019 |
| Green Jeremy | — | 696,378 | Oct 29, 2019 |
| Flynn James E | 10% Owner | 464,253 | Oct 30, 2019 |
| Deerfield Management Company, L.P. (Series C) | 10% Owner | 464,253 | Oct 30, 2019 |
| Deerfield Partners, L.P. | 10% Owner | 464,253 | Oct 30, 2019 |
| Exec date | Filing date | Insider | Role | Signal | Confidence | Shares | % of shares | Under plan? | Amount (USD) |
|---|---|---|---|---|---|---|---|---|---|
| Mar 2, 2026 | Mar 2, 2026 | Das Arun | Chief Business Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 2, 2026 | Mar 2, 2026 | Gerard Michael | General Counsel | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 2, 2026 | Mar 2, 2026 | Binder Gwendolyn | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 2, 2026 | Mar 2, 2026 | Chang David J. | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 2, 2026 | Mar 2, 2026 | Nichtberger Steven | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 2, 2026 | Mar 2, 2026 | Marda Anup | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 21, 2026 | Jan 21, 2026 | Chang David J. | Chief Medical Officer | Buy | 91.3 | +8,800 | 100.00% | ✗ | $19.9K |
| Jan 21, 2026 | Jan 21, 2026 | Binder Gwendolyn | President | Buy | 91.3 | +11,312 | 56.56% | ✗ | $24.8K |
| Jan 21, 2026 | Jan 21, 2026 | Tomasello Shawn | Director | Buy | 95.0 | +22,725 | 100.00% | ✗ | $50.3K |
| Jan 21, 2026 | Jan 21, 2026 | Gavel Steve | Chief Commercial Officer | Buy | 95.0 | +22,170 | 100.00% | ✗ | $50.2K |
| Jan 21, 2026 | Jan 21, 2026 | Bollard Catherine | Director | Buy | 90.0 | +4,405 | 440.50% | ✗ | $10K |
| Jan 21, 2026 | Jan 21, 2026 | Nichtberger Steven | CEO | Buy | 87.5 | +45,000 | 3.33% | ✗ | $100.8K |
| Jan 21, 2026 | Jan 21, 2026 | Simon Mark | Director | Buy | 86.3 | +11,061 | 7.73% | ✗ | $25.3K |
| Jan 21, 2026 | Jan 21, 2026 | Gerard Michael | General Counsel | Buy | 91.3 | +6,600 | 100.00% | ✗ | $15K |
| Oct 13, 2025 | Oct 15, 2025 | Gavel Steve | CHIEF COMMERCIAL OFFICER | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Oct 15, 2025 | Gavel Steve | CHIEF COMMERCIAL OFFICER | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jun 9, 2025 | Jun 9, 2025 | Simon Mark | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 9, 2025 | Jun 9, 2025 | Brun Scott C. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 9, 2025 | Jun 9, 2025 | Bollard Catherine | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 9, 2025 | Jun 9, 2025 | Tomasello Shawn | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 9, 2025 | Jun 9, 2025 | HENRIQUES RICHARD C JR | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 19, 2025 | May 19, 2025 | Brun Scott C. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 19, 2025 | May 19, 2025 | Nichtberger Steven | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 19, 2025 | May 19, 2025 | Gerard Michael | General Counsel | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 19, 2025 | May 19, 2025 | HENRIQUES RICHARD C JR | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 19, 2025 | May 19, 2025 | Tomasello Shawn | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 19, 2025 | May 19, 2025 | Marda Anup | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 19, 2025 | May 19, 2025 | Simon Mark | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 19, 2025 | May 19, 2025 | Binder Gwendolyn | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 19, 2025 | May 19, 2025 | Das Arun | Chief Business Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 19, 2025 | May 19, 2025 | Bollard Catherine | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 19, 2025 | May 19, 2025 | Chang David J. | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 3, 2025 | Mar 4, 2025 | Binder Gwendolyn | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 3, 2025 | Mar 4, 2025 | Marda Anup | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 3, 2025 | Mar 4, 2025 | Gerard Michael | General Counsel | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 3, 2025 | Mar 4, 2025 | Das Arun | Chief Business Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 3, 2025 | Mar 4, 2025 | Chang David J. | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 3, 2025 | Mar 4, 2025 | Nichtberger Steven | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 3, 2024 | Jun 4, 2024 | Bollard Catherine | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 3, 2024 | Jun 4, 2024 | Simon Mark | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 3, 2024 | Jun 4, 2024 | HENRIQUES RICHARD C JR | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 3, 2024 | Jun 4, 2024 | Brun Scott C. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 3, 2024 | Jun 4, 2024 | Tomasello Shawn | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 1, 2024 | Mar 4, 2024 | Gerard Michael | General Counsel | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 1, 2024 | Mar 4, 2024 | Chang David J. | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 1, 2024 | Mar 4, 2024 | Nichtberger Steven | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 1, 2024 | Mar 4, 2024 | Marda Anup | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 1, 2024 | Mar 4, 2024 | Das Arun | Chief Business Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 1, 2024 | Mar 4, 2024 | Binder Gwendolyn | Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 19, 2024 | Jan 19, 2024 | Binder Gwendolyn | Officer | Sell | 10.0 | -11,000 | -35.48% | ✓ | $215.4K |
