2026Q1
| Insider | Role (last 12 mo) | Shares held | Filed at |
|---|---|---|---|
| Novo A/S | 10% Owner | 1,712,811 | Jul 16, 2020 |
| New Enterprise Associates 15, L.P. | 10% Owner | 1,712,810 | Jul 16, 2020 |
| NEA Partners 15, L.P. | 10% Owner | 1,712,810 | Jul 16, 2020 |
| Nea 15 Gp, Llc | 10% Owner | 1,712,810 | Jul 16, 2020 |
| Sandell Scott D | 10% Owner | 1,712,810 | Jul 16, 2020 |
| Exec date | Filing date | Insider | Role | Signal | Confidence | Shares | % of shares | Under plan? | Amount (USD) |
|---|---|---|---|---|---|---|---|---|---|
| Jan 15, 2026 | Jan 20, 2026 | HASTINGS PAUL J | CEO | Sell | 42.5 | -26,046 | -6.26% | ✗ | $53.9K |
| Jan 15, 2026 | Jan 20, 2026 | Mahmood Nadir | President | Sell | 46.3 | -5,649 | -3.26% | ✗ | $11.7K |
| Jan 6, 2026 | Jan 8, 2026 | Rose Shawn Marshall | Officer | Neutral | 90.0 | +70,000 | 100.00% | ✗ | - |
| Jan 6, 2026 | Jan 8, 2026 | Mahmood Nadir | President | Neutral | 90.0 | +80,000 | 85.68% | ✗ | - |
| Jan 6, 2026 | Jan 8, 2026 | HASTINGS PAUL J | CEO | Neutral | 90.0 | +94,000 | 29.19% | ✗ | - |
| Jun 23, 2025 | Jun 25, 2025 | Rose Shawn Marshall | Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 25, 2025 | Rose Shawn Marshall | Officer | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jun 18, 2025 | Jun 20, 2025 | HASTINGS PAUL J | CEO | Sell | 50.0 | -1,790 | -0.56% | ✗ | $3.2K |
| Jun 5, 2025 | Jun 9, 2025 | George Simeon | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 9, 2025 | Behbahani Ali | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 9, 2025 | RA CAPITAL MANAGEMENT, L.P. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 9, 2025 | Mahmood Nadir | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 9, 2025 | HASTINGS PAUL J | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 9, 2025 | Vratsanos George | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 9, 2025 | Thedinga Angela | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 9, 2025 | Scheiner Zachary | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 9, 2025 | PATTERSON LEONE D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 9, 2025 | Dybbs Michael | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 15, 2025 | Jan 17, 2025 | Shook David | Officer | Sell | 46.3 | -8,638 | -4.33% | ✗ | $19K |
| Jan 15, 2025 | Jan 17, 2025 | Levin Alyssa | Officer | Sell | 46.3 | -5,838 | -5.38% | ✗ | $12.8K |
| Jan 15, 2025 | Jan 17, 2025 | Brandenberger Ralph | Chief Technical Officer | Sell | 46.3 | -7,447 | -5.63% | ✗ | $16.4K |
| Jan 15, 2025 | Jan 17, 2025 | HASTINGS PAUL J | CEO | Sell | 46.3 | -17,378 | -5.15% | ✗ | $38.2K |
| Jan 15, 2025 | Jan 17, 2025 | Hager Alicia J. | Chief Legal Officer | Sell | 46.3 | -9,584 | -6.13% | ✗ | $21.1K |
| Jan 3, 2025 | Jan 7, 2025 | Levin Alyssa | Officer | Neutral | 90.0 | +52,500 | 93.75% | ✗ | - |
| Jan 3, 2025 | Jan 7, 2025 | Brandenberger Ralph | Chief Technical Officer | Neutral | 90.0 | +52,500 | 65.84% | ✗ | - |
| Jan 3, 2025 | Jan 7, 2025 | Hager Alicia J. | Chief Legal Officer | Neutral | 90.0 | +52,500 | 50.57% | ✗ | - |
| Jan 3, 2025 | Jan 7, 2025 | Shook David | Officer | Neutral | 90.0 | +59,000 | 41.97% | ✗ | - |
| Jan 3, 2025 | Jan 7, 2025 | Mahmood Nadir | President | Neutral | 90.0 | +62,000 | 197.60% | ✗ | - |
| Jan 3, 2025 | Jan 7, 2025 | HASTINGS PAUL J | CEO | Neutral | 90.0 | +94,500 | 38.93% | ✗ | - |
| Aug 21, 2024 | Aug 23, 2024 | Shook David | Officer | Neutral | 50.0 | -1,352 | -0.97% | ✗ | - |
| Jul 29, 2024 | Jul 31, 2024 | Mahmood Nadir | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 31, 2024 | Mahmood Nadir | President | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jul 15, 2024 | Jul 31, 2024 | Shook David | Officer | Neutral | 90.0 | +23,421 | 20.10% | ✗ | - |
| Jul 16, 2024 | Jul 18, 2024 | Hager Alicia J. | Chief Legal Officer | Sell | 41.3 | -3,396 | -3.17% | ✓ | $27.2K |
| Jun 18, 2024 | Jun 20, 2024 | Trager James | Chief Scientific Officer | Sell | 52.5 | -456 | -0.30% | ✗ | $2.6K |
| Jun 18, 2024 | Jun 20, 2024 | HASTINGS PAUL J | CEO | Sell | 50.0 | -1,770 | -0.73% | ✗ | $9.9K |
| Jun 18, 2024 | Jun 20, 2024 | Shook David | Chief Medical Officer | Sell | 52.5 | -456 | -0.39% | ✗ | $2.6K |
| Jun 18, 2024 | Jun 20, 2024 | Hager Alicia J. | Chief Legal Officer | Sell | 50.0 | -727 | -0.67% | ✗ | $4.1K |
| Jun 18, 2024 | Jun 20, 2024 | Brandenberger Ralph | Chief Technical Officer | Sell | 52.5 | -229 | -0.29% | ✗ | $1.3K |
| Jun 13, 2024 | Jun 14, 2024 | George Simeon | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 13, 2024 | Jun 14, 2024 | Behbahani Ali | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 13, 2024 | Jun 14, 2024 | RA CAPITAL MANAGEMENT, L.P. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 13, 2024 | Jun 14, 2024 | Scheiner Zachary | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 13, 2024 | Jun 14, 2024 | PATTERSON LEONE D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 13, 2024 | Jun 14, 2024 | Dybbs Michael | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 13, 2024 | Jun 14, 2024 | Thedinga Angela | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 13, 2024 | Jun 14, 2024 | Vratsanos George | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 14, 2024 | Vratsanos George | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 27, 2024 | Mar 29, 2024 | RA CAPITAL MANAGEMENT, L.P. | Director | Buy | 100.0 | +3,000,000 | 42.55% | ✗ | $30M |
| Mar 27, 2024 | Mar 28, 2024 | George Simeon | Director | Buy | 100.0 | +2,000,000 | 150.00% | ✗ | $20M |
| Mar 1, 2024 | Mar 5, 2024 | HASTINGS PAUL J | CEO | Sell | 5.0 | -150,000 | -38.41% | ✓ | $2M |
| Mar 1, 2024 | Mar 5, 2024 | Brandenberger Ralph | Chief Technical Officer | Sell | 28.8 | -8,367 | -9.47% | ✓ | $104.7K |
| Feb 12, 2024 | Feb 14, 2024 | Trager James | Chief Scientific Officer | Sell | 45.0 | -4,143 | -2.70% | ✓ | $49.7K |
| Jan 16, 2024 | Jan 18, 2024 | Shook David | Chief Medical Officer | Sell | 46.3 | -3,552 | -3.00% | ✗ | $31K |
| Jan 16, 2024 | Jan 18, 2024 | Trager James | Chief Scientific Officer | Sell | 46.3 | -4,560 | -2.88% | ✗ | $39.9K |
| Jan 16, 2024 | Jan 18, 2024 | Brandenberger Ralph | Chief Technical Officer | Sell | 46.3 | -2,512 | -2.99% | ✗ | $22K |
| Jan 16, 2024 | Jan 18, 2024 | HASTINGS PAUL J | CEO | Sell | 42.5 | -9,697 | -2.42% | ✗ | $84.8K |
| Jan 16, 2024 | Jan 18, 2024 | Hager Alicia J. | Chief Legal Officer | Sell | 46.3 | -4,554 | -4.05% | ✗ | $39.8K |
| Jan 4, 2024 | Jan 8, 2024 | Shook David | Chief Medical Officer | Neutral | 90.0 | +56,000 | 89.55% | ✗ | - |
| Jan 4, 2024 | Jan 8, 2024 | Brandenberger Ralph | Chief Technical Officer | Neutral | 90.0 | +56,000 | 199.37% | ✗ | - |
| Jan 4, 2024 | Jan 8, 2024 | Trager James | Chief Scientific Officer | Neutral | 90.0 | +56,000 | 54.84% | ✗ | - |
| Jan 4, 2024 | Jan 8, 2024 | HASTINGS PAUL J | CEO | Neutral | 90.0 | +85,000 | 26.97% | ✗ | - |
| Jan 4, 2024 | Jan 8, 2024 | Levin Alyssa | Officer | Neutral | 90.0 | +56,000 | 100.00% | ✗ | - |
| Jan 4, 2024 | Jan 8, 2024 | Hager Alicia J. | Chief Legal Officer | Neutral | 90.0 | +56,000 | 99.12% | ✗ | - |
| Aug 21, 2023 | Aug 23, 2023 | Shook David | Chief Medical Officer | Sell | 47.5 | -1,331 | -2.15% | ✗ | $2.4K |
| Jul 1, 2023 | Jul 5, 2023 | Levin Alyssa | Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 5, 2023 | Levin Alyssa | Officer | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jul 1, 2023 | Jul 5, 2023 | Shook David | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 20, 2023 | Jun 22, 2023 | Trager James | Chief Scientific Officer | Sell | 52.5 | -439 | -0.44% | ✗ | $2.1K |
| Jun 20, 2023 | Jun 22, 2023 | Brandenberger Ralph | Chief Technical Officer | Sell | 50.0 | -221 | -0.78% | ✗ | $1.1K |
| Jun 20, 2023 | Jun 22, 2023 | Hager Alicia J. | Chief Legal Officer | Sell | 47.5 | -701 | -1.23% | ✗ | $3.4K |
| Jun 20, 2023 | Jun 22, 2023 | Shook David | Chief Medical Officer | Sell | 50.0 | -439 | -0.70% | ✗ | $2.1K |
| Jun 20, 2023 | Jun 22, 2023 | Mahmood Nadir | Officer | Sell | 50.0 | -526 | -0.61% | ✗ | $2.6K |
| Jun 20, 2023 | Jun 22, 2023 | HASTINGS PAUL J | CEO | Sell | 50.0 | -1,704 | -0.54% | ✗ | $8.3K |
| Jun 7, 2023 | Jun 9, 2023 | George Simeon | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 7, 2023 | Jun 9, 2023 | Behbahani Ali | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 7, 2023 | Jun 9, 2023 | RA CAPITAL MANAGEMENT, L.P. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 7, 2023 | Jun 9, 2023 | Thedinga Angela | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 7, 2023 | Jun 9, 2023 | PATTERSON LEONE D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 7, 2023 | Jun 9, 2023 | Dybbs Michael | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 7, 2023 | Jun 9, 2023 | Azzam Fouad Oscar | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 7, 2023 | Jun 9, 2023 | Scheiner Zachary | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 13, 2023 | Jan 18, 2023 | Trager James | Chief Scientific Officer | Sell | 90.0 | +36,385 | 58.52% | ✗ | $6.1K |
| Jan 13, 2023 | Jan 18, 2023 | Shook David | Chief Medical Officer | Sell | 90.0 | +37,325 | 162.45% | ✗ | $960.8 |
| Jan 13, 2023 | Jan 18, 2023 | Mahmood Nadir | Officer | Sell | 90.0 | +36,378 | 75.91% | ✗ | $6.2K |
| Jan 13, 2023 | Jan 18, 2023 | HASTINGS PAUL J | CEO | Sell | 91.3 | +60,809 | 24.10% | ✗ | $20.3K |
| Jan 13, 2023 | Jan 18, 2023 | Hager Alicia J. | Chief Legal Officer | Sell | 90.0 | +36,397 | 174.99% | ✗ | $6.1K |
| Jan 13, 2023 | Jan 18, 2023 | Brandenberger Ralph | Chief Technical Officer | Sell | 90.0 | +20,509 | 262.94% | ✗ | $2.7K |
| Jan 10, 2023 | Shook David | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Oct 6, 2022 | Oct 7, 2022 | Brandenberger Ralph | Chief Technical Officer | Sell | 32.5 | -842 | -9.74% | ✓ | $11.8K |
| Sep 28, 2022 | Sep 30, 2022 | HASTINGS PAUL J | CEO | Sell | 26.3 | -23,874 | -8.70% | ✓ | $311.1K |
| Sep 21, 2022 | Sep 22, 2022 | HASTINGS PAUL J | CEO | Sell | 41.3 | -6,126 | -2.18% | ✓ | $79.7K |
| Aug 15, 2022 | Aug 17, 2022 | Trager James | Chief Scientific Officer | Sell | 32.5 | -5,000 | -7.44% | ✓ | $87.7K |
| Aug 15, 2022 | Aug 17, 2022 | Brandenberger Ralph | Chief Technical Officer | Sell | 10.0 | -11,000 | -58.51% | ✓ | $194.1K |
| Aug 15, 2022 | Aug 17, 2022 | Mahmood Nadir | Officer | Sell | 25.0 | -7,500 | -14.00% | ✓ | $135.2K |
| Aug 8, 2022 | Aug 10, 2022 | Brandenberger Ralph | Chief Technical Officer | Sell | 10.0 | -11,593 | -59.78% | ✓ | $179.8K |
| Aug 8, 2022 | Aug 10, 2022 | Mahmood Nadir | Officer | Sell | 25.0 | -7,500 | -14.00% | ✓ | $114.9K |
| Jul 25, 2022 | Jul 26, 2022 | Brandenberger Ralph | Chief Technical Officer | Sell | 13.8 | -3,000 | -27.78% | ✓ | $40.2K |
| Jul 25, 2022 | Jul 26, 2022 | Mahmood Nadir | Officer | Sell | 25.0 | -7,500 | -14.00% | ✓ | $100.5K |
| Jul 15, 2022 | Jul 18, 2022 | Brandenberger Ralph | Chief Technical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |