2026Q1
| Insider | Role (last 12 mo) | Shares held | Filed at |
|---|---|---|---|
| Orbimed Advisors Llc | Director | 708,201 | Jun 29, 2016 |
| Isaly Samuel D | Director | 708,201 | Jun 29, 2016 |
| OrbiMed Capital GP III LLC | Director | 708,201 | Jun 29, 2016 |
| Gordon Carl L | Director | 708,201 | Jun 29, 2016 |
| Singer Michael | — | 654,868 | Nov 19, 2025 |
| Exec date | Filing date | Insider | Role | Signal | Confidence | Shares | % of shares | Under plan? | Amount (USD) |
|---|---|---|---|---|---|---|---|---|---|
| Jan 6, 2026 | Jan 8, 2026 | Brunn Carsten | CEO | Sell | 42.5 | -23,766 | -6.84% | ✗ | $162.1K |
| Jan 6, 2026 | Jan 8, 2026 | Miljkovic Milos | Chief Medical Officer | Sell | 46.3 | -3,573 | -5.73% | ✗ | $24.4K |
| Jan 6, 2026 | Jan 8, 2026 | Davis Blaine | CFO | Sell | 42.5 | -10,591 | -8.03% | ✗ | $72.2K |
| Jan 2, 2026 | Jan 6, 2026 | DeSilva Nishan M | Director | Neutral | 90.0 | +2,600 | 29.66% | ✗ | - |
| Jan 2, 2026 | Jan 6, 2026 | Brunn Carsten | CEO | Neutral | 90.0 | +143,200 | 70.16% | ✗ | - |
| Jan 2, 2026 | Jan 6, 2026 | Malik Kemal | Director | Neutral | 90.0 | +2,600 | 30.47% | ✗ | - |
| Jan 2, 2026 | Jan 6, 2026 | Miljkovic Milos | Chief Medical Officer | Neutral | 90.0 | +27,000 | 76.29% | ✗ | - |
| Jan 2, 2026 | Jan 6, 2026 | ZENNER PATRICK J | Director | Neutral | 90.0 | +2,600 | 25.06% | ✗ | - |
| Jan 2, 2026 | Jan 6, 2026 | Seymour June Ann | Chief Accounting Officer | Neutral | 90.0 | +6,500 | 100.00% | ✗ | - |
| Jan 2, 2026 | Jan 6, 2026 | Davis Blaine | CFO | Neutral | 90.0 | +37,000 | 39.03% | ✗ | - |
| Jan 2, 2026 | Jan 6, 2026 | BARABE TIMOTHY C | Director | Neutral | 82.5 | +2,600 | 4.78% | ✗ | - |
| Jan 2, 2026 | Jan 6, 2026 | English Emily | Chief Operations Officer | Neutral | 90.0 | +24,000 | 34.18% | ✗ | - |
| Jan 2, 2026 | Jan 6, 2026 | Singer Michael | Director | Neutral | 60.0 | +2,600 | 0.37% | ✗ | - |
| Jan 2, 2026 | Jan 6, 2026 | SPRINGER TIMOTHY A | Director | Neutral | 47.5 | +2,600 | 0.03% | ✗ | - |
| Jan 2, 2026 | Jan 6, 2026 | Kalayoglu Murat | Director | Neutral | 55.0 | +2,600 | 0.05% | ✗ | - |
| Dec 30, 2025 | Jan 2, 2026 | English Emily | Chief Operations Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 16, 2025 | Dec 18, 2025 | Bot Adrian Ion | Director | Neutral | 90.0 | +5,800 | 100.00% | ✗ | - |
| Dec 18, 2025 | Bot Adrian Ion | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Dec 4, 2025 | Dec 8, 2025 | BARABE TIMOTHY C | Director | Buy | 95.0 | +30,000 | 123.12% | ✗ | $205.8K |
| Nov 28, 2025 | Dec 2, 2025 | English Emily | Chief Operations Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 18, 2025 | Nov 19, 2025 | Singer Michael | Director | Neutral | 27.5 | -20,000 | -2.75% | ✗ | - |
| Oct 27, 2025 | Oct 28, 2025 | Seymour June Ann | Chief Accounting Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Oct 28, 2025 | Seymour June Ann | Chief Accounting Officer | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| May 12, 2025 | May 14, 2025 | English Emily | Chief Operations Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 15, 2025 | Apr 16, 2025 | English Emily | Chief Operations Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 9, 2025 | Apr 11, 2025 | SPRINGER TIMOTHY A | Director | Buy | 87.5 | +149,075 | 1.57% | ✗ | $1.5M |
| Mar 18, 2025 | Mar 20, 2025 | SPRINGER TIMOTHY A | Director | Buy | 77.5 | +89,863 | 0.96% | ✗ | $1.4M |
| Jan 13, 2025 | Jan 15, 2025 | SPRINGER TIMOTHY A | Director | Buy | 67.5 | +20,967 | 0.22% | ✗ | $366.4K |
| Jan 10, 2025 | Jan 13, 2025 | Jewell Christopher M | Chief Scientific Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 3, 2025 | Jan 7, 2025 | Kurtoglu Metin | Chief Technology Officer | Sell | 42.5 | -4,875 | -7.26% | ✗ | $81.8K |
| Jan 3, 2025 | Jan 7, 2025 | Miljkovic Milos | Chief Medical Officer | Sell | 46.3 | -1,880 | -5.04% | ✗ | $31.5K |
| Jan 3, 2025 | Jan 7, 2025 | Jewell Christopher M | Chief Scientific Officer | Sell | 46.3 | -2,550 | -4.55% | ✗ | $42.8K |
| Jan 3, 2025 | Jan 7, 2025 | English Emily | Chief Operations Officer | Sell | 46.3 | -1,797 | -4.28% | ✗ | $30.1K |
| Jan 3, 2025 | Jan 7, 2025 | Brunn Carsten | CEO | Sell | 40.0 | -17,271 | -7.80% | ✗ | $289.8K |
| Jan 3, 2025 | Jan 7, 2025 | Davis Blaine | CFO | Sell | 42.5 | -7,989 | -7.77% | ✗ | $134K |
| Jan 2, 2025 | Jan 6, 2025 | Brunn Carsten | CEO | Neutral | 90.0 | +57,500 | 35.09% | ✗ | - |
| Jan 2, 2025 | Jan 6, 2025 | Jewell Christopher M | Chief Scientific Officer | Neutral | 90.0 | +16,100 | 40.31% | ✗ | - |
| Jan 2, 2025 | Jan 6, 2025 | English Emily | Chief Operations Officer | Neutral | 90.0 | +16,100 | 62.11% | ✗ | - |
| Jan 2, 2025 | Jan 6, 2025 | Davis Blaine | CFO | Neutral | 90.0 | +22,000 | 27.23% | ✗ | - |
| Jan 2, 2025 | Jan 6, 2025 | ZENNER PATRICK J | Director | Neutral | 90.0 | +2,600 | 33.44% | ✗ | - |
| Jan 2, 2025 | Jan 6, 2025 | Miljkovic Milos | Chief Medical Officer | Neutral | 90.0 | +19,000 | 103.98% | ✗ | - |
| Jan 2, 2025 | Jan 6, 2025 | Kalayoglu Murat | Director | Neutral | 55.0 | +2,600 | 0.05% | ✗ | - |
| Jan 2, 2025 | Jan 6, 2025 | BARABE TIMOTHY C | Director | Neutral | 90.0 | +2,600 | 11.95% | ✗ | - |
| Jan 2, 2025 | Jan 6, 2025 | SPRINGER TIMOTHY A | Director | Neutral | 47.5 | +2,600 | 0.03% | ✗ | - |
| Jan 2, 2025 | Jan 6, 2025 | Malik Kemal | Director | Neutral | 90.0 | +2,600 | 43.82% | ✗ | - |
| Jan 2, 2025 | Jan 6, 2025 | Kurtoglu Metin | Chief Technology Officer | Neutral | 90.0 | +16,100 | 31.55% | ✗ | - |
| Jan 2, 2025 | Jan 6, 2025 | Singer Michael | Director | Neutral | 60.0 | +2,600 | 0.36% | ✗ | - |
| Jan 2, 2025 | Jan 6, 2025 | COX CARRIE SMITH | Director | Neutral | 90.0 | +2,600 | 19.96% | ✗ | - |
| Jan 2, 2025 | Jan 6, 2025 | DeSilva Nishan M | Director | Neutral | 90.0 | +2,600 | 42.17% | ✗ | - |
| Dec 26, 2024 | Dec 30, 2024 | Singer Michael | Director | Neutral | 27.5 | -20,000 | -2.68% | ✗ | - |
| Dec 26, 2024 | Dec 30, 2024 | English Emily | SVP, Head of Manufacturing | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 19, 2024 | Dec 23, 2024 | SPRINGER TIMOTHY A | Director | Buy | 75.0 | +52,189 | 0.56% | ✗ | $965K |
| Dec 9, 2024 | Dec 11, 2024 | Kurtoglu Metin | Chief Technology Officer | Sell | 20.0 | -13,664 | -7.98% | ✗ | $345.1K |
| Nov 19, 2024 | Nov 21, 2024 | Kurtoglu Metin | Chief Technology Officer | Sell | 20.0 | -38,689 | -15.93% | ✗ | $649K |
| Nov 19, 2024 | Nov 21, 2024 | Singer Michael | Director | Neutral | 27.5 | -28,821 | -3.72% | ✗ | - |
| Nov 20, 2024 | Nov 21, 2024 | Jewell Christopher M | Chief Scientific Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 14, 2024 | Nov 18, 2024 | SPRINGER TIMOTHY A | Director | Buy | 93.8 | +431,940 | 4.86% | ✗ | $7.4M |
| Nov 14, 2024 | Nov 18, 2024 | Kurtoglu Metin | Chief Technology Officer | Sell | 17.5 | -82,368 | -22.93% | ✗ | $1.4M |
| Nov 14, 2024 | Nov 18, 2024 | Miljkovic Milos | Chief Medical Officer | Sell | 20.0 | -55,000 | -60.08% | ✗ | $907.5K |
| Nov 14, 2024 | Nov 18, 2024 | Jewell Christopher M | Chief Scientific Officer | Sell | 20.0 | -52,115 | -35.35% | ✗ | $875K |
| Oct 11, 2024 | Oct 15, 2024 | Kalayoglu Murat | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Oct 11, 2024 | Oct 15, 2024 | Hoge Elizabeth | 10% Owner | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Oct 2, 2024 | Oct 4, 2024 | SPRINGER TIMOTHY A | Director | Buy | 87.5 | +205,721 | 2.37% | ✗ | $4.3M |
| Sep 25, 2024 | Sep 27, 2024 | SPRINGER TIMOTHY A | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Aug 12, 2024 | Aug 14, 2024 | SPRINGER TIMOTHY A | Director | Buy | 60.0 | +8,016 | 0.13% | ✗ | $102K |
| Aug 12, 2024 | Aug 14, 2024 | BARABE TIMOTHY C | Director | Buy | 95.0 | +7,500 | 52.57% | ✗ | $95.3K |
| Jul 2, 2024 | Jul 5, 2024 | SPRINGER TIMOTHY A | Director | Neutral | 90.0 | +2,359,500 | 37.39% | ✗ | - |
| Jul 1, 2024 | Jul 3, 2024 | Malik Kemal | Director | Neutral | 90.0 | +5,933 | 100.00% | ✗ | - |
| Jul 3, 2024 | Malik Kemal | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Apr 19, 2024 | English Emily | SVP, Head of Manufacturing | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Apr 8, 2024 | Apr 10, 2024 | Singer Michael | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 8, 2024 | Apr 10, 2024 | Kalayoglu Murat | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 8, 2024 | Apr 10, 2024 | SPRINGER TIMOTHY A | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 8, 2024 | Apr 10, 2024 | Jewell Christopher M | Chief Scientific Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 8, 2024 | Apr 10, 2024 | Miljkovic Milos | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 8, 2024 | Apr 10, 2024 | Kurtoglu Metin | Chief Technology Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 8, 2024 | Apr 10, 2024 | Hoge Elizabeth | 10% Owner | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 17, 2024 | Mar 28, 2024 | SPRINGER TIMOTHY A | Director | Buy | 48.8 | +18,400 | 0.05% | ✗ | $11.4K |
| Mar 26, 2024 | Mar 26, 2024 | SPRINGER TIMOTHY A | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 18, 2024 | Mar 20, 2024 | SPRINGER TIMOTHY A | Director | Buy | 48.8 | +19,044 | 0.05% | ✗ | $11.4K |
| Mar 14, 2024 | Mar 18, 2024 | SPRINGER TIMOTHY A | Director | Buy | 90.0 | +1,185,872 | 3.17% | ✗ | $666.2K |
| Jan 2, 2024 | Jan 4, 2024 | Singer Michael | Director | Neutral | 90.0 | +178,000 | 39.79% | ✗ | - |
| Jan 2, 2024 | Jan 4, 2024 | Davis Blaine | CFO | Neutral | 90.0 | +2,424,000 | 100.00% | ✗ | - |
| Jan 2, 2024 | Jan 4, 2024 | Jewell Christopher M | Chief Scientific Officer | Neutral | 90.0 | +778,200 | 100.00% | ✗ | - |
| Jan 2, 2024 | Jan 4, 2024 | Brunn Carsten | CEO | Neutral | 90.0 | +4,654,100 | 1776.67% | ✗ | - |
| Jan 2, 2024 | Jan 4, 2024 | Sallin Aymeric | Director | Neutral | 90.0 | +178,000 | 100.00% | ✗ | - |
| Jan 2, 2024 | Jan 4, 2024 | BARABE TIMOTHY C | Director | Neutral | 90.0 | +178,000 | 71.20% | ✗ | - |
| Jan 2, 2024 | Jan 4, 2024 | SPRINGER TIMOTHY A | Director | Neutral | 60.0 | +178,000 | 0.48% | ✗ | - |
| Jan 2, 2024 | Jan 4, 2024 | Miljkovic Milos | Chief Medical Officer | Neutral | 90.0 | +548,200 | 100.00% | ✗ | - |
| Jan 2, 2024 | Jan 4, 2024 | DeSilva Nishan M | Director | Neutral | 90.0 | +178,000 | 2542.86% | ✗ | - |
| Jan 2, 2024 | Jan 4, 2024 | COX CARRIE SMITH | Director | Neutral | 90.0 | +178,000 | 83.61% | ✗ | - |
| Jan 2, 2024 | Jan 4, 2024 | ZENNER PATRICK J | Director | Neutral | 90.0 | +178,000 | 322.18% | ✗ | - |
| Jan 2, 2024 | Jan 4, 2024 | Kalayoglu Murat | Director | Neutral | 82.5 | +178,000 | 5.00% | ✗ | - |
| Jan 2, 2024 | Jan 4, 2024 | Kurtoglu Metin | COO | Neutral | 90.0 | +1,531,000 | 100.00% | ✗ | - |
| Nov 17, 2023 | Hoge Elizabeth | 10% Owner | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Nov 13, 2023 | Nov 15, 2023 | Davis Blaine | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 13, 2023 | Nov 15, 2023 | Brunn Carsten | CEO | Sell | 17.5 | -521,125 | -66.55% | ✗ | $1.1M |
| Nov 15, 2023 | Nov 15, 2023 | SPRINGER TIMOTHY A | Director | Neutral | 60.0 | +148,710 | 0.40% | ✗ | - |
| Nov 13, 2023 | Nov 15, 2023 | DeSilva Nishan M | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 13, 2023 | Nov 15, 2023 | ZENNER PATRICK J | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |