2026Q1
| Insider | Role (last 12 mo) | Shares held | Filed at |
|---|---|---|---|
| Opko Health, Inc. | — | 18,696,301 | Mar 17, 2014 |
| Schinazi Raymond F | 10% Owner | 7,674,960 | May 6, 2021 |
| Rubin Steven D | Director | 2,660,242 | Oct 11, 2024 |
| Mayers Douglas L | — | 2,400,000 | Oct 2, 2015 |
| Frost Gamma Investments Trust | 10% Owner | 1,319,838 | Apr 6, 2023 |
| Exec date | Filing date | Insider | Role | Signal | Confidence | Shares | % of shares | Under plan? | Amount (USD) |
|---|---|---|---|---|---|---|---|---|---|
| Feb 24, 2026 | Feb 25, 2026 | FROST PHILLIP MD ET AL | Director | Buy | 78.8 | +20,000 | 1.04% | ✗ | $20K |
| Feb 6, 2026 | Feb 9, 2026 | FROST PHILLIP MD ET AL | Director | Buy | 83.8 | +50,000 | 2.68% | ✗ | $47.3K |
| Jan 9, 2026 | Jan 13, 2026 | Kornberg Roger D. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 9, 2026 | Jan 13, 2026 | PFENNIGER RICHARD C JR | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 9, 2026 | Jan 13, 2026 | Lee Sam | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 9, 2026 | Jan 13, 2026 | Hassan Fred | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 9, 2026 | Jan 13, 2026 | Martin James Joseph | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 9, 2026 | Jan 13, 2026 | FROST PHILLIP MD ET AL | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 9, 2026 | Jan 13, 2026 | Japour Anthony J | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 9, 2026 | Jan 13, 2026 | Rubin Steven D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 31, 2025 | Jan 2, 2026 | FROST PHILLIP MD ET AL | Director | Buy | 83.8 | +50,000 | 2.75% | ✗ | $47.3K |
| Dec 30, 2025 | Dec 31, 2025 | FROST PHILLIP MD ET AL | Director | Buy | 78.8 | +20,000 | 1.11% | ✗ | $19.3K |
| Dec 24, 2025 | Dec 29, 2025 | FROST PHILLIP MD ET AL | Director | Buy | 87.5 | +65,000 | 3.76% | ✗ | $63.2K |
| Nov 26, 2025 | Nov 28, 2025 | FROST PHILLIP MD ET AL | Director | Buy | 60.0 | +4,000 | 0.23% | ✗ | $4K |
| Nov 25, 2025 | Nov 25, 2025 | FROST PHILLIP MD ET AL | Director | Buy | 78.8 | +20,000 | 1.17% | ✗ | $18.8K |
| Oct 28, 2025 | Oct 30, 2025 | FROST PHILLIP MD ET AL | Director | Neutral | 90.0 | +359,713 | 26.71% | ✗ | - |
| Oct 28, 2025 | Oct 30, 2025 | Hassan Fred | Director | Neutral | 90.0 | +359,713 | 35.15% | ✗ | - |
| Oct 28, 2025 | Oct 30, 2025 | PFENNIGER RICHARD C JR | Director | Neutral | 90.0 | +20,000 | 175.44% | ✗ | - |
| Oct 28, 2025 | Oct 30, 2025 | Martin James Joseph | CEO | Neutral | 85.0 | +3,598 | 8.87% | ✗ | - |
| Oct 9, 2024 | Oct 11, 2024 | Kornberg Roger D. | Director | Neutral | 90.0 | +28,109 | 70.68% | ✗ | - |
| Oct 9, 2024 | Oct 11, 2024 | FROST PHILLIP MD ET AL | Director | Neutral | 77.5 | +27,100 | 2.05% | ✗ | - |
| Oct 9, 2024 | Oct 11, 2024 | Rubin Steven D | Director | Neutral | 67.5 | +18,957 | 0.72% | ✗ | - |
| Oct 9, 2024 | Oct 11, 2024 | Lee Sam | CEO | Neutral | 90.0 | +40,000 | 110.03% | ✗ | - |
| Oct 9, 2024 | Oct 11, 2024 | PFENNIGER RICHARD C JR | Director | Neutral | 90.0 | +8,067 | 242.03% | ✗ | - |
| Oct 9, 2024 | Oct 11, 2024 | Martin James Joseph | CEO | Neutral | 90.0 | +40,000 | 7029.88% | ✗ | - |
| Oct 9, 2024 | Oct 11, 2024 | Japour Anthony J | Director | Neutral | 90.0 | +14,924 | 100.00% | ✗ | - |
| Oct 9, 2024 | Oct 11, 2024 | Hassan Fred | Director | Neutral | 67.5 | +8,067 | 0.79% | ✗ | - |
