Prime Medicine, Inc. (PRME)

Latest Insider Confidence Score

2026Q1

54.3
Bullish

Company insider confidence (by quarter)

2022Q4 2026Q1

Largest shareholders

Insider Role (last 12 mo) Shares held Filed at
Liu David R. 10% Owner 20,240,945 Jul 1, 2025
Gottesdiener Keith Michael — 4,361,078 Oct 19, 2022
Cahill Thomas Director 1,689,005 Oct 26, 2022
Duffield Jeremy — 965,001 Oct 19, 2022
Fmr Llc — 423,509 Oct 26, 2022

Recent buy/sell transactions

Exec date Filing date Insider Role Signal Confidence Shares % of shares Under plan? Amount (USD)
Feb 26, 2026 Feb 27, 2026 Reine Allan CEO Neutral 52.5 - 0.00% ✗ -
Feb 23, 2026 Feb 24, 2026 LEE ANN L. Chief Technical Officer Neutral 52.5 - 0.00% ✗ -
Feb 23, 2026 Feb 24, 2026 Alenson Carman Officer Neutral 52.5 - 0.00% ✗ -
Aug 1, 2025 Aug 5, 2025 LEE ANN L. Chief Technical Officer Neutral 52.5 - 0.00% ✗ -
Aug 1, 2025 Aug 5, 2025 Schenkein David P Director Neutral 52.5 - 0.00% ✗ -
Aug 1, 2025 Aug 5, 2025 NELSEN ROBERT Director Neutral 52.5 - 0.00% ✗ -
Aug 1, 2025 Aug 5, 2025 Marrazzo Jeffrey D Director Neutral 52.5 - 0.00% ✗ -
Aug 1, 2025 Aug 5, 2025 Kelly Michael Aaron Director Neutral 52.5 - 0.00% ✗ -
Aug 1, 2025 Aug 5, 2025 Foster-Cheek Kaye I Director Neutral 52.5 - 0.00% ✗ -
Aug 1, 2025 Aug 5, 2025 Chung Wendy Director Neutral 52.5 - 0.00% ✗ -
Aug 1, 2025 Aug 5, 2025 Cahill Thomas Director Neutral 52.5 - 0.00% ✗ -
Aug 1, 2025 Aug 5, 2025 Reine Allan CEO Neutral 52.5 - 0.00% ✗ -
Aug 1, 2025 Aug 5, 2025 Alenson Carman Officer Neutral 52.5 - 0.00% ✗ -
Aug 1, 2025 Aug 1, 2025 NELSEN ROBERT Director Buy 100.0 +3,030,300 19.58% ✗ $10M
Aug 1, 2025 Aug 1, 2025 ARCH Venture Partners XII, LLC 10% Owner Buy 100.0 +3,030,300 19.61% ✗ $10M
Aug 1, 2025 Aug 1, 2025 ARCH Venture Partners X, LLC 10% Owner Buy 100.0 +3,030,300 19.61% ✗ $10M
Jun 30, 2025 Jul 1, 2025 Liu David R. 10% Owner Buy 60.0 +21,000 0.10% ✓ $52.8K
Jun 23, 2025 Jun 23, 2025 Liu David R. 10% Owner Buy 56.3 +21,000 0.10% ✓ $45.4K
Jun 16, 2025 Jun 16, 2025 Liu David R. 10% Owner Buy 56.3 +21,000 0.10% ✓ $31.2K
Jun 11, 2025 Jun 12, 2025 Liu David R. 10% Owner Buy 56.3 +21,000 0.10% ✓ $33.6K
Jun 4, 2025 Jun 5, 2025 Schenkein David P Director Neutral 52.5 - 0.00% ✗ -
Jun 4, 2025 Jun 5, 2025 Marrazzo Jeffrey D Director Neutral 52.5 - 0.00% ✗ -
Jun 4, 2025 Jun 5, 2025 NELSEN ROBERT Director Neutral 52.5 - 0.00% ✗ -
Jun 4, 2025 Jun 5, 2025 Kelly Michael Aaron Director Neutral 52.5 - 0.00% ✗ -
Jun 4, 2025 Jun 5, 2025 Foster-Cheek Kaye I Director Neutral 52.5 - 0.00% ✗ -
Jun 4, 2025 Jun 5, 2025 Chung Wendy Director Neutral 52.5 - 0.00% ✗ -
Jun 4, 2025 Jun 5, 2025 Cahill Thomas Director Neutral 52.5 - 0.00% ✗ -
May 20, 2025 May 22, 2025 Brudnick Richard Chief Business Officer Buy 91.3 +20,000 100.00% ✗ $23.8K
May 21, 2025 May 22, 2025 LEE ANN L. Chief Technical Officer Buy 95.0 +100,000 100.00% ✗ $113K
May 21, 2025 May 22, 2025 Reine Allan CEO Buy 95.0 +125,000 100.00% ✗ $147.2K
May 19, 2025 May 19, 2025 Marrazzo Jeffrey D Director Neutral 52.5 - 0.00% ✗ -
May 19, 2025 May 19, 2025 Reine Allan CEO Neutral 52.5 - 0.00% ✗ -
May 8, 2025 May 12, 2025 Reine Allan CFO Neutral 52.5 - 0.00% ✗ -
May 8, 2025 May 12, 2025 Gottesdiener Keith Michael Officer Neutral 52.5 - 0.00% ✗ -
May 8, 2025 May 12, 2025 LEE ANN L. Chief Technical Officer Neutral 52.5 - 0.00% ✗ -
Feb 28, 2025 Mar 4, 2025 Gottesdiener Keith Michael Officer Neutral 52.5 - 0.00% ✗ -
Feb 27, 2025 Mar 3, 2025 Alenson Carman Officer Neutral 52.5 - 0.00% ✗ -
Feb 27, 2025 Mar 3, 2025 Goldwasser Meredith SVP, Strategy & Corporate Ops. Neutral 52.5 - 0.00% ✗ -
Feb 27, 2025 Mar 3, 2025 Duffield Jeremy Chief Scientific Officer Neutral 52.5 - 0.00% ✗ -
Feb 27, 2025 Mar 3, 2025 LEE ANN L. Chief Technical Officer Neutral 52.5 - 0.00% ✗ -
Feb 27, 2025 Mar 3, 2025 Brudnick Richard Chief Business Officer Neutral 52.5 - 0.00% ✗ -
Feb 27, 2025 Mar 3, 2025 Reine Allan CFO Neutral 52.5 - 0.00% ✗ -
Dec 5, 2024 Dec 9, 2024 Gottesdiener Keith Michael Officer Neutral 52.5 - 0.00% ✗ -
Dec 5, 2024 Dec 9, 2024 Brudnick Richard Chief Business Officer Neutral 52.5 - 0.00% ✗ -
Dec 5, 2024 Dec 9, 2024 Reine Allan CFO Neutral 52.5 - 0.00% ✗ -
Oct 8, 2024 Oct 10, 2024 Gottesdiener Keith Michael Officer Neutral 52.5 - 0.00% ✗ -
Jun 12, 2024 Jun 14, 2024 Marrazzo Jeffrey D Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2024 Jun 14, 2024 Schenkein David P Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2024 Jun 14, 2024 NELSEN ROBERT Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2024 Jun 14, 2024 Kelly Michael Aaron Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2024 Jun 14, 2024 Foster-Cheek Kaye I Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2024 Jun 14, 2024 Chung Wendy Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2024 Jun 14, 2024 Cahill Thomas Director Neutral 52.5 - 0.00% ✗ -
Jun 5, 2024 Jun 7, 2024 Gottesdiener Keith Michael Officer Neutral 52.5 - 0.00% ✗ -
May 17, 2024 May 21, 2024 Reine Allan CFO Neutral 52.5 - 0.00% ✗ -
May 17, 2024 May 21, 2024 Brudnick Richard Chief Business Officer Neutral 52.5 - 0.00% ✗ -
May 17, 2024 May 21, 2024 LEE ANN L. Chief Technical Officer Neutral 52.5 - 0.00% ✗ -
Feb 29, 2024 Mar 4, 2024 Marrazzo Jeffrey D Director Neutral 52.5 - 0.00% ✗ -
Feb 25, 2024 Feb 27, 2024 Gottesdiener Keith Michael Officer Neutral 52.5 - 0.00% ✗ -
Feb 21, 2024 Feb 23, 2024 Brudnick Richard Chief Business Officer Neutral 52.5 - 0.00% ✗ -
Feb 21, 2024 Feb 23, 2024 Duffield Jeremy Chief Scientific Officer Neutral 52.5 - 0.00% ✗ -
Feb 21, 2024 Feb 23, 2024 LEE ANN L. Chief Technical Officer Neutral 52.5 - 0.00% ✗ -
Feb 21, 2024 Feb 23, 2024 Goldwasser Meredith SVP, Strategy & Corporate Ops. Neutral 52.5 - 0.00% ✗ -
Feb 21, 2024 Feb 23, 2024 Alenson Carman Officer Neutral 52.5 - 0.00% ✗ -
Feb 15, 2024 Feb 20, 2024 NELSEN ROBERT Director Buy 100.0 +3,200,000 26.07% ✗ $20M
Feb 15, 2024 Feb 20, 2024 ARCH Venture Partners XII, LLC 10% Owner Buy 100.0 +3,200,000 26.11% ✗ $20M
Feb 15, 2024 Feb 20, 2024 ARCH Venture Partners X, LLC 10% Owner Buy 100.0 +3,200,000 26.11% ✗ $20M
Jan 17, 2024 Jan 19, 2024 Reine Allan CFO Neutral 52.5 - 0.00% ✗ -
Jan 19, 2024 Reine Allan CFO Neutral 52.5 - 0.00% ✗ -
Nov 11, 2023 Nov 14, 2023 Gottesdiener Keith Michael Officer Neutral 45.0 -12,500 -0.29% ✗ -
Jul 21, 2023 Jul 26, 2023 Liu David R. 10% Owner Neutral 27.5 -1,000,000 -4.73% ✗ -
Jul 21, 2023 Jul 25, 2023 Liu David R. 10% Owner Neutral 27.5 -1,000,000 -4.73% ✗ -
Jun 14, 2023 Jun 16, 2023 Cahill Thomas Director Neutral 52.5 - 0.00% ✗ -
Jun 14, 2023 Jun 16, 2023 Schenkein David P Director Neutral 52.5 - 0.00% ✗ -
Jun 14, 2023 Jun 16, 2023 Foster-Cheek Kaye I Director Neutral 52.5 - 0.00% ✗ -
Jun 14, 2023 Jun 16, 2023 NELSEN ROBERT Director Neutral 52.5 - 0.00% ✗ -
Jun 14, 2023 Jun 16, 2023 Kelly Michael Aaron Director Neutral 52.5 - 0.00% ✗ -
Jun 14, 2023 Jun 16, 2023 Chung Wendy Director Neutral 52.5 - 0.00% ✗ -
May 10, 2023 May 12, 2023 Marrazzo Jeffrey D Director Neutral 52.5 - 0.00% ✗ -
May 12, 2023 Marrazzo Jeffrey D Director Neutral 52.5 - 0.00% ✗ -
Apr 18, 2023 Apr 20, 2023 Alenson Carman Officer Neutral 52.5 - 0.00% ✗ -
Apr 18, 2023 Apr 20, 2023 Goldwasser Meredith SVP, Strategy & Corporate Ops. Neutral 52.5 - 0.00% ✗ -
Mar 31, 2023 Apr 4, 2023 Goldwasser Meredith SVP, Strategy & Corporate Ops. Neutral 52.5 - 0.00% ✗ -
Mar 31, 2023 Apr 4, 2023 Duffield Jeremy Chief Scientific Officer Neutral 52.5 - 0.00% ✗ -
Mar 31, 2023 Apr 4, 2023 Brudnick Richard Chief Business Officer Neutral 52.5 - 0.00% ✗ -
Mar 31, 2023 Apr 4, 2023 Gottesdiener Keith Michael Officer Neutral 52.5 - 0.00% ✗ -
Mar 31, 2023 Apr 4, 2023 LEE ANN L. Chief Technical Officer Neutral 52.5 - 0.00% ✗ -
Mar 31, 2023 Apr 4, 2023 Alenson Carman Officer Neutral 52.5 - 0.00% ✗ -
Oct 24, 2022 Oct 26, 2022 ARCH Venture Partners X, LLC 10% Owner Buy 97.5 +800,000 6.98% ✗ $13.6M
Oct 24, 2022 Oct 26, 2022 NELSEN ROBERT Director Buy 97.5 +800,000 6.98% ✗ $13.6M
Oct 24, 2022 Oct 26, 2022 Liu David R. 10% Owner Neutral 52.5 - 0.00% ✗ -
Oct 24, 2022 Oct 26, 2022 Cahill Thomas Director Buy 96.3 +400,000 8.15% ✗ $6.8M
Oct 24, 2022 Oct 26, 2022 FMR LLC Other Neutral 52.5 - 0.00% ✗ -
Oct 24, 2022 NELSEN ROBERT Director Neutral 52.5 - 0.00% ✗ -
Oct 19, 2022 Oct 21, 2022 Chung Wendy Director Neutral 52.5 - 0.00% ✗ -
Oct 19, 2022 Oct 21, 2022 Foster-Cheek Kaye I Director Neutral 52.5 - 0.00% ✗ -
Oct 19, 2022 Oct 21, 2022 Kelly Michael Aaron Director Neutral 52.5 - 0.00% ✗ -
Oct 19, 2022 FMR LLC 10% Owner Neutral 52.5 - 0.00% ✗ -
Oct 19, 2022 Schenkein David P Director Neutral 52.5 - 0.00% ✗ -
Oct 19, 2022 ARCH Venture Partners X, LLC 10% Owner Neutral 52.5 - 0.00% ✗ -