| Dec 19, 2023 | Dec 19, 2023 | Binder Gwendolyn | Officer | Sell | 10.0 | -11,000 | -35.48% | ✓ | $240.8K |
| Nov 20, 2023 | Nov 21, 2023 | Binder Gwendolyn | Officer | Sell | 10.0 | -11,000 | -35.48% | ✓ | $196K |
| Oct 19, 2023 | Oct 19, 2023 | Binder Gwendolyn | Officer | Sell | 10.0 | -11,000 | -35.48% | ✓ | $146.9K |
| Sep 19, 2023 | Sep 20, 2023 | Binder Gwendolyn | Officer | Sell | 10.0 | -11,000 | -35.48% | ✓ | $193.2K |
| Aug 21, 2023 | Aug 22, 2023 | Binder Gwendolyn | Officer | Sell | 10.0 | -11,000 | -35.48% | ✓ | $147.6K |
| Jul 21, 2023 | Jul 24, 2023 | Tomasello Shawn | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 24, 2023 | Tomasello Shawn | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jul 19, 2023 | Jul 19, 2023 | Binder Gwendolyn | Officer | Sell | 10.0 | -11,000 | -35.48% | ✓ | $152K |
| Jun 20, 2023 | Jun 21, 2023 | Binder Gwendolyn | Officer | Sell | 10.0 | -11,000 | -35.48% | ✓ | $142.9K |
| Jun 1, 2023 | Jun 2, 2023 | Simon Mark | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 1, 2023 | Jun 2, 2023 | Bollard Catherine | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 1, 2023 | Jun 2, 2023 | HENRIQUES RICHARD C JR | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 1, 2023 | Jun 2, 2023 | Brun Scott C. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 19, 2023 | May 19, 2023 | Binder Gwendolyn | Officer | Sell | 7.5 | -22,000 | -52.38% | ✓ | $259.8K |
| Jan 18, 2023 | Jan 27, 2023 | Nichtberger Steven | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 18, 2023 | Jan 27, 2023 | Gerard Michael | General Counsel | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 18, 2023 | Jan 27, 2023 | Das Arun | Chief Business Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 18, 2023 | Jan 27, 2023 | Binder Gwendolyn | Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 18, 2023 | Jan 27, 2023 | Chang David J. | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 18, 2023 | Jan 27, 2023 | Marda Anup | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Oct 19, 2022 | Oct 19, 2022 | Nichtberger Steven | CEO | Buy | 68.8 | +8,127 | 0.61% | ✗ | $10.2K |
| Oct 18, 2022 | Oct 18, 2022 | Bollard Catherine | Director | Buy | 90.0 | +1,000 | 100.00% | ✗ | $993.5 |
| Oct 18, 2022 | Oct 18, 2022 | Marda Anup | CFO | Buy | 91.3 | +50,000 | 100.00% | ✗ | $49.6K |
| Oct 18, 2022 | Oct 18, 2022 | Simon Mark | Director | Buy | 95.0 | +125,000 | 688.93% | ✗ | $122.1K |
| Oct 18, 2022 | Oct 18, 2022 | Binder Gwendolyn | Officer | Buy | 91.3 | +20,000 | 100.00% | ✗ | $19.9K |
| Oct 18, 2022 | Oct 18, 2022 | Nichtberger Steven | CEO | Buy | 95.0 | +141,873 | 11.83% | ✗ | $141K |
| Jun 1, 2022 | Jun 3, 2022 | Brun Scott C. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 1, 2022 | Jun 3, 2022 | Simon Mark | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 1, 2022 | Jun 3, 2022 | Bollard Catherine | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 1, 2022 | Jun 3, 2022 | HENRIQUES RICHARD C JR | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 31, 2022 | Feb 2, 2022 | Nichtberger Steven | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 18, 2022 | Jan 19, 2022 | Marda Anup | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 18, 2022 | Jan 19, 2022 | Gerard Michael | General Counsel | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 18, 2022 | Jan 19, 2022 | Das Arun | Chief Business Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 18, 2022 | Jan 19, 2022 | Chang David J. | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 18, 2022 | Jan 19, 2022 | Nichtberger Steven | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 18, 2022 | Jan 19, 2022 | Binder Gwendolyn | Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 13, 2022 | Das Arun | Chief Business Officer | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Nov 1, 2021 | Nov 3, 2021 | 5AM Ventures V, L.P. | 10% Owner | Sell | 17.5 | -295,000 | -12.50% | ✗ | $3.8M |
| Sep 7, 2021 | Sep 9, 2021 | 5AM Ventures V, L.P. | 10% Owner | Sell | 16.3 | -625,000 | -23.90% | ✗ | $6.1M |
| Sep 1, 2021 | Sep 3, 2021 | Gerard Michael | General Counsel | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 3, 2021 | Gerard Michael | General Counsel | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jun 24, 2021 | Jun 28, 2021 | Brun Scott C. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 1, 2021 | Jun 28, 2021 | DANIELS BRIAN | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 28, 2021 | Brun Scott C. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jun 1, 2021 | Jun 3, 2021 | Simon Mark | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 1, 2021 | Jun 3, 2021 | HENRIQUES RICHARD C JR | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 1, 2021 | Jun 3, 2021 | Bollard Catherine | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 1, 2021 | Jun 3, 2021 | DANIELS BRIAN | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 1, 2021 | Mar 2, 2021 | Stalter John Brian | General Counsel | Neutral | 52.5 | - | 0.00% | ✗ | - |