Design Therapeutics, Inc. (DSGN)

Latest Insider Confidence Score

2026Q1

49.8
Bearish

Company insider confidence (by quarter)

2021Q1 2026Q1

Largest shareholders

Insider Role (last 12 mo) Shares held Filed at
Sr One Capital Management, Llc 10% Owner 6,526,476 Dec 20, 2022
Sr One Capital Partners I, Lp 10% Owner 6,526,476 Dec 20, 2022
SR One Capital Fund I Aggregator LP 10% Owner 6,526,476 Dec 20, 2022
Star Irrevocable Trust #1 dated April 22, 2019 — 3,834,355 Mar 25, 2021
Light Irrevocable Trust #1 dated April 22, 2019 — 3,834,355 Mar 25, 2021

Recent buy/sell transactions

Exec date Filing date Insider Role Signal Confidence Shares % of shares Under plan? Amount (USD)
Jan 2, 2026 Jan 5, 2026 Storgard Chris Chief Medical Officer Neutral 52.5 - 0.00% ✗ -
Jan 2, 2026 Jan 5, 2026 Jeffries Sean COO Neutral 52.5 - 0.00% ✗ -
Jan 2, 2026 Jan 5, 2026 Burgess Julie Chief Accounting Officer Neutral 52.5 - 0.00% ✗ -
Jan 2, 2026 Jan 5, 2026 Gover Justin D. Director Neutral 52.5 - 0.00% ✗ -
Jan 2, 2026 Jan 5, 2026 Shah Pratik CEO Neutral 52.5 - 0.00% ✗ -
Dec 9, 2025 Dec 11, 2025 Shah Pratik CEO Neutral 52.5 - 0.00% ✗ -
Sep 9, 2025 Sep 10, 2025 Gover Justin D. Director Neutral 52.5 - 0.00% ✗ -
Sep 10, 2025 Gover Justin D. Director Neutral 52.5 - 0.00% ✗ -
Aug 13, 2025 Aug 14, 2025 William Arsani Director Sell 17.5 -562,627 -13.34% ✗ $3M
Jun 10, 2025 Jun 12, 2025 George Simeon Director Neutral 52.5 - 0.00% ✗ -
Jun 10, 2025 Jun 12, 2025 Prasad Deepa Director Neutral 52.5 - 0.00% ✗ -
Jun 10, 2025 Jun 12, 2025 William Arsani Director Neutral 52.5 - 0.00% ✗ -
Jun 10, 2025 Jun 12, 2025 Berger Heather A. Director Neutral 52.5 - 0.00% ✗ -
Jun 10, 2025 Jun 12, 2025 Schmid John P. Director Neutral 52.5 - 0.00% ✗ -
Jun 10, 2025 Jun 12, 2025 LAPPE RODNEY W Director Neutral 52.5 - 0.00% ✗ -
May 1, 2025 May 23, 2025 Storgard Chris Chief Medical Officer Neutral 52.5 - 0.00% ✗ -
May 23, 2025 Storgard Chris Chief Medical Officer Neutral 52.5 - 0.00% ✗ -
Feb 7, 2025 DUNHAM TRUST Co 10% Owner Neutral 52.5 - 0.00% ✗ -
Jan 2, 2025 Jan 6, 2025 LAPPE RODNEY W Director Neutral 52.5 - 0.00% ✗ -
Jan 2, 2025 Jan 6, 2025 Burgess Julie Chief Accounting Officer Neutral 52.5 - 0.00% ✗ -
Jan 2, 2025 Jan 6, 2025 Shah Pratik CEO Neutral 52.5 - 0.00% ✗ -
Jan 2, 2025 Jan 6, 2025 Jeffries Sean COO Neutral 52.5 - 0.00% ✗ -
Dec 18, 2024 Dec 19, 2024 Prasad Deepa Director Sell 26.3 -3,806 -15.99% ✗ $23.9K
Aug 9, 2024 Aug 12, 2024 William Arsani Director Sell 17.5 -814,874 -16.19% ✗ $3.5M
Jun 13, 2024 Jun 17, 2024 George Simeon Director Neutral 52.5 - 0.00% ✗ -
Jun 13, 2024 Jun 17, 2024 William Arsani Director Neutral 52.5 - 0.00% ✗ -
Jun 13, 2024 Jun 17, 2024 LAPPE RODNEY W Director Neutral 52.5 - 0.00% ✗ -
Jun 13, 2024 Jun 17, 2024 Schmid John P. Director Neutral 52.5 - 0.00% ✗ -
Jun 13, 2024 Jun 17, 2024 Berger Heather A. Director Neutral 52.5 - 0.00% ✗ -
Jun 13, 2024 Jun 17, 2024 Prasad Deepa Director Neutral 52.5 - 0.00% ✗ -
Mar 22, 2024 Mar 25, 2024 Schmid John P. Director Buy 95.0 +26,965 87.91% ✗ $99.7K
Mar 25, 2024 Mar 25, 2024 Berger Heather A. Director Buy 90.0 +1,300 100.00% ✗ $4.9K
Mar 20, 2024 Kim Jae B. Chief Medical Officer Neutral 52.5 - 0.00% ✗ -
Jan 2, 2024 Jan 5, 2024 Burgess Julie Chief Accounting Officer Neutral 52.5 - 0.00% ✗ -
Jan 2, 2024 Jan 5, 2024 Jeffries Sean COO Neutral 52.5 - 0.00% ✗ -
Dec 1, 2023 Dec 5, 2023 LAPPE RODNEY W Director Neutral 52.5 - 0.00% ✗ -
Dec 1, 2023 Dec 5, 2023 Ansari Aseem Z. 10% Owner Neutral 52.5 - 0.00% ✗ -
Sep 29, 2023 Oct 2, 2023 LAPPE RODNEY W Director Buy 91.3 +21,000 18.75% ✗ $49.3K
Mar 30, 2021 Sep 6, 2023 William Arsani Director Buy 100.0 +700,000 100.00% ✗ $14M
Sep 1, 2023 Sep 5, 2023 Shah Pratik CEO Neutral 52.5 - 0.00% ✗ -
Aug 29, 2023 Aug 30, 2023 Prasad Deepa Director Buy 91.3 +12,000 101.64% ✗ $27.7K
Aug 28, 2023 Aug 30, 2023 William Arsani Director Buy 100.0 +2,235,000 79.89% ✗ $5.4M
May 31, 2023 Jun 2, 2023 George Simeon Director Neutral 52.5 - 0.00% ✗ -
May 31, 2023 Jun 2, 2023 Prasad Deepa Director Neutral 52.5 - 0.00% ✗ -
May 31, 2023 Jun 2, 2023 Schmid John P. Director Neutral 52.5 - 0.00% ✗ -
May 31, 2023 Jun 2, 2023 Xu Stella Director Neutral 52.5 - 0.00% ✗ -
May 31, 2023 Jun 2, 2023 William Arsani Director Neutral 52.5 - 0.00% ✗ -
May 31, 2023 Jun 2, 2023 Berger Heather A. Director Neutral 52.5 - 0.00% ✗ -
May 31, 2023 Jun 2, 2023 LAPPE RODNEY W Director Neutral 52.5 - 0.00% ✗ -
Feb 1, 2023 Feb 3, 2023 Burgess Julie Chief Accounting Officer Neutral 52.5 - 0.00% ✗ -
Feb 1, 2023 Feb 3, 2023 Jeffries Sean COO Neutral 52.5 - 0.00% ✗ -
Feb 1, 2023 Feb 3, 2023 Shah Pratik Chair Neutral 52.5 - 0.00% ✗ -
Feb 1, 2023 Feb 3, 2023 Siffert Joao MD CEO Neutral 52.5 - 0.00% ✗ -
Dec 19, 2022 Dec 21, 2022 Siffert Joao MD CEO Buy 90.0 +7,450 5.95% ✗ $62.5K
Dec 16, 2022 Dec 20, 2022 George Simeon Director Buy 100.0 +900,000 16.00% ✗ $7.6M
Dec 16, 2022 Dec 20, 2022 SR One Capital Fund I Aggregator LP 10% Owner Buy 100.0 +900,000 16.00% ✗ $7.6M
Dec 9, 2022 Dec 12, 2022 LAPPE RODNEY W Director Buy 95.0 +15,000 15.46% ✗ $119.4K
Jun 15, 2022 Jun 16, 2022 Xu Stella Director Neutral 52.5 - 0.00% ✗ -
Jun 15, 2022 Jun 16, 2022 LAPPE RODNEY W Director Neutral 52.5 - 0.00% ✗ -
Jun 15, 2022 Jun 16, 2022 Schmid John P. Director Neutral 52.5 - 0.00% ✗ -
Jun 15, 2022 Jun 16, 2022 William Arsani Director Neutral 52.5 - 0.00% ✗ -
Jun 15, 2022 Jun 16, 2022 George Simeon Director Neutral 52.5 - 0.00% ✗ -
Jun 15, 2022 Jun 16, 2022 Prasad Deepa Director Neutral 52.5 - 0.00% ✗ -
Jun 15, 2022 Jun 16, 2022 Berger Heather A. Director Neutral 52.5 - 0.00% ✗ -
Mar 21, 2022 Mar 22, 2022 William Arsani Director Buy 67.5 +25,000 0.42% ✗ $474.7K
Mar 18, 2022 Mar 22, 2022 Xu Stella Director Sell 15.0 -590,880 -12.49% ✗ $11.3M
Mar 16, 2022 Mar 18, 2022 Prasad Deepa Director Neutral 90.0 +11,806 100.00% ✗ -
Feb 1, 2022 Feb 2, 2022 Jeffries Sean COO Neutral 52.5 - 0.00% ✗ -
Feb 1, 2022 Feb 2, 2022 Shah Pratik Chair Neutral 52.5 - 0.00% ✗ -
Feb 1, 2022 Feb 2, 2022 Siffert Joao MD CEO Neutral 52.5 - 0.00% ✗ -
Feb 1, 2022 Feb 2, 2022 Burgess Julie Chief Accounting Officer Neutral 52.5 - 0.00% ✗ -
Oct 1, 2021 Oct 4, 2021 Burgess Julie Chief Accounting Officer Neutral 52.5 - 0.00% ✗ -
Sep 20, 2021 Burgess Julie Chief Accounting Officer Neutral 52.5 - 0.00% ✗ -
Aug 31, 2021 Sep 2, 2021 William Arsani Director Buy 75.0 +40,000 0.67% ✗ $618K
Aug 17, 2021 Giangiulio Dawn Principal Accounting Officer Neutral 52.5 - 0.00% ✗ -
Jun 15, 2021 Jun 16, 2021 Prasad Deepa Director Neutral 52.5 - 0.00% ✗ -
Jun 16, 2021 Prasad Deepa Director Neutral 52.5 - 0.00% ✗ -
Jun 15, 2021 Jun 16, 2021 Behanna Heather Director Neutral 52.5 - 0.00% ✗ -
Jun 16, 2021 Behanna Heather Director Neutral 52.5 - 0.00% ✗ -
Mar 30, 2021 Apr 1, 2021 Jeffries Sean COO Buy 95.0 +3,050 100.00% ✗ $61K
Mar 30, 2021 Apr 1, 2021 Quan Venture Fund II, L.P. 10% Owner Neutral 52.5 - 0.00% ✗ -
Mar 30, 2021 Apr 1, 2021 SR One Capital Fund I Aggregator LP 10% Owner Buy 93.8 +250,000 4.65% ✗ $5M
Mar 30, 2021 Apr 1, 2021 Xu Stella Director Buy 65.0 +10,000 0.21% ✗ $200K
Mar 30, 2021 Apr 1, 2021 George Simeon Director Buy 93.8 +250,000 4.65% ✗ $5M
Mar 30, 2021 Apr 1, 2021 LAPPE RODNEY W Director Buy 90.0 +5,000 5.43% ✗ $100K
Mar 30, 2021 Apr 1, 2021 Shah Pratik Chair Buy 97.5 +25,000 100.00% ✗ $500K
Mar 30, 2021 Apr 1, 2021 Thacker Justin President Buy 97.5 +17,500 100.00% ✗ $350K
Mar 30, 2021 Apr 1, 2021 William Arsani Director Buy 100.0 +700,000 34.44% ✗ $14M
Mar 30, 2021 Apr 1, 2021 Cormorant Asset Management, LP Other Buy 100.0 +750,000 17.18% ✗ $15M
Mar 30, 2021 SR One Capital Fund I Aggregator LP 10% Owner Neutral 52.5 - 0.00% ✗ -
Mar 25, 2021 Mar 29, 2021 Xu Stella Director Neutral 52.5 - 0.00% ✗ -
Mar 25, 2021 Mar 29, 2021 William Arsani Director Neutral 52.5 - 0.00% ✗ -
Mar 25, 2021 Mar 29, 2021 Schmid John P. Director Neutral 52.5 - 0.00% ✗ -
Mar 25, 2021 Mar 29, 2021 LAPPE RODNEY W Director Neutral 52.5 - 0.00% ✗ -
Mar 25, 2021 Mar 29, 2021 George Simeon Director Neutral 52.5 - 0.00% ✗ -
Mar 25, 2021 SR One Capital Fund I Aggregator LP 10% Owner Neutral 52.5 - 0.00% ✗ -
Mar 25, 2021 Xu Stella Director Neutral 52.5 - 0.00% ✗ -
Mar 25, 2021 William Arsani Director Neutral 52.5 - 0.00% ✗ -
Mar 25, 2021 Thacker Justin President Neutral 52.5 - 0.00% ✗ -
Mar 25, 2021 Star Irrevocable Trust #1 dated April 22, 2019 10% Owner Neutral 52.5 - 0.00% ✗ -