2026Q1
| Insider | Role (last 12 mo) | Shares held | Filed at |
|---|---|---|---|
| Sands Frank M. | 10% Owner | 13,018,965 | Nov 24, 2025 |
| Sands Capital Life Sciences Pulse Fund II, L.P. | 10% Owner | 13,018,965 | Nov 24, 2025 |
| Sands Capital Ventures, LLC | 10% Owner | 13,018,965 | Nov 24, 2025 |
| Kalman Daniel | — | 1,748,312 | Dec 22, 2020 |
| Cabell Christopher | — | 1,014,846 | Aug 28, 2025 |
| Exec date | Filing date | Insider | Role | Signal | Confidence | Shares | % of shares | Under plan? | Amount (USD) |
|---|---|---|---|---|---|---|---|---|---|
| Feb 21, 2026 | Feb 24, 2026 | Aurentz Vincent | Director | Neutral | 27.5 | -255,299 | -33.33% | ✗ | - |
| Feb 21, 2026 | Feb 24, 2026 | Cabell Christopher | President | Neutral | 27.5 | -338,282 | -33.33% | ✗ | - |
| Feb 21, 2026 | Feb 24, 2026 | Munshi Amit | Director | Neutral | 27.5 | -19,089 | -4.52% | ✗ | - |
| Jan 5, 2026 | Jan 7, 2026 | Iwicki Mark T | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 5, 2026 | Jan 7, 2026 | Cabell Christopher | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 5, 2026 | Jan 7, 2026 | McIntyre David | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 21, 2025 | Nov 24, 2025 | Sands Capital Life Sciences Pulse Fund II, L.P. | 10% Owner | Buy | 100.0 | +2,068,965 | 18.89% | ✗ | $3M |
| Aug 28, 2025 | Cabell Christopher | President | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Aug 28, 2025 | Aurentz Vincent | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Feb 21, 2025 | Aug 28, 2025 | Munshi Amit | Director | Neutral | 90.0 | +57,265 | 15.69% | ✗ | - |
| Jul 15, 2025 | Sands Capital Life Sciences Pulse Fund II, L.P. | 10% Owner | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Feb 21, 2025 | Jul 2, 2025 | Cabell Christopher | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 21, 2025 | Jul 2, 2025 | Iwicki Mark T | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 21, 2025 | Jul 2, 2025 | Aurentz Vincent | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 30, 2025 | Jul 2, 2025 | Aurentz Vincent | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 30, 2025 | Jul 2, 2025 | Canner David | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 30, 2025 | Jul 2, 2025 | Munshi Amit | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 30, 2025 | Jul 2, 2025 | Kush Arvind | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 30, 2025 | Jul 2, 2025 | BERMAN DENNIS N | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 30, 2025 | Jul 2, 2025 | Bellini Roberto | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 14, 2025 | Apr 16, 2025 | McIntyre David | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 16, 2025 | McIntyre David | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Feb 21, 2025 | Feb 25, 2025 | Cabell Christopher | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 21, 2025 | Feb 25, 2025 | Aurentz Vincent | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 21, 2025 | Feb 25, 2025 | Iwicki Mark T | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 25, 2025 | Cabell Christopher | President | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Feb 25, 2025 | Aurentz Vincent | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Feb 14, 2025 | Feb 19, 2025 | Iwicki Mark T | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 19, 2025 | Iwicki Mark T | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Feb 14, 2025 | Feb 19, 2025 | Kush Arvind | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 14, 2025 | Feb 19, 2025 | Bellini Roberto | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 14, 2025 | Feb 19, 2025 | Freeman Roy Lester | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 14, 2025 | Feb 19, 2025 | Munshi Amit | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 14, 2025 | Feb 19, 2025 | Canner David | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 21, 2025 | Feb 19, 2025 | BERMAN DENNIS N | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 14, 2025 | Feb 19, 2025 | BERMAN DENNIS N | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 21, 2025 | Jan 22, 2025 | Lees-Rolfe Garth | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 21, 2025 | Jan 22, 2025 | Freeman Roy Lester | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 21, 2025 | Jan 22, 2025 | Werner Milton H. | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 21, 2025 | Jan 22, 2025 | BERMAN DENNIS N | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 3, 2025 | Jan 7, 2025 | Werner Milton H. | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 3, 2025 | Jan 7, 2025 | Lees-Rolfe Garth | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 3, 2025 | Jan 7, 2025 | Freeman Roy Lester | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 3, 2025 | Jan 7, 2025 | BERMAN DENNIS N | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Oct 25, 2024 | Sands Capital Life Sciences Pulse Fund II, L.P. | 10% Owner | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Oct 21, 2024 | Oct 23, 2024 | Canner David | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Oct 21, 2024 | Oct 23, 2024 | Bellini Roberto | Director | Buy | 100.0 | +1,460,000 | 100.00% | ✗ | $2M |
| Oct 21, 2024 | Oct 23, 2024 | Kush Arvind | Director | Buy | 95.0 | +145,000 | 100.00% | ✗ | $198.7K |
| Oct 21, 2024 | Oct 23, 2024 | Munshi Amit | Director | Buy | 97.5 | +365,000 | 100.00% | ✗ | $500.1K |
| Oct 23, 2024 | Kush Arvind | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Oct 23, 2024 | Canner David | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Oct 23, 2024 | Munshi Amit | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Oct 23, 2024 | Bellini Roberto | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jul 16, 2024 | Jul 18, 2024 | GRINT PAUL C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 16, 2024 | Jul 18, 2024 | Dion Gisele | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 16, 2024 | Jul 18, 2024 | BERMAN DENNIS N | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 16, 2024 | Jul 18, 2024 | Freeman Roy Lester | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 1, 2024 | Apr 3, 2024 | Werner Milton H. | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 1, 2024 | Apr 2, 2024 | Lees-Rolfe Garth | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 2, 2024 | Lees-Rolfe Garth | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jun 30, 2023 | Jul 5, 2023 | BERMAN DENNIS N | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 30, 2023 | Jul 5, 2023 | Dion Gisele | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 30, 2023 | Jul 5, 2023 | GRINT PAUL C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 30, 2023 | Jul 5, 2023 | Freeman Roy Lester | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 1, 2023 | Mar 3, 2023 | Werner Milton H. | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 1, 2023 | Mar 3, 2023 | FRATTAROLI JOSEPH | Cheif Financial Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 1, 2022 | Sep 6, 2022 | Dion Gisele | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 6, 2022 | Dion Gisele | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Aug 16, 2022 | Aug 16, 2022 | Werner Milton H. | CEO | Buy | 55.0 | +5,000 | 0.09% | ✗ | $4K |
| Jun 24, 2022 | Jun 28, 2022 | Freeman Roy Lester | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 24, 2022 | Jun 28, 2022 | GRINT PAUL C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 24, 2022 | Jun 28, 2022 | O'Farrell Elizabeth G. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 24, 2022 | Jun 28, 2022 | BERMAN DENNIS N | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 27, 2022 | May 31, 2022 | Werner Milton H. | CEO | Buy | 55.0 | +5,000 | 0.09% | ✗ | $4.9K |
| May 20, 2022 | May 23, 2022 | Werner Milton H. | CEO | Buy | 55.0 | +10,000 | 0.19% | ✗ | $6K |
| May 19, 2022 | May 23, 2022 | FRATTAROLI JOSEPH | CFO | Buy | 85.0 | +3,948 | 8.94% | ✗ | $2.5K |
| Mar 7, 2022 | Mar 21, 2022 | FRATTAROLI JOSEPH | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 7, 2022 | Mar 21, 2022 | Werner Milton H. | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 7, 2022 | Mar 9, 2022 | FRATTAROLI JOSEPH | Cheif Financial Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 7, 2022 | Mar 9, 2022 | Werner Milton H. | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 3, 2022 | Jan 4, 2022 | Werner Milton H. | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 17, 2021 | Nov 19, 2021 | Werner Milton H. | CEO | Buy | 61.3 | +23,589 | 0.44% | ✗ | $46.6K |
| Aug 17, 2021 | Aug 19, 2021 | Werner Milton H. | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 25, 2021 | Jun 29, 2021 | O'Farrell Elizabeth G. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 25, 2021 | Jun 29, 2021 | GRINT PAUL C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 25, 2021 | Jun 29, 2021 | Freeman Roy Lester | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 25, 2021 | Jun 29, 2021 | BERMAN DENNIS N | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 14, 2021 | May 18, 2021 | Werner Milton H. | CEO | Sell | 40.0 | -16,918 | -0.32% | ✗ | $77.7K |
| Dec 22, 2020 | Dec 29, 2020 | BERMAN DENNIS N | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 22, 2020 | Dec 29, 2020 | O'Farrell Elizabeth G. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 22, 2020 | Dec 29, 2020 | GRINT PAUL C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 22, 2020 | Dec 29, 2020 | Freeman Roy Lester | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 22, 2020 | Dec 29, 2020 | Werner Milton H. | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 28, 2020 | Dec 29, 2020 | FRATTAROLI JOSEPH | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 22, 2020 | FRATTAROLI JOSEPH | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Dec 22, 2020 | Kalman Daniel | 10% Owner | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Dec 22, 2020 | Freeman Roy Lester | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Dec 22, 2020 | GRINT PAUL C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Dec 22, 2020 | BERMAN DENNIS N | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Dec 22, 2020 | O'Farrell Elizabeth G. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |