LEXICON PHARMACEUTICALS, INC. (LXRX)

Latest Insider Confidence Score

2026Q1

55.1
Bullish

Company insider confidence (by quarter)

2009Q1 2026Q1

Largest shareholders

Insider Role (last 12 mo) Shares held Filed at
Artal Participations S.a r.l. Director 136,180,481 Dec 16, 2024
Siren, L.L.C. Director 38,918,903 Jul 29, 2024
Invus Global Management, LLC Director 38,918,903 Jul 29, 2024
Artal International S.C.A. Director 38,918,903 May 14, 2024
Artal International Management S.A. Director 38,918,903 May 14, 2024

Recent buy/sell transactions

Exec date Filing date Insider Role Signal Confidence Shares % of shares Under plan? Amount (USD)
Feb 28, 2026 Mar 3, 2026 McDermott Wendy SVP, Human Resources Sell 42.5 -68,107 -19.68% ✗ $100.1K
Feb 28, 2026 Mar 3, 2026 Martens Rachel Yap SVP, Partnerships & Corp Strat Sell 42.5 -35,826 -53.40% ✗ $52.7K
Feb 28, 2026 Mar 3, 2026 Granowitz Craig B SVP, Chief Medical Officer Sell 42.5 -109,098 -25.22% ✗ $160.4K
Feb 28, 2026 Mar 3, 2026 Gopinathan Suma SVP, Discovery Sell 46.3 -24,338 -13.95% ✗ $35.8K
Feb 28, 2026 Mar 3, 2026 DeFrancesco Lisa SVP, IR and Corp Comm Sell 42.5 -74,572 -44.27% ✗ $109.6K
Feb 28, 2026 Mar 3, 2026 Crum Brian T SVP, General Counsel & Secr. Sell 42.5 -105,019 -19.67% ✗ $154.4K
Feb 28, 2026 Mar 3, 2026 Coiante Scott M CFO Sell 42.5 -54,881 -34.25% ✗ $80.7K
Feb 28, 2026 Mar 3, 2026 Exton Michael CEO Sell 40.0 -204,831 -40.70% ✗ $301.1K
Feb 25, 2026 Feb 27, 2026 DEBBANE RAYMOND Director Buy 47.5 +2,000 0.00% ✗ $3K
Feb 23, 2026 Feb 25, 2026 DEBBANE RAYMOND Director Buy 60.0 +100,000 0.19% ✗ $147K
Feb 19, 2026 Feb 23, 2026 DEBBANE RAYMOND Director Buy 65.0 +150,000 0.29% ✗ $219.8K
Feb 17, 2026 Feb 19, 2026 Artal Participations S.a r.l. Director Neutral 90.0 +41,289 11.25% ✗ -
Feb 13, 2026 Feb 18, 2026 DEBBANE RAYMOND Director Buy 75.0 +268,497 0.53% ✗ $352.9K
Feb 12, 2026 Feb 17, 2026 McDermott Wendy SVP, Human Resources Neutral 52.5 - 0.00% ✗ -
Feb 12, 2026 Feb 17, 2026 Martens Rachel Yap SVP, Partnerships & Corp Strat Neutral 52.5 - 0.00% ✗ -
Feb 12, 2026 Feb 17, 2026 Granowitz Craig B SVP, Chief Medical Officer Neutral 52.5 - 0.00% ✗ -
Feb 12, 2026 Feb 17, 2026 Gopinathan Suma SVP, Discovery Neutral 52.5 - 0.00% ✗ -
Feb 12, 2026 Feb 17, 2026 DeFrancesco Lisa SVP, IR and Corp Comm Neutral 52.5 - 0.00% ✗ -
Feb 12, 2026 Feb 17, 2026 Crum Brian T SVP, General Counsel & Secr. Neutral 52.5 - 0.00% ✗ -
Feb 12, 2026 Feb 17, 2026 Coiante Scott M CFO Neutral 52.5 - 0.00% ✗ -
Feb 12, 2026 Feb 17, 2026 Exton Michael CEO Neutral 52.5 - 0.00% ✗ -
Feb 12, 2026 Avicenna Life Sci Master Fund LP Director Neutral 52.5 - 0.00% ✗ -
Feb 2, 2026 Feb 4, 2026 Invus Global Management, LLC Director Buy 100.0 +24,305,607 17.40% ✗ $2M
Jun 9, 2025 Gopinathan Suma SVP, Discovery Neutral 52.5 - 0.00% ✗ -
Jun 6, 2025 Martens Rachel Yap VP, Partnerships & Corp Strat Neutral 52.5 - 0.00% ✗ -
Jun 3, 2025 Jun 3, 2025 Swain Judith L Director Neutral 52.5 - 0.00% ✗ -
Jun 3, 2025 Jun 3, 2025 Sullivan Diane E. Director Neutral 52.5 - 0.00% ✗ -
Jun 3, 2025 Jun 3, 2025 SOBECKI CHRISTOPHER J Director Neutral 52.5 - 0.00% ✗ -
Jun 3, 2025 Jun 3, 2025 Cheung Ivan Director Neutral 52.5 - 0.00% ✗ -
Jun 3, 2025 Jun 3, 2025 BARKER SAM L Director Neutral 52.5 - 0.00% ✗ -
Jun 3, 2025 Jun 3, 2025 Amouyal Philippe Director Neutral 52.5 - 0.00% ✗ -
Jun 3, 2025 Jun 3, 2025 DEBBANE RAYMOND Director Neutral 52.5 - 0.00% ✗ -
May 13, 2025 May 13, 2025 Swain Judith L Director Neutral 52.5 - 0.00% ✗ -
May 13, 2025 May 13, 2025 Sullivan Diane E. Director Neutral 52.5 - 0.00% ✗ -
May 13, 2025 May 13, 2025 SOBECKI CHRISTOPHER J Director Neutral 52.5 - 0.00% ✗ -
May 13, 2025 May 13, 2025 BARKER SAM L Director Neutral 52.5 - 0.00% ✗ -
May 13, 2025 May 13, 2025 Amouyal Philippe Director Neutral 52.5 - 0.00% ✗ -
May 13, 2025 May 13, 2025 DEBBANE RAYMOND Director Neutral 52.5 - 0.00% ✗ -
Feb 28, 2025 Mar 3, 2025 Alexander Kristen VP, Finance and Accounting Sell 46.3 -17,862 -18.96% ✗ $12K
Feb 28, 2025 Mar 3, 2025 McDermott Wendy SVP, Human Resources Sell 46.3 -30,004 -19.79% ✗ $20.1K
Feb 28, 2025 Mar 3, 2025 MAIN ALAN J EVP, Innov & Chem Sciences Sell 46.3 -43,434 -11.35% ✗ $29.1K
Feb 28, 2025 Mar 3, 2025 Granowitz Craig B SVP, Chief Medical Officer Sell 46.3 -65,308 -35.20% ✗ $43.8K
Feb 28, 2025 Mar 3, 2025 DeFrancesco Lisa SVP, IR and Corp Comm Sell 47.5 -9,096 -36.87% ✗ $6.1K
Feb 28, 2025 Mar 3, 2025 Crum Brian T SVP, General Counsel & Secr. Sell 46.3 -45,622 -14.89% ✗ $30.6K
Feb 13, 2025 Feb 18, 2025 Alexander Kristen VP, Finance and Accounting Neutral 52.5 - 0.00% ✗ -
Feb 13, 2025 Feb 18, 2025 McDermott Wendy SVP, Human Resources Neutral 52.5 - 0.00% ✗ -
Feb 13, 2025 Feb 18, 2025 MAIN ALAN J EVP, Innov & Chem Sciences Neutral 52.5 - 0.00% ✗ -
Feb 13, 2025 Feb 18, 2025 Granowitz Craig B SVP, Chief Medical Officer Neutral 52.5 - 0.00% ✗ -
Feb 13, 2025 Feb 18, 2025 DeFrancesco Lisa VP, IR and Corp Comm Neutral 52.5 - 0.00% ✗ -
Feb 13, 2025 Feb 18, 2025 Crum Brian T SVP, General Counsel & Secr. Neutral 52.5 - 0.00% ✗ -
Feb 13, 2025 Feb 18, 2025 Corrigan Brian SVP, Regulatory & QA Neutral 52.5 - 0.00% ✗ -
Feb 13, 2025 Feb 18, 2025 Coiante Scott M CFO Neutral 52.5 - 0.00% ✗ -
Feb 13, 2025 Feb 18, 2025 Exton Michael CEO Neutral 52.5 - 0.00% ✗ -
Jan 2, 2025 Jan 2, 2025 Coiante Scott M CFO Neutral 52.5 - 0.00% ✗ -
Jan 2, 2025 Coiante Scott M CFO Neutral 52.5 - 0.00% ✗ -
Dec 16, 2024 Artal Participations S.a r.l. Director Neutral 52.5 - 0.00% ✗ -
Dec 2, 2024 Dec 2, 2024 Cheung Ivan Director Neutral 52.5 - 0.00% ✗ -
Dec 2, 2024 Cheung Ivan Director Neutral 52.5 - 0.00% ✗ -
Oct 7, 2024 DeFrancesco Lisa VP, IR and Corp Strategy Neutral 52.5 - 0.00% ✗ -
Aug 12, 2024 Aug 12, 2024 Corrigan Brian SVP, Regulatory & QA Neutral 52.5 - 0.00% ✗ -
Aug 12, 2024 Corrigan Brian SVP, Regulatory & QA Neutral 52.5 - 0.00% ✗ -
Jul 29, 2024 Siren, L.L.C. Director Neutral 52.5 - 0.00% ✗ -
Jul 8, 2024 Jul 8, 2024 WADE JEFFREY L COO Neutral 52.5 - 0.00% ✗ -
Jul 8, 2024 Jul 8, 2024 Exton Michael CEO Neutral 52.5 - 0.00% ✗ -
Jul 8, 2024 Exton Michael CEO Neutral 52.5 - 0.00% ✗ -
May 10, 2024 May 14, 2024 Artal International S.C.A. Director Neutral 52.5 - 0.00% ✗ -
May 13, 2024 May 13, 2024 Swain Judith L Director Neutral 52.5 - 0.00% ✗ -
May 13, 2024 May 13, 2024 Sullivan Diane E. Director Neutral 52.5 - 0.00% ✗ -
May 13, 2024 May 13, 2024 SOBECKI CHRISTOPHER J Director Neutral 52.5 - 0.00% ✗ -
May 13, 2024 May 13, 2024 LEFKOWITZ ROBERT J MD Director Neutral 52.5 - 0.00% ✗ -
May 13, 2024 May 13, 2024 DEBBANE RAYMOND Director Neutral 52.5 - 0.00% ✗ -
May 13, 2024 May 13, 2024 BARKER SAM L Director Neutral 52.5 - 0.00% ✗ -
May 13, 2024 May 13, 2024 Amouyal Philippe Director Neutral 52.5 - 0.00% ✗ -
Apr 28, 2024 Apr 29, 2024 Swain Judith L Director Neutral 52.5 - 0.00% ✗ -
Apr 28, 2024 Apr 29, 2024 SOBECKI CHRISTOPHER J Director Neutral 52.5 - 0.00% ✗ -
Apr 28, 2024 Apr 29, 2024 LEFKOWITZ ROBERT J MD Director Neutral 52.5 - 0.00% ✗ -
Apr 28, 2024 Apr 29, 2024 DEBBANE RAYMOND Director Neutral 52.5 - 0.00% ✗ -
Apr 28, 2024 Apr 29, 2024 BARKER SAM L Director Neutral 52.5 - 0.00% ✗ -
Apr 28, 2024 Apr 29, 2024 Amouyal Philippe Director Neutral 52.5 - 0.00% ✗ -
Mar 13, 2024 Mar 13, 2024 Artal International S.C.A. Director Neutral 90.0 +1,150,922 100.00% ✗ -
Feb 28, 2024 Feb 29, 2024 Alexander Kristen VP, Finance and Accounting Sell 46.3 -11,793 -19.79% ✗ $30.9K
Feb 28, 2024 Feb 29, 2024 WADE JEFFREY L CFO Sell 42.5 -37,691 -10.41% ✗ $98.8K
Feb 28, 2024 Feb 29, 2024 McDermott Wendy VP, Human Resources Sell 42.5 -22,425 -29.85% ✗ $58.8K
Feb 28, 2024 Feb 29, 2024 MAIN ALAN J EVP, Innov & Chem Sciences Sell 42.5 -24,408 -8.71% ✗ $63.9K
Feb 28, 2024 Feb 29, 2024 Kassler-Taub Kenneth B. SVP, Regulatory & QA Sell 42.5 -24,353 -13.02% ✗ $63.8K
Feb 28, 2024 Feb 29, 2024 Granowitz Craig B SVP, Chief Medical Officer Sell 42.5 -31,265 -39.63% ✗ $81.9K
Feb 28, 2024 Feb 29, 2024 Crum Brian T SVP, General Counsel & Secr. Sell 42.5 -25,604 -12.61% ✗ $67.1K
Feb 28, 2024 Feb 29, 2024 COATS LONNEL CEO Sell 42.5 -61,371 -5.29% ✗ $160.8K
Feb 8, 2024 Feb 12, 2024 Alexander Kristen VP, Finance and Accounting Neutral 52.5 - 0.00% ✗ -
Feb 8, 2024 Feb 12, 2024 WADE JEFFREY L CFO Neutral 52.5 - 0.00% ✗ -
Feb 8, 2024 Feb 12, 2024 McDermott Wendy VP, Human Resources Neutral 52.5 - 0.00% ✗ -
Feb 8, 2024 Feb 12, 2024 MAIN ALAN J EVP, Innov & Chem Sciences Neutral 52.5 - 0.00% ✗ -
Feb 8, 2024 Feb 12, 2024 Kassler-Taub Kenneth B. SVP, Regulatory & QA Neutral 52.5 - 0.00% ✗ -
Feb 8, 2024 Feb 12, 2024 Granowitz Craig B SVP, Chief Medical Officer Neutral 52.5 - 0.00% ✗ -
Feb 8, 2024 Feb 12, 2024 Garner Thomas SVP, Chief Commercial Officer Neutral 52.5 - 0.00% ✗ -
Feb 8, 2024 Feb 12, 2024 Crum Brian T SVP, General Counsel & Secr. Neutral 52.5 - 0.00% ✗ -
Feb 8, 2024 Feb 12, 2024 COATS LONNEL CEO Neutral 52.5 - 0.00% ✗ -
Nov 16, 2023 Nov 17, 2023 COATS LONNEL CEO Buy 95.0 +90,000 10.92% ✗ $94.8K
Nov 13, 2023 Nov 14, 2023 Amouyal Philippe Director Buy 95.0 +200,000 495.88% ✗ $201.5K
Nov 10, 2023 Nov 13, 2023 COATS LONNEL CEO Buy 78.8 +10,000 1.23% ✗ $10.1K