Sionna Therapeutics, Inc. (SION)

Latest Insider Confidence Score

2026Q1

37.2
Bearish

Company insider confidence (by quarter)

2025Q1 2026Q1

Largest shareholders

Insider Role (last 12 mo) Shares held Filed at
Tpg Gp A, Llc 10% Owner 6,744,962 Jul 1, 2025
Coulter James G 10% Owner 6,744,962 Jul 1, 2025
Winkelried Jon 10% Owner 6,744,962 Jul 1, 2025
Orbimed Advisors Llc Director 3,596,886 Nov 26, 2025
OrbiMed Capital GP VIII LLC Director 3,596,886 Nov 26, 2025

Recent buy/sell transactions

Exec date Filing date Insider Role Signal Confidence Shares % of shares Under plan? Amount (USD)
Mar 5, 2026 Mar 6, 2026 Fitzpatrick Jennifer Chief Legal Officer Sell 10.0 -10,250 -100.00% ✓ $347K
Feb 2, 2026 Feb 4, 2026 Thompson Peter A. Director Sell 27.5 -30,953 -0.87% ✗ $1.4M
Feb 2, 2026 Feb 4, 2026 ORBIMED ADVISORS LLC Director Sell 27.5 -30,953 -0.87% ✗ $1.4M
Jan 22, 2026 Jan 26, 2026 TPG GP A, LLC 10% Owner Sell 15.0 -250,000 -3.71% ✗ $10M
Jan 2, 2026 Jan 6, 2026 McKee Charlotte Chief Medical Officer Neutral 52.5 - 0.00% ✗ -
Jan 2, 2026 Jan 6, 2026 Fitzpatrick Jennifer Chief Legal Officer Neutral 52.5 - 0.00% ✗ -
Jan 2, 2026 Jan 6, 2026 Cloonan Michael CEO Neutral 52.5 - 0.00% ✗ -
Jan 2, 2026 Jan 6, 2026 Beer Caroline Stark Chief Business Officer Neutral 52.5 - 0.00% ✗ -
Jan 2, 2026 Jan 6, 2026 Ridloff Elena CFO Neutral 52.5 - 0.00% ✗ -
Dec 24, 2025 Dec 29, 2025 ORBIMED ADVISORS LLC Director Sell 27.5 -33,356 -0.93% ✗ $1.5M
Dec 24, 2025 Dec 29, 2025 Thompson Peter A. Director Sell 27.5 -33,356 -0.93% ✗ $1.5M
Dec 17, 2025 Dec 19, 2025 ORBIMED ADVISORS LLC Director Sell 47.5 -1,875 -0.05% ✗ $83.4K
Dec 17, 2025 Dec 19, 2025 Thompson Peter A. Director Sell 47.5 -1,875 -0.05% ✗ $83.4K
Dec 5, 2025 Dec 9, 2025 Fitzpatrick Jennifer Chief Legal Officer Sell 7.5 -10,250 -100.00% ✓ $415.3K
Nov 24, 2025 Nov 26, 2025 ORBIMED ADVISORS LLC Director Sell 17.5 -108,073 -2.92% ✗ $4.8M
Nov 24, 2025 Nov 26, 2025 Thompson Peter A. Director Sell 17.5 -108,073 -2.92% ✗ $4.8M
Nov 20, 2025 Nov 24, 2025 RA CAPITAL MANAGEMENT, L.P. Director Sell 42.5 -30,316 -0.10% ✗ $1.2M
Nov 17, 2025 Nov 19, 2025 RA CAPITAL MANAGEMENT, L.P. Director Sell 33.8 -136,351 -0.23% ✗ $5.5M
Oct 24, 2025 Oct 28, 2025 RA CAPITAL MANAGEMENT, L.P. Director Sell 15.0 -373,610 -1.82% ✗ $14.8M
Oct 21, 2025 Oct 22, 2025 Cloonan Michael CEO Sell 32.5 -99,800 -4.36% ✓ $3.6M
Oct 21, 2025 Oct 21, 2025 Booth Bruce Director Sell 36.3 -88,878 -2.88% ✓ $3M
Oct 16, 2025 Oct 20, 2025 Booth Bruce Director Sell 22.5 -286,369 -8.50% ✓ $9.3M
Oct 15, 2025 Oct 17, 2025 Cloonan Michael CEO Sell 42.5 -25,200 -1.51% ✓ $788.2K
Oct 10, 2025 Oct 15, 2025 Booth Bruce Director Sell 26.3 -194,932 -5.47% ✓ $5.9M
Oct 3, 2025 Oct 7, 2025 Booth Bruce Director Sell 40.0 -49,546 -1.37% ✓ $1.5M
Oct 1, 2025 Oct 3, 2025 Beer Caroline Stark Chief Business Officer Neutral 52.5 - 0.00% ✗ -
Oct 3, 2025 Beer Caroline Stark Chief Business Officer Neutral 52.5 - 0.00% ✗ -
Sep 29, 2025 Oct 1, 2025 Booth Bruce Director Sell 36.3 -78,693 -2.13% ✓ $2.4M
Sep 26, 2025 Sep 30, 2025 Cloonan Michael CEO Sell 38.8 -25,000 -2.23% ✓ $727.8K
Sep 4, 2025 Sep 5, 2025 Fitzpatrick Jennifer Chief Legal Officer Sell 10.0 -10,250 -100.00% ✓ $237K
Aug 29, 2025 Sep 3, 2025 Ridloff Elena CFO Sell 20.0 -9,584 -19.92% ✓ $240.4K
Aug 26, 2025 Aug 28, 2025 Cloonan Michael CEO Sell 38.8 -25,000 -2.23% ✓ $624.4K
Aug 26, 2025 Aug 28, 2025 Ridloff Elena CFO Sell 7.5 -23,416 -32.74% ✓ $601.9K
Aug 20, 2025 Aug 21, 2025 Cloonan Michael CEO Sell 35.0 -25,000 -4.37% ✓ $568.8K
Aug 19, 2025 Aug 21, 2025 Ridloff Elena CFO Sell 5.0 -52,000 -42.09% ✓ $1.1M
Jun 27, 2025 Jul 1, 2025 TPG GP A, LLC 10% Owner Buy 75.0 +60,000 0.90% ✗ $950.4K
Jun 12, 2025 Jun 16, 2025 RA CAPITAL MANAGEMENT, L.P. Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2025 Jun 16, 2025 Viney Joanne L. Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2025 Jun 16, 2025 Thompson Peter A. Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2025 Jun 16, 2025 Stelzer Laurie Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2025 Jun 16, 2025 Ruddy Marcella K. Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2025 Jun 16, 2025 Resnick Joshua Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2025 Jun 16, 2025 Fleming Harold Edward Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2025 Jun 16, 2025 Clancy Paul J Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2025 Jun 16, 2025 Booth Bruce Director Neutral 52.5 - 0.00% ✗ -
Apr 1, 2025 Fitzpatrick Jennifer Chief Legal Officer Neutral 52.5 - 0.00% ✗ -
Feb 10, 2025 Feb 12, 2025 TPG GP A, LLC 10% Owner Buy 100.0 +1,125,000 20.23% ✗ $20.3M
Feb 10, 2025 Feb 10, 2025 RA CAPITAL MANAGEMENT, L.P. Director Buy 100.0 +1,125,000 13.85% ✗ $20.3M
Feb 10, 2025 Feb 10, 2025 ORBIMED ADVISORS LLC Director Buy 100.0 +550,000 17.43% ✗ $9.9M
Feb 6, 2025 Feb 10, 2025 Ruddy Marcella K. Director Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 Feb 10, 2025 Viney Joanne L. Director Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 Feb 10, 2025 Cloonan Michael CEO Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 Feb 10, 2025 Ridloff Elena CFO Neutral 52.5 - 0.00% ✗ -
Feb 10, 2025 Feb 10, 2025 Thompson Peter A. Director Buy 100.0 +550,000 17.43% ✗ $9.9M
Feb 10, 2025 Feb 10, 2025 Booth Bruce Director Buy 95.0 +60,000 8.02% ✗ $1.1M
Feb 10, 2025 Feb 10, 2025 Atlas Venture Fund XI, L.P. 10% Owner Buy 95.0 +60,000 8.02% ✗ $1.1M
Feb 6, 2025 Feb 10, 2025 McKee Charlotte Chief Medical Officer Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 TPG GP A, LLC 10% Owner Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 Stelzer Laurie Director Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 ORBIMED ADVISORS LLC Director Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 McKee Charlotte Chief Medical Officer Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 Iancovici Lucian Director Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 Ruddy Marcella K. Director Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 Atlas Venture Fund XI, L.P. 10% Owner Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 Cloonan Michael CEO Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 RA CAPITAL MANAGEMENT, L.P. Director Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 Thompson Peter A. Director Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 Viney Joanne L. Director Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 Resnick Joshua Director Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 Fleming Harold Edward Director Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 Clancy Paul J Director Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 Ridloff Elena CFO Neutral 52.5 - 0.00% ✗ -
Feb 6, 2025 Booth Bruce Director Neutral 52.5 - 0.00% ✗ -