2026Q1
| Insider | Role (last 12 mo) | Shares held | Filed at |
|---|---|---|---|
| Medicxi Ventures Management (Jersey) Ltd | — | 22,352,000 | Jan 6, 2025 |
| Medicxi IV GP Ltd | — | 22,352,000 | Jan 6, 2025 |
| Medicxi IV LP | — | 22,352,000 | Jan 6, 2025 |
| Medicxi Co-Invest IV LP | — | 22,352,000 | Jan 6, 2025 |
| Column Group II, Lp | 10% Owner | 3,146,989 | May 27, 2022 |
| Exec date | Filing date | Insider | Role | Signal | Confidence | Shares | % of shares | Under plan? | Amount (USD) |
|---|---|---|---|---|---|---|---|---|---|
| Mar 3, 2026 | Mar 5, 2026 | Lyons-Williams Lori | Director | Neutral | 47.5 | -4,956 | -100.00% | ✗ | - |
| Mar 3, 2026 | Mar 5, 2026 | GRAY MARY ANN | Director | Neutral | 47.5 | -4,956 | -100.00% | ✗ | - |
| Mar 3, 2026 | Mar 5, 2026 | Giordano Michael F | Director | Neutral | 47.5 | -4,956 | -100.00% | ✗ | - |
| Mar 3, 2026 | Mar 5, 2026 | Dombkowski Ashley L. | Director | Neutral | 47.5 | -4,956 | -100.00% | ✗ | - |
| Mar 3, 2026 | Mar 5, 2026 | Young Rodney KB | CFO | Neutral | 47.5 | -3,304 | -100.00% | ✗ | - |
| Mar 3, 2026 | Mar 5, 2026 | Brockstedt Dirk G. | CHIEF SCIENTIFIC OFFICER | Neutral | 47.5 | -4,648 | -100.00% | ✗ | - |
| Mar 3, 2026 | Mar 5, 2026 | Wong Brian Russell | CEO | Neutral | 47.5 | -64,102 | -100.00% | ✗ | - |
| Mar 3, 2026 | Mar 5, 2026 | Kozick Linda | Director | Neutral | 47.5 | -4,956 | -100.00% | ✗ | - |
| Mar 3, 2026 | Mar 5, 2026 | Braunstein Scott | Director | Neutral | 47.5 | -4,956 | -100.00% | ✗ | - |
| Jan 30, 2026 | Feb 2, 2026 | Braunstein Scott | Director | Neutral | 90.0 | +4,956 | 100.00% | ✗ | - |
| Jan 30, 2026 | Feb 2, 2026 | Giordano Michael F | Director | Neutral | 90.0 | +4,956 | 100.00% | ✗ | - |
| Jan 30, 2026 | Feb 2, 2026 | GRAY MARY ANN | Director | Neutral | 90.0 | +4,956 | 100.00% | ✗ | - |
| Jan 30, 2026 | Feb 2, 2026 | Lyons-Williams Lori | Director | Neutral | 90.0 | +4,956 | 100.00% | ✗ | - |
| Jan 30, 2026 | Feb 2, 2026 | Kozick Linda | Director | Neutral | 90.0 | +4,956 | 100.00% | ✗ | - |
| Jan 30, 2026 | Feb 2, 2026 | Dombkowski Ashley L. | Director | Neutral | 90.0 | +4,956 | 100.00% | ✗ | - |
| Jun 21, 2025 | Jun 30, 2025 | Dombkowski Ashley L. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 30, 2025 | Dombkowski Ashley L. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jun 21, 2025 | Jun 24, 2025 | Braunstein Scott | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 24, 2025 | Braunstein Scott | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jun 20, 2025 | Jun 24, 2025 | HO WILLIAM | CHIEF MEDICAL OFFICER | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 20, 2025 | Jun 24, 2025 | Wong Brian Russell | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 20, 2025 | Jun 24, 2025 | Young Rodney KB | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 20, 2025 | Jun 24, 2025 | Brockstedt Dirk G. | CHIEF SCIENTIFIC OFFICER | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 29, 2025 | Jun 2, 2025 | Giordano Michael F | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 29, 2025 | Jun 2, 2025 | GRAY MARY ANN | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 29, 2025 | Jun 2, 2025 | Lyons-Williams Lori | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 29, 2025 | Jun 2, 2025 | Kozick Linda | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 31, 2025 | Apr 2, 2025 | Robbins Wendye | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 31, 2025 | Apr 2, 2025 | GRAY MARY ANN | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 30, 2025 | Feb 3, 2025 | HO WILLIAM | CHIEF MEDICAL OFFICER | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 30, 2025 | Feb 3, 2025 | Young Rodney KB | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 30, 2025 | Feb 3, 2025 | Brockstedt Dirk G. | CHIEF SCIENTIFIC OFFICER | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 30, 2025 | Feb 3, 2025 | Wong Brian Russell | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 6, 2025 | Medicxi Ventures Management (Jersey) Ltd | 10% Owner | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Dec 23, 2024 | Dec 23, 2024 | COLUMN GROUP II, LP | Other | Neutral | 27.5 | -2,951,425 | -98.33% | ✗ | - |
| Dec 23, 2024 | Dec 23, 2024 | COLUMN GROUP II, LP | Other | Neutral | 27.5 | -2,951,425 | -98.33% | ✗ | - |
| Nov 13, 2024 | Nov 15, 2024 | Young Rodney KB | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 13, 2024 | Nov 15, 2024 | Wong Brian Russell | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 13, 2024 | Nov 15, 2024 | HO WILLIAM | CHIEF MEDICAL OFFICER | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 13, 2024 | Nov 15, 2024 | Brockstedt Dirk G. | CHIEF SCIENTIFIC OFFICER | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 22, 2024 | May 23, 2024 | Robbins Wendye | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 23, 2024 | May 23, 2024 | RIEFLIN WILLIAM JL | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 22, 2024 | May 23, 2024 | Lyons-Williams Lori | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 22, 2024 | May 23, 2024 | Kozick Linda | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 22, 2024 | May 23, 2024 | GRAY MARY ANN | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 22, 2024 | May 23, 2024 | Giordano Michael F | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 28, 2024 | Apr 1, 2024 | Robbins Wendye | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 28, 2024 | Apr 1, 2024 | GRAY MARY ANN | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 28, 2024 | Apr 1, 2024 | RIEFLIN WILLIAM JL | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 31, 2024 | Feb 1, 2024 | HO WILLIAM | CHIEF MEDICAL OFFICER | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 31, 2024 | Feb 1, 2024 | Young Rodney KB | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 31, 2024 | Feb 1, 2024 | Brockstedt Dirk G. | CHIEF SCIENTIFIC OFFICER | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 31, 2024 | Feb 1, 2024 | Wong Brian Russell | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 5, 2024 | Jan 8, 2024 | Brockstedt Dirk G. | CHIEF SCIENTIFIC OFFICER | Sell | 26.3 | -898 | -3.13% | ✗ | $20.5K |
| Dec 29, 2023 | Jan 2, 2024 | Brockstedt Dirk G. | Chief Scientific Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 21, 2023 | Dec 22, 2023 | HO WILLIAM | Chief Medical Officer | Sell | 25.0 | -2,500 | -14.27% | ✓ | $54.2K |
| Nov 28, 2023 | Nov 29, 2023 | HO WILLIAM | Chief Medical Officer | Sell | 32.5 | -1,500 | -7.89% | ✓ | $20.6K |
| Oct 3, 2023 | Oct 4, 2023 | HO WILLIAM | Chief Medical Officer | Sell | 28.8 | -2,500 | -11.74% | ✓ | $39.4K |
| Aug 18, 2023 | Aug 22, 2023 | HO WILLIAM | Chief Medical Officer | Sell | 28.8 | -2,500 | -10.51% | ✓ | $47.3K |
| Jul 28, 2023 | Aug 3, 2023 | HO WILLIAM | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 23, 2023 | Jun 27, 2023 | HO WILLIAM | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 24, 2023 | May 25, 2023 | Robbins Wendye | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 24, 2023 | May 25, 2023 | RIEFLIN WILLIAM JL | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 24, 2023 | May 25, 2023 | Lyons-Williams Lori | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 24, 2023 | May 25, 2023 | Kozick Linda | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 24, 2023 | May 25, 2023 | GRAY MARY ANN | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 24, 2023 | May 25, 2023 | Giordano Michael F | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 19, 2023 | Apr 20, 2023 | HO WILLIAM | Chief Medical Officer | Sell | 20.0 | -5,000 | -19.24% | ✓ | $94.4K |
| Apr 13, 2023 | Apr 14, 2023 | HO WILLIAM | Chief Medical Officer | Neutral | 58.8 | - | 0.00% | ✓ | - |
| Mar 31, 2023 | Apr 10, 2023 | RIEFLIN WILLIAM JL | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 31, 2023 | Apr 10, 2023 | Robbins Wendye | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 31, 2023 | Apr 10, 2023 | GRAY MARY ANN | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 14, 2023 | Mar 15, 2023 | Robbins Wendye | Director | Buy | 95.0 | +5,000 | 22.22% | ✗ | $97.6K |
| Mar 7, 2023 | Mar 13, 2023 | HO WILLIAM | Chief Medical Officer | Sell | 20.0 | -5,000 | -16.38% | ✓ | $148.1K |
| Mar 3, 2023 | Mar 6, 2023 | HO WILLIAM | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 31, 2023 | Feb 2, 2023 | Young Rodney KB | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 31, 2023 | Feb 2, 2023 | Wong Brian Russell | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 31, 2023 | Feb 2, 2023 | HO WILLIAM | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 31, 2023 | Feb 2, 2023 | Brockstedt Dirk G. | Chief Scientific Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 24, 2023 | Jan 26, 2023 | HO WILLIAM | Chief Medical Officer | Sell | 25.0 | -5,000 | -14.26% | ✓ | $150K |
| Jan 19, 2023 | Jan 20, 2023 | HO WILLIAM | Chief Medical Officer | Sell | 25.0 | -5,000 | -12.48% | ✓ | $127.8K |
| Jan 12, 2023 | Jan 17, 2023 | HO WILLIAM | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 5, 2023 | Jan 9, 2023 | Brockstedt Dirk G. | Chief Scientific Officer | Sell | 26.3 | -742 | -3.75% | ✗ | $16.3K |
| Dec 29, 2022 | Dec 30, 2022 | HO WILLIAM | Chief Medical Officer | Sell | 25.0 | -5,000 | -11.72% | ✓ | $90.2K |
| Nov 28, 2022 | Nov 29, 2022 | HO WILLIAM | Chief Medical Officer | Sell | 25.0 | -5,000 | -10.49% | ✓ | $89.4K |
| Nov 2, 2022 | Nov 3, 2022 | HO WILLIAM | Chief Medical Officer | Sell | 28.8 | -5,000 | -9.50% | ✓ | $111.6K |
| Oct 13, 2022 | Oct 14, 2022 | HO WILLIAM | Chief Medical Officer | Sell | 41.3 | -2,000 | -3.66% | ✓ | $43K |
| Oct 3, 2022 | Oct 4, 2022 | HO WILLIAM | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 1, 2022 | Sep 6, 2022 | HO WILLIAM | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Aug 30, 2022 | Aug 31, 2022 | HO WILLIAM | Chief Medical Officer | Sell | 37.5 | -2,500 | -4.50% | ✓ | $70.3K |
| Aug 12, 2022 | Aug 15, 2022 | HO WILLIAM | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 11, 2022 | Jul 13, 2022 | HO WILLIAM | Chief Medical Officer | Sell | 26.3 | -2,000 | -3.68% | ✗ | $39.9K |
| May 25, 2022 | May 27, 2022 | COLUMN GROUP II, LP | 10% Owner | Buy | 56.3 | +1,900 | 0.07% | ✗ | $23.7K |
| May 25, 2022 | May 27, 2022 | COLUMN GROUP II, LP | 10% Owner | Buy | 56.3 | +1,900 | 0.07% | ✗ | $23.7K |
| May 25, 2022 | May 26, 2022 | Robbins Wendye | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 25, 2022 | May 26, 2022 | RIEFLIN WILLIAM JL | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 25, 2022 | May 26, 2022 | Lyons-Williams Lori | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 25, 2022 | May 26, 2022 | Kozick Linda | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 25, 2022 | May 26, 2022 | GRAY MARY ANN | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 25, 2022 | May 26, 2022 | Giordano Michael F | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |