2026Q1
| Insider | Role (last 12 mo) | Shares held | Filed at |
|---|---|---|---|
| TCG Crossover GP II, LLC | 10% Owner | 1,274,010 | Jan 28, 2026 |
| TCG Crossover Fund II, L.P. | 10% Owner | 1,274,010 | Jan 28, 2026 |
| TCG Crossover GP III, LLC | 10% Owner | 1,274,010 | Jan 28, 2026 |
| TCG Crossover Fund III, L.P. | 10% Owner | 1,274,010 | Jan 28, 2026 |
| Consonance Capital Opportunity Fund Management LP | — | 434,000 | Dec 4, 2020 |
| Exec date | Filing date | Insider | Role | Signal | Confidence | Shares | % of shares | Under plan? | Amount (USD) |
|---|---|---|---|---|---|---|---|---|---|
| Feb 17, 2026 | Feb 18, 2026 | Li Yang | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 17, 2026 | Feb 18, 2026 | Williams Charles O | COO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 17, 2026 | Feb 18, 2026 | Parker Craig C | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 11, 2026 | Feb 13, 2026 | TCG Crossover GP II, LLC | 10% Owner | Buy | 75.0 | +18,856 | 0.73% | ✗ | $444.8K |
| Jan 30, 2026 | Feb 3, 2026 | TCG Crossover GP II, LLC | 10% Owner | Buy | 65.0 | +9,357 | 0.24% | ✗ | $202.5K |
| Jan 28, 2026 | TCG Crossover GP II, LLC | 10% Owner | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jan 23, 2026 | Jan 26, 2026 | Williams Charles O | COO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 15, 2026 | Jan 20, 2026 | COLUMN GROUP III GP, LP | 10% Owner | Buy | 85.0 | +32,507 | 1.46% | ✗ | $641.6K |
| Jan 15, 2026 | Jan 20, 2026 | Kutzkey Tim | Director | Buy | 85.0 | +32,507 | 1.46% | ✗ | $641.6K |
| Jan 13, 2026 | Jan 15, 2026 | Kutzkey Tim | Director | Buy | 75.0 | +17,993 | 0.81% | ✗ | $357.4K |
| Jan 13, 2026 | Jan 15, 2026 | COLUMN GROUP III GP, LP | 10% Owner | Buy | 75.0 | +17,993 | 0.81% | ✗ | $357.4K |
| Jan 6, 2026 | Jan 8, 2026 | COLUMN GROUP III GP, LP | 10% Owner | Buy | 75.0 | +15,100 | 0.69% | ✗ | $300.3K |
| Jan 6, 2026 | Jan 8, 2026 | Kutzkey Tim | Director | Buy | 75.0 | +15,100 | 0.69% | ✗ | $300.3K |
| Jan 2, 2026 | Jan 6, 2026 | Li Yang | President | Sell | 46.3 | -1,118 | -6.24% | ✗ | $22.2K |
| Jan 2, 2026 | Jan 6, 2026 | Williams Charles O | COO | Sell | 46.3 | -1,566 | -10.76% | ✗ | $31.1K |
| Dec 15, 2025 | Dec 16, 2025 | Li Yang | President | Neutral | 90.0 | +1,666 | 12.12% | ✗ | - |
| Dec 15, 2025 | Dec 16, 2025 | Williams Charles O | COO | Neutral | 90.0 | +1,666 | 17.76% | ✗ | - |
| Dec 15, 2025 | Dec 16, 2025 | Parker Craig C | CEO | Neutral | 90.0 | +1,553 | 22.11% | ✗ | - |
| Dec 4, 2025 | Dec 8, 2025 | Kutzkey Tim | Director | Buy | 85.0 | +36,150 | 1.67% | ✗ | $694.9K |
| Dec 4, 2025 | Dec 8, 2025 | COLUMN GROUP III GP, LP | 10% Owner | Buy | 85.0 | +36,150 | 1.67% | ✗ | $694.9K |
| Nov 13, 2025 | Dec 2, 2025 | Kutzkey Tim | Director | Buy | 100.0 | +315,457 | 17.10% | ✗ | $4M |
| Nov 13, 2025 | Nov 17, 2025 | COLUMN GROUP III GP, LP | 10% Owner | Buy | 100.0 | +315,457 | 17.10% | ✗ | $4M |
| Nov 12, 2025 | Nov 13, 2025 | Maleki Andrew Pedrum | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 13, 2025 | Maleki Andrew Pedrum | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jun 13, 2025 | Jun 16, 2025 | Li Yang | President | Neutral | 82.5 | +400 | 3.00% | ✗ | - |
| Jun 13, 2025 | Jun 16, 2025 | Williams Charles O | CFO | Neutral | 82.5 | +400 | 4.45% | ✗ | - |
| Jun 13, 2025 | Jun 16, 2025 | Parker Craig C | CEO | Neutral | 85.0 | +400 | 6.04% | ✗ | - |
| May 14, 2025 | May 15, 2025 | BJERKHOLT ERIC | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 14, 2025 | May 15, 2025 | CHAI CHRISTOPHER Y | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 14, 2025 | May 15, 2025 | Haak-Frendscho Mary | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 14, 2025 | May 15, 2025 | Rothenberg Mace | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 14, 2025 | May 15, 2025 | Lin Shao-Lee | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 14, 2025 | May 15, 2025 | WOODHOUSE DAVID J | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 14, 2025 | May 15, 2025 | Berkenblit Anna | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 1, 2025 | May 5, 2025 | Li Yang | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 1, 2025 | May 5, 2025 | Williams Charles O | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 1, 2025 | May 5, 2025 | Parker Craig C | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 26, 2025 | Mar 28, 2025 | Kutzkey Tim | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 28, 2025 | Kutzkey Tim | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 26, 2025 | Mar 28, 2025 | COLUMN GROUP III GP, LP | 10% Owner | Buy | 100.0 | +1,034,482 | 127.70% | ✗ | $12M |
| Mar 24, 2025 | Mar 25, 2025 | Williams Charles O | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 24, 2025 | Mar 25, 2025 | Parker Craig C | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 17, 2025 | Jan 22, 2025 | Parker Craig C | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 17, 2025 | Jan 22, 2025 | Li Yang | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 17, 2025 | Jan 22, 2025 | Williams Charles O | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 2, 2025 | Jan 6, 2025 | Li Yang | President | Sell | 46.3 | -843 | -5.94% | ✗ | $14.6K |
| Jan 2, 2025 | Jan 6, 2025 | Williams Charles O | CFO | Sell | 46.3 | -1,181 | -11.62% | ✗ | $20.5K |
| Jun 14, 2024 | Jun 18, 2024 | Li Yang | President | Neutral | 82.5 | +400 | 3.81% | ✗ | - |
| Jun 14, 2024 | Jun 18, 2024 | Williams Charles O | CFO | Neutral | 85.0 | +400 | 7.32% | ✗ | - |
| Jun 14, 2024 | Jun 18, 2024 | Parker Craig C | CEO | Neutral | 85.0 | +400 | 7.37% | ✗ | - |
| Jun 5, 2024 | Jun 6, 2024 | WOODHOUSE DAVID J | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2024 | Jun 6, 2024 | Lin Shao-Lee | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2024 | Jun 6, 2024 | Rothenberg Mace | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2024 | Jun 6, 2024 | Kutzkey Tim | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2024 | Jun 6, 2024 | Haak-Frendscho Mary | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2024 | Jun 6, 2024 | CHAI CHRISTOPHER Y | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2024 | Jun 6, 2024 | BJERKHOLT ERIC | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2024 | Jun 6, 2024 | Berkenblit Anna | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 1, 2024 | May 2, 2024 | Li Yang | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 1, 2024 | May 2, 2024 | Williams Charles O | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 1, 2024 | May 2, 2024 | Parker Craig C | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 24, 2024 | Apr 26, 2024 | Li Yang | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 24, 2024 | Apr 26, 2024 | Parker Craig C | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 24, 2024 | Apr 26, 2024 | Williams Charles O | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 4, 2024 | Apr 17, 2024 | COLUMN GROUP III GP, LP | 10% Owner | Buy | 100.0 | +193,548 | 45.76% | ✗ | $3M |
| Apr 4, 2024 | Apr 17, 2024 | Kutzkey Tim | Director | Buy | 100.0 | +193,548 | 45.76% | ✗ | $3M |
| Apr 4, 2024 | Apr 8, 2024 | Williams Charles O | CFO | Neutral | 90.0 | +1,474 | 100.00% | ✗ | - |
| Apr 4, 2024 | Apr 8, 2024 | Parker Craig C | CEO | Neutral | 90.0 | +1,474 | 100.00% | ✗ | - |
| Apr 4, 2024 | Apr 8, 2024 | Kutzkey Tim | Director | Buy | 100.0 | +193,548 | 44.59% | ✗ | $3M |
| Apr 4, 2024 | Apr 8, 2024 | COLUMN GROUP III GP, LP | 10% Owner | Buy | 100.0 | +193,548 | 44.59% | ✗ | $3M |
| Jan 29, 2024 | Feb 7, 2024 | Parker Craig C | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 15, 2023 | Dec 18, 2023 | Williams Charles O | CFO | Neutral | 90.0 | +2,085 | 100.00% | ✗ | - |
| Dec 15, 2023 | Dec 18, 2023 | Li Yang | President | Neutral | 90.0 | +2,085 | 100.00% | ✗ | - |
| Dec 15, 2023 | Dec 18, 2023 | Parker Craig C | CEO | Neutral | 90.0 | +2,046 | 100.00% | ✗ | - |
| Aug 23, 2023 | Li Yang | President | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jun 15, 2023 | Jun 20, 2023 | Parker Craig C | CEO | Neutral | 90.0 | +25,000 | 261.01% | ✗ | - |
| Jun 15, 2023 | Jun 20, 2023 | Yeh Wen-Chen | Chief Scientific Officer | Neutral | 90.0 | +17,638 | 184.15% | ✗ | - |
| Jun 15, 2023 | Jun 20, 2023 | Williams Charles O | CFO | Neutral | 90.0 | +25,000 | 261.01% | ✗ | - |
| May 18, 2023 | May 22, 2023 | Berkenblit Anna | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 18, 2023 | May 19, 2023 | Lin Shao-Lee | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 18, 2023 | May 19, 2023 | WOODHOUSE DAVID J | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 18, 2023 | May 19, 2023 | Rothenberg Mace | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 18, 2023 | May 19, 2023 | Kutzkey Tim | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 18, 2023 | May 19, 2023 | CHAI CHRISTOPHER Y | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 18, 2023 | May 19, 2023 | Haak-Frendscho Mary | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 18, 2023 | May 19, 2023 | BJERKHOLT ERIC | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 5, 2023 | BJERKHOLT ERIC | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 1, 2023 | Mar 2, 2023 | Parker Craig C | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 1, 2023 | Feb 2, 2023 | Williams Charles O | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 1, 2023 | Feb 2, 2023 | Yeh Wen-Chen | Chief Scientific Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 15, 2022 | Dec 19, 2022 | Yeh Wen-Chen | Chief Scientific Officer | Neutral | 82.5 | +9,578 | 4.36% | ✗ | - |
| Dec 15, 2022 | Dec 19, 2022 | Parker Craig C | CEO | Neutral | 90.0 | +9,578 | 100.00% | ✗ | - |
| Dec 15, 2022 | Dec 19, 2022 | Vanhove Geertrui | Chief Medical Officer | Neutral | 90.0 | +9,578 | 41.95% | ✗ | - |
| Dec 15, 2022 | Dec 19, 2022 | Williams Charles O | CFO | Neutral | 90.0 | +9,578 | 100.00% | ✗ | - |
| Dec 14, 2022 | Dec 15, 2022 | BLUTT MITCHELL J MD | 10% Owner | Neutral | 27.5 | -5,382,499 | -100.00% | ✗ | - |
| Oct 10, 2022 | Oct 13, 2022 | Vanhove Geertrui | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Oct 10, 2022 | Oct 13, 2022 | Williams Charles O | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Oct 10, 2022 | Oct 12, 2022 | Yeh Wen-Chen | Chief Scientific Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Oct 10, 2022 | Oct 12, 2022 | Parker Craig C | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 7, 2022 | Jun 9, 2022 | Kutzkey Tim | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |