2025Q4
| Insider | Role (last 12 mo) | Shares held | Filed at |
|---|---|---|---|
| Frost Phillip Md Et Al | CEO | 33,696,128 | Nov 21, 2025 |
| Frost Gamma Investments Trust | 10% Owner | 33,696,128 | Nov 21, 2025 |
| Hsiao Jane Ph D | Chair | 27,599,870 | Aug 10, 2021 |
| Zerhouni Elias A. | Chair | 19,777,514 | Jun 22, 2022 |
| Rubin Steven D | Executive VP-Administration | 6,625,232 | Jul 26, 2024 |
| Exec date | Filing date | Insider | Role | Signal | Confidence | Shares | % of shares | Under plan? | Amount (USD) |
|---|---|---|---|---|---|---|---|---|---|
| Nov 21, 2025 | Nov 21, 2025 | FROST PHILLIP MD ET AL | CEO | Buy | 67.5 | +580,000 | 0.26% | ✗ | $768.8K |
| Nov 20, 2025 | Nov 20, 2025 | FROST PHILLIP MD ET AL | CEO | Buy | 67.5 | +580,000 | 0.26% | ✗ | $771.3K |
| Nov 19, 2025 | Nov 19, 2025 | FROST PHILLIP MD ET AL | CEO | Buy | 67.5 | +580,000 | 0.27% | ✗ | $759.1K |
| Nov 18, 2025 | Nov 18, 2025 | FROST PHILLIP MD ET AL | CEO | Buy | 67.5 | +580,000 | 0.27% | ✗ | $678.9K |
| Oct 31, 2025 | Oct 31, 2025 | FROST PHILLIP MD ET AL | CEO | Buy | 60.0 | +150,000 | 0.07% | ✗ | $213.4K |
| Aug 18, 2025 | Aug 19, 2025 | FROST PHILLIP MD ET AL | CEO | Neutral | 45.0 | -440,000 | -0.20% | ✗ | - |
| Aug 8, 2025 | Aug 8, 2025 | FROST PHILLIP MD ET AL | CEO | Buy | 67.5 | +675,000 | 0.31% | ✗ | $891K |
| May 27, 2025 | May 29, 2025 | FROST PHILLIP MD ET AL | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 27, 2025 | May 29, 2025 | HSIAO JANE PH D | Chair | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 27, 2025 | May 29, 2025 | Zerhouni Elias A. | Chair | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 27, 2025 | May 29, 2025 | Rubin Steven D | Executive VP-Administration | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 27, 2025 | May 29, 2025 | Logal Adam | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 27, 2025 | May 29, 2025 | Nabel Gary J. | Chief Innovation Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 23, 2025 | Apr 23, 2025 | KRASNO RICHARD M | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 23, 2025 | Apr 23, 2025 | Lachman Prem A | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 23, 2025 | Apr 23, 2025 | MEDEL ROGER MD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 23, 2025 | Apr 23, 2025 | PAGANELLI JOHN A | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 23, 2025 | Apr 23, 2025 | PFENNIGER RICHARD C JR | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 23, 2025 | Apr 23, 2025 | Yu Alice Lin-Tsing | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 10, 2025 | Apr 10, 2025 | FROST PHILLIP MD ET AL | CEO | Buy | 60.0 | +125,000 | 0.06% | ✗ | $169.7K |
| Apr 8, 2025 | Apr 8, 2025 | FROST PHILLIP MD ET AL | CEO | Buy | 60.0 | +125,000 | 0.06% | ✗ | $184.7K |
| Apr 1, 2025 | Apr 1, 2025 | FROST PHILLIP MD ET AL | CEO | Buy | 52.5 | +100,000 | 0.05% | ✗ | $164.9K |
| Mar 28, 2025 | Mar 28, 2025 | FROST PHILLIP MD ET AL | CEO | Buy | 62.5 | +150,000 | 0.07% | ✗ | $254.4K |
| Mar 17, 2025 | Mar 17, 2025 | FROST PHILLIP MD ET AL | CEO | Buy | 62.5 | +200,000 | 0.09% | ✗ | $347.8K |
| Mar 4, 2025 | Mar 4, 2025 | FROST PHILLIP MD ET AL | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 3, 2025 | Mar 3, 2025 | FROST PHILLIP MD ET AL | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 28, 2025 | Feb 28, 2025 | FROST PHILLIP MD ET AL | CEO | Buy | 52.5 | +67,434 | 0.03% | ✗ | $115.3K |
| Jan 28, 2025 | Jan 28, 2025 | FROST PHILLIP MD ET AL | CEO | Buy | 52.5 | +47,537 | 0.02% | ✗ | $70.1K |
| Jan 17, 2025 | Jan 17, 2025 | FROST PHILLIP MD ET AL | CEO | Buy | 60.0 | +150,000 | 0.07% | ✗ | $220.4K |
| Jan 15, 2025 | Jan 15, 2025 | FROST PHILLIP MD ET AL | CEO | Buy | 67.5 | +500,000 | 0.23% | ✗ | $740.9K |
| Dec 13, 2024 | Dec 13, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 60.0 | +125,000 | 0.06% | ✗ | $199.4K |
| Dec 11, 2024 | Dec 11, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 67.5 | +500,000 | 0.23% | ✗ | $781.1K |
| Nov 29, 2024 | Nov 29, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 62.5 | +199,072 | 0.09% | ✗ | $305.4K |
| Nov 22, 2024 | Nov 22, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 52.5 | +100,000 | 0.05% | ✗ | $159K |
| Nov 8, 2024 | Nov 20, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 62.5 | +280,183 | 0.13% | ✗ | $421.5K |
| Nov 14, 2024 | Nov 14, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 52.5 | +100,000 | 0.05% | ✗ | $162K |
| Nov 8, 2024 | Nov 8, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 62.5 | +280,183 | 0.13% | ✗ | $421.5K |
| Sep 27, 2024 | Sep 27, 2024 | FROST PHILLIP MD ET AL | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 25, 2024 | Sep 27, 2024 | FROST PHILLIP MD ET AL | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 25, 2024 | Sep 26, 2024 | FROST PHILLIP MD ET AL | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 24, 2024 | Jul 26, 2024 | FROST PHILLIP MD ET AL | CEO | Neutral | 60.0 | +500,000 | 0.20% | ✗ | - |
| Jul 24, 2024 | Jul 26, 2024 | HSIAO JANE PH D | Chair | Neutral | 77.5 | +500,000 | 1.51% | ✗ | - |
| Jul 24, 2024 | Jul 26, 2024 | Logal Adam | CFO | Neutral | 90.0 | +437,500 | 244.19% | ✗ | - |
| Jul 24, 2024 | Jul 26, 2024 | Rubin Steven D | Executive VP-Administration | Neutral | 85.0 | +437,500 | 7.07% | ✗ | - |
| Jul 24, 2024 | Jul 26, 2024 | Zerhouni Elias A. | Chair | Neutral | 77.5 | +500,000 | 1.24% | ✗ | - |
| Jul 24, 2024 | Jul 26, 2024 | Nabel Gary J. | Chief Innovation Officer | Neutral | 77.5 | +437,500 | 2.11% | ✗ | - |
| May 23, 2024 | May 23, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 52.5 | +100,000 | 0.05% | ✗ | $126.9K |
| May 17, 2024 | May 17, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 60.0 | +163,997 | 0.08% | ✗ | $211.2K |
| Mar 29, 2024 | Yu Alice Lin-Tsing | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 29, 2024 | PAGANELLI JOHN A | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 29, 2024 | Lachman Prem A | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 29, 2024 | PFENNIGER RICHARD C JR | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 29, 2024 | KRASNO RICHARD M | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 29, 2024 | MEDEL ROGER MD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 18, 2024 | Mar 18, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 67.5 | +500,000 | 0.23% | ✗ | $437.1K |
| Mar 14, 2024 | Mar 14, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 67.5 | +500,000 | 0.23% | ✗ | $444.3K |
| Mar 13, 2024 | Mar 13, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 67.5 | +500,000 | 0.24% | ✗ | $463.8K |
| Mar 12, 2024 | Mar 12, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 67.5 | +600,000 | 0.28% | ✗ | $559.4K |
| Feb 28, 2024 | Feb 28, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 67.5 | +500,000 | 0.24% | ✗ | $496.2K |
| Feb 21, 2024 | Feb 21, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 67.5 | +1,000,000 | 0.48% | ✗ | $991.7K |
| Feb 7, 2024 | Feb 7, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 77.5 | +1,500,000 | 0.72% | ✗ | $1.5M |
| Jan 29, 2024 | Jan 29, 2024 | KRASNO RICHARD M | Director | Buy | 91.3 | +30,000 | 40.91% | ✗ | $29.8K |
| Jan 19, 2024 | Jan 19, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 67.5 | +500,000 | 0.24% | ✗ | $488.7K |
| Jan 18, 2024 | Jan 18, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 62.5 | +400,000 | 0.19% | ✗ | $386.2K |
| Jan 17, 2024 | Jan 17, 2024 | HSIAO JANE PH D | Chair | Buy | 65.0 | +150,000 | 0.45% | ✗ | $142.5K |
| Jan 16, 2024 | Jan 16, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 67.5 | +1,000,000 | 0.48% | ✗ | $954.3K |
| Jan 11, 2024 | Jan 11, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 67.5 | +511,531 | 0.22% | ✗ | $480.4K |
| Jan 8, 2024 | Jan 10, 2024 | Nabel Gary J. | Chief Innovation Officer | Buy | 95.0 | +216,184 | 42.74% | ✗ | $200.4K |
| Jan 5, 2024 | Jan 8, 2024 | HSIAO JANE PH D | Chair | Buy | 65.0 | +150,010 | 0.46% | ✗ | $130.9K |
| Jan 5, 2024 | Jan 8, 2024 | FROST PHILLIP MD ET AL | CEO | Buy | 77.5 | +1,500,000 | 0.73% | ✗ | $1.3M |
| Jan 5, 2024 | Jan 5, 2024 | Zerhouni Elias A. | Chair | Buy | 90.0 | +550,300 | 2.77% | ✗ | $514.1K |
| Jan 5, 2024 | Jan 5, 2024 | PAGANELLI JOHN A | Director | Buy | 86.3 | +25,000 | 6.78% | ✗ | $22.1K |
| Jan 5, 2024 | Jan 5, 2024 | Rubin Steven D | Executive VP-Administration | Buy | 55.0 | +10,000 | 0.16% | ✗ | $8.7K |
| Jan 5, 2024 | Jan 5, 2024 | PFENNIGER RICHARD C JR | Director | Buy | 86.3 | +25,000 | 8.33% | ✗ | $23.4K |
| Nov 13, 2023 | Nov 14, 2023 | PFENNIGER RICHARD C JR | Director | Buy | 86.3 | +25,000 | 9.09% | ✗ | $32.5K |
| Nov 9, 2023 | Nov 13, 2023 | FROST PHILLIP MD ET AL | CEO | Buy | 70.0 | +1,000,000 | 0.49% | ✗ | $1.3M |
| Nov 10, 2023 | Nov 13, 2023 | HSIAO JANE PH D | Chair | Buy | 65.0 | +100,000 | 0.31% | ✗ | $126.7K |
| Nov 10, 2023 | Nov 13, 2023 | Rubin Steven D | Executive VP-Administration | Buy | 56.3 | +10,000 | 0.16% | ✗ | $13K |
| Aug 17, 2023 | Aug 18, 2023 | FROST PHILLIP MD ET AL | CEO | Buy | 52.5 | +100,000 | 0.05% | ✗ | $175.8K |
| Aug 14, 2023 | Aug 15, 2023 | FROST PHILLIP MD ET AL | CEO | Buy | 52.5 | +75,000 | 0.04% | ✗ | $131.3K |
| Aug 9, 2023 | Aug 10, 2023 | FROST PHILLIP MD ET AL | CEO | Buy | 52.5 | +100,000 | 0.05% | ✗ | $181.8K |
| Aug 7, 2023 | Aug 8, 2023 | FROST PHILLIP MD ET AL | CEO | Buy | 70.0 | +650,000 | 0.32% | ✗ | $1.2M |
| Jun 22, 2023 | Jun 23, 2023 | Yu Alice Lin-Tsing | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 22, 2023 | Jun 23, 2023 | PFENNIGER RICHARD C JR | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 22, 2023 | Jun 23, 2023 | PAGANELLI JOHN A | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 22, 2023 | Jun 23, 2023 | MEDEL ROGER MD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 22, 2023 | Jun 23, 2023 | Lachman Prem A | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 22, 2023 | Jun 23, 2023 | KRASNO RICHARD M | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 22, 2023 | Jun 23, 2023 | Borisy Alexis | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 18, 2023 | May 19, 2023 | FROST PHILLIP MD ET AL | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 18, 2023 | May 19, 2023 | HSIAO JANE PH D | Chair | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 18, 2023 | May 19, 2023 | Zerhouni Elias A. | Chair | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 18, 2023 | May 19, 2023 | Rubin Steven D | Executive VP-Administration | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 18, 2023 | May 19, 2023 | Logal Adam | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 18, 2023 | May 19, 2023 | Nabel Gary J. | Chief Innovation Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 5, 2023 | May 8, 2023 | Nabel Gary J. | Chief Innovation Officer | Buy | 75.0 | +460,245 | 0.76% | ✗ | $840.9K |
| Mar 22, 2023 | Mar 23, 2023 | FROST PHILLIP MD ET AL | CEO | Buy | 62.5 | +200,000 | 0.10% | ✗ | $264.3K |
| Mar 8, 2023 | Mar 9, 2023 | FROST PHILLIP MD ET AL | CEO | Buy | 70.0 | +1,000,000 | 0.50% | ✗ | $1.2M |
| Feb 10, 2023 | Feb 14, 2023 | FROST PHILLIP MD ET AL | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 10, 2023 | Feb 14, 2023 | HSIAO JANE PH D | Chair | Neutral | 52.5 | - | 0.00% | ✗ | - |