| Jul 18, 2023 | Jul 20, 2023 | FROST PHILLIP MD ET AL | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 18, 2023 | Jul 20, 2023 | Japour Anthony J | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 18, 2023 | Jul 20, 2023 | Martin James Joseph | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 18, 2023 | Jul 20, 2023 | Kornberg Roger D. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 18, 2023 | Jul 20, 2023 | Lee Sam | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 18, 2023 | Jul 20, 2023 | PFENNIGER RICHARD C JR | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 18, 2023 | Jul 20, 2023 | Hassan Fred | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 18, 2023 | Jul 20, 2023 | Rubin Steven D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 27, 2023 | Hassan Fred | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Apr 4, 2023 | Apr 6, 2023 | FROST PHILLIP MD ET AL | Director | Buy | 100.0 | +1,015,229 | 333.29% | ✗ | $2M |
| Jul 25, 2022 | Aug 3, 2022 | Japour Anthony J | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 25, 2022 | Aug 3, 2022 | Martin James Joseph | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 25, 2022 | Aug 3, 2022 | PFENNIGER RICHARD C JR | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 25, 2022 | Aug 3, 2022 | FROST PHILLIP MD ET AL | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 25, 2022 | Aug 3, 2022 | Rubin Steven D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 25, 2022 | Aug 3, 2022 | Kornberg Roger D. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 25, 2022 | Aug 3, 2022 | Lee Sam | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Aug 20, 2021 | Aug 23, 2021 | PFENNIGER RICHARD C JR | Director | Buy | 91.3 | +40,000 | 100.00% | ✗ | $41.1K |
| Jul 16, 2021 | Jul 20, 2021 | PFENNIGER RICHARD C JR | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 16, 2021 | Jul 20, 2021 | Kornberg Roger D. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 16, 2021 | Jul 20, 2021 | Martin James Joseph | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 16, 2021 | Jul 20, 2021 | Rubin Steven D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 16, 2021 | Jul 20, 2021 | Japour Anthony J | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 16, 2021 | Jul 20, 2021 | Lee Sam | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 16, 2021 | Jul 20, 2021 | FROST PHILLIP MD ET AL | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 2, 2021 | PFENNIGER RICHARD C JR | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| May 4, 2021 | May 6, 2021 | Schinazi Raymond F | 10% Owner | Sell | 17.5 | -575,000 | -6.97% | ✗ | $1.7M |
| Nov 24, 2020 | Feb 12, 2021 | Lee Sam | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 22, 2020 | Jun 24, 2020 | Lee Sam | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 22, 2020 | Jun 24, 2020 | Japour Anthony J | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 22, 2020 | Jun 24, 2020 | WILCOX GARY | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 22, 2020 | Jun 24, 2020 | Kornberg Roger D. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 22, 2020 | Jun 24, 2020 | Martin James Joseph | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 22, 2020 | Jun 24, 2020 | FROST PHILLIP MD ET AL | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 22, 2020 | Jun 24, 2020 | Rubin Steven D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 27, 2020 | Kornberg Roger D. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Oct 23, 2019 | Oct 29, 2019 | Schinazi Raymond F | 10% Owner | Buy | 56.3 | +16,935 | 0.17% | ✗ | $19K |
| Apr 15, 2019 | Japour Anthony J | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Feb 11, 2019 | Brady Todd R. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Sep 21, 2018 | Sep 24, 2018 | HSIAO JANE PH D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 21, 2018 | Sep 24, 2018 | Lee Sam | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 21, 2018 | Sep 24, 2018 | Rubin Steven D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 21, 2018 | Sep 24, 2018 | FROST PHILLIP MD ET AL | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 21, 2018 | Sep 24, 2018 | Schinazi Raymond F | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 21, 2018 | Sep 24, 2018 | BLOCK DAVID S | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 21, 2018 | Sep 24, 2018 | WILCOX GARY | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 21, 2018 | Sep 24, 2018 | Martin James Joseph | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 10, 2018 | May 14, 2018 | Schinazi Raymond F | Director | Neutral | 55.0 | +10,209 | 0.10% | ✗ | - |
| May 3, 2018 | May 7, 2018 | Schinazi Raymond F | Director | Neutral | 82.5 | +420,737 | 4.02% | ✗ | - |
| May 3, 2018 | May 7, 2018 | FROST PHILLIP MD ET AL | Director | Neutral | 82.5 | +105,263 | 2.97% | ✗ | - |
| Nov 24, 2017 | Dec 8, 2017 | Schinazi Raymond F | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 11, 2017 | Jul 13, 2017 | Schinazi Raymond F | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 20, 2017 | Apr 24, 2017 | Schinazi Raymond F | Director | Neutral | 77.5 | +4,166,667 | 1.49% | ✗ | - |
| Mar 6, 2017 | Martin James Joseph | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Dec 23, 2016 | Dec 23, 2016 | Lee Sam | President | Sell | 20.0 | -2,200,000 | -14.39% | ✗ | $968K |
| Sep 1, 2016 | Sep 6, 2016 | BLOCK DAVID S | Director | Buy | 85.0 | +10,000 | 6.30% | ✗ | $4.1K |
| Sep 1, 2016 | Sep 6, 2016 | Schinazi Raymond F | Director | Buy | 87.5 | +4,878,050 | 1.77% | ✗ | $2M |
| Sep 1, 2016 | Sep 6, 2016 | WILCOX GARY | CEO | Buy | 55.0 | +10,000 | 0.06% | ✗ | $4.1K |
| Mar 15, 2016 | Mar 18, 2016 | Rubin Steven D | Director | Buy | 86.3 | +39,216 | 5.65% | ✗ | $20K |
| Mar 15, 2016 | Mar 17, 2016 | FROST PHILLIP MD ET AL | Director | Buy | 92.5 | +2,941,177 | 2.84% | ✗ | $1.5M |
| Mar 15, 2016 | Mar 17, 2016 | Meckler Jeffrey A | CEO | Buy | 95.0 | +294,118 | 81.01% | ✗ | $150K |
| Mar 15, 2016 | Mar 17, 2016 | BLOCK DAVID S | Director | Buy | 91.3 | +50,000 | 46.00% | ✗ | $25.5K |
| Mar 15, 2016 | Mar 17, 2016 | WILCOX GARY | Director | Buy | 61.3 | +49,020 | 0.29% | ✗ | $25K |
| Mar 15, 2016 | Mar 17, 2016 | Rubin Steven D | Director | Buy | 91.3 | +39,216 | 72.16% | ✗ | $20K |
| Mar 15, 2016 | Mar 17, 2016 | Schinazi Raymond F | Director | Buy | 87.5 | +2,941,176 | 1.08% | ✗ | $1.5M |
| Mar 15, 2016 | Mar 17, 2016 | HSIAO JANE PH D | Director | Buy | 97.5 | +1,235,294 | 16.05% | ✗ | $630K |
| Dec 23, 2015 | Dec 28, 2015 | Meckler Jeffrey A | CEO | Buy | 95.0 | +100,000 | 38.02% | ✗ | $57.9K |
| Nov 24, 2015 | Nov 25, 2015 | Dale Curtis | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 25, 2015 | Dale Curtis | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Oct 1, 2015 | Oct 2, 2015 | Meckler Jeffrey A | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Oct 1, 2015 | Oct 2, 2015 | Mayers Douglas L | CHIEF MEDICAL OFFICER | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Oct 2, 2015 | Mayers Douglas L | CHIEF MEDICAL OFFICER | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jul 21, 2015 | Jul 23, 2015 | Linscott Walt Addison | GENERAL COUNSEL AND SECRETARY | Neutral | 52.5 | - | 0.00% | ✗ | - |