VERTEX PHARMACEUTICALS INC / MA (VRTX)

Latest Insider Confidence Score

2026Q1

34.5
Bearish

Company insider confidence (by quarter)

2019Q1 2026Q1

Largest shareholders

Insider Role (last 12 mo) Shares held Filed at
Kewalramani Reshma CEO 115,968 Aug 7, 2025
Wagner Charles F Jr EVP, CO & FO 51,725 Dec 5, 2025
Tatsis Ourania EVP, Chief Reg. & Quality Off. 51,293 Dec 5, 2025
Arbuckle Stuart A COO 33,240 Apr 17, 2019
Bozic Carmen EVP and CMO 32,669 Feb 28, 2025

Recent buy/sell transactions

Exec date Filing date Insider Role Signal Confidence Shares % of shares Under plan? Amount (USD)
Mar 4, 2026 Mar 6, 2026 McKechnie Duncan EVP, Chief Commercial Officer Sell 23.8 -2,437 -13.88% ✓ $1.2M
Mar 2, 2026 Mar 4, 2026 Liu Joy EVP and Chief Legal Officer Sell 37.5 -892 -3.76% ✓ $442.4K
Mar 3, 2026 Liu Joy EVP and Chief Legal Officer Neutral 52.5 - 0.00% ✗ -
Feb 27, 2026 Mar 3, 2026 Kewalramani Reshma CEO Sell 7.5 -40,000 -28.93% ✓ $19.7M
Feb 27, 2026 Mar 3, 2026 Bozic Carmen EVP and CMO Sell 31.3 -2,329 -5.81% ✓ $1.1M
Feb 26, 2026 Mar 2, 2026 Ambrose Kristen SVP & Chief Accounting Officer Sell 33.8 -357 -5.11% ✓ $172.6K
Feb 24, 2026 Feb 26, 2026 WAGNER CHARLES F JR EVP, CO & FO Sell 20.0 -1,744 -3.57% ✗ $846K
Feb 24, 2026 Feb 26, 2026 Tatsis Ourania EVP, Chief Reg. & Quality Off. Sell 37.5 -1,887 -3.88% ✓ $915.7K
Feb 24, 2026 Feb 26, 2026 Sachdev Amit EVP Chief Patient & Ext Af Off Sell 36.3 -3,364 -4.87% ✓ $1.6M
Feb 24, 2026 Feb 26, 2026 McKechnie Duncan EVP, Chief Commercial Officer Sell 13.8 -5,783 -24.78% ✓ $2.8M
Feb 24, 2026 Feb 26, 2026 LEIDEN JEFFREY M Chair Sell 17.5 -3,547 -9.15% ✗ $1.7M
Feb 24, 2026 Feb 26, 2026 Kewalramani Reshma CEO Sell 17.5 -4,981 -3.48% ✗ $2.4M
Feb 24, 2026 Feb 26, 2026 Bunnage Mark E. EVP, Chief Scientific Officer Sell 25.0 -1,202 -14.16% ✓ $583.9K
Feb 24, 2026 Feb 26, 2026 Bozic Carmen EVP and CMO Sell 20.0 -1,453 -3.50% ✗ $704.9K
Feb 24, 2026 Feb 26, 2026 Biller Jonathan EVP and Chief Legal Officer Sell 23.8 -2,089 -13.27% ✓ $1M
Feb 24, 2026 Feb 26, 2026 Atkinson Edward Morrow III EVP, Chief Technical Ops. Off. Sell 23.8 -2,295 -11.07% ✓ $1.1M
Feb 24, 2026 Feb 26, 2026 Ambrose Kristen SVP & Chief Accounting Officer Sell 28.8 -769 -9.92% ✓ $373.3K
Feb 19, 2026 Feb 23, 2026 Sachdev Amit EVP Chief Patient & Ext Af Off Sell 7.5 -58,613 -45.89% ✓ $27.5M
Feb 17, 2026 Feb 19, 2026 WAGNER CHARLES F JR EVP, CO & FO Sell 100.0 +5,071 11.60% ✗ $1.1M
Feb 17, 2026 Feb 19, 2026 Tatsis Ourania EVP, Chief Reg. & Quality Off. Sell 95.0 +2,518 5.46% ✓ $1.6M
Feb 17, 2026 Feb 19, 2026 Sachdev Amit EVP Chief Patient & Ext Af Off Sell 92.5 +3,649 4.83% ✗ $1M
Feb 17, 2026 Feb 19, 2026 McKechnie Duncan EVP, Chief Commercial Officer Sell 97.5 +3,814 19.53% ✗ $555.3K
Feb 17, 2026 Feb 19, 2026 LEIDEN JEFFREY M Chair Sell 100.0 +5,305 15.85% ✗ $1.4M
Feb 17, 2026 Feb 19, 2026 Kewalramani Reshma CEO Sell 95.0 +9,772 7.32% ✗ $3.2M
Feb 17, 2026 Feb 19, 2026 Bunnage Mark E. EVP, Chief Scientific Officer Sell 13.8 -2,145 -20.18% ✓ $2.3M
Feb 17, 2026 Feb 19, 2026 Bozic Carmen EVP and CMO Sell 92.5 +3,463 9.10% ✗ $924.9K
Feb 17, 2026 Feb 19, 2026 Biller Jonathan EVP and Chief Legal Officer Sell 31.3 -1,090 -6.47% ✓ $2.5M
Feb 17, 2026 Feb 19, 2026 Atkinson Edward Morrow III EVP, Chief Technical Ops. Off. Sell 92.5 +584 2.90% ✓ $2.1M
Feb 17, 2026 Feb 19, 2026 Ambrose Kristen SVP & Chief Accounting Officer Sell 23.8 -984 -11.27% ✓ $1.4M
Feb 13, 2026 Feb 18, 2026 WAGNER CHARLES F JR EVP, CO & FO Sell 17.5 -4,565 -9.46% ✗ $2.2M
Feb 13, 2026 Feb 18, 2026 Tatsis Ourania EVP, Chief Reg. & Quality Off. Sell 23.8 -5,304 -10.31% ✓ $2.6M
Feb 13, 2026 Feb 18, 2026 Sachdev Amit EVP Chief Patient & Ext Af Off Sell 17.5 -3,548 -4.48% ✗ $1.7M
Feb 13, 2026 Feb 18, 2026 McKechnie Duncan EVP, Chief Commercial Officer Sell 17.5 -2,283 -10.47% ✗ $1.1M
Feb 13, 2026 Feb 18, 2026 Kewalramani Reshma CEO Sell 16.3 -13,041 -8.90% ✗ $6.4M
Feb 13, 2026 Feb 18, 2026 Bunnage Mark E. EVP, Chief Scientific Officer Sell 17.5 -2,283 -17.68% ✗ $1.1M
Feb 13, 2026 Feb 18, 2026 Bozic Carmen EVP and CMO Sell 17.5 -3,804 -9.09% ✗ $1.9M
Feb 13, 2026 Feb 18, 2026 Biller Jonathan EVP and Chief Legal Officer Sell 18.8 -3,981 -19.12% ✓ $2M
Feb 13, 2026 Feb 18, 2026 Bhatia Sangeeta N. Director Sell 33.8 -266 -5.83% ✓ $133K
Feb 13, 2026 Feb 18, 2026 Atkinson Edward Morrow III EVP, Chief Technical Ops. Off. Sell 20.0 -1,903 -8.63% ✗ $928.2K
Feb 13, 2026 Feb 18, 2026 Ambrose Kristen SVP & Chief Accounting Officer Sell 20.0 -1,393 -13.76% ✗ $679.4K
Feb 10, 2026 Feb 12, 2026 WAGNER CHARLES F JR EVP, CO & FO Sell 17.5 -3,045 -5.93% ✗ $1.4M
Feb 10, 2026 Feb 12, 2026 Tatsis Ourania EVP, Chief Reg. & Quality Off. Sell 36.3 -2,606 -4.82% ✓ $1.2M
Feb 10, 2026 Feb 12, 2026 Sachdev Amit EVP Chief Patient & Ext Af Off Sell 20.0 -2,057 -2.53% ✗ $963.5K
Feb 10, 2026 Feb 12, 2026 McKechnie Duncan EVP, Chief Commercial Officer Sell 20.0 -1,127 -4.91% ✗ $527.9K
Feb 10, 2026 Feb 12, 2026 Kewalramani Reshma CEO Sell 17.5 -8,297 -5.36% ✗ $3.9M
Feb 10, 2026 Feb 12, 2026 Bunnage Mark E. EVP, Chief Scientific Officer Sell 18.8 -3,148 -19.60% ✓ $1.5M
Feb 10, 2026 Feb 12, 2026 Bozic Carmen EVP and CMO Sell 17.5 -2,145 -4.87% ✗ $1M
Feb 10, 2026 Feb 12, 2026 Biller Jonathan EVP and Chief Legal Officer Sell 23.8 -3,555 -14.59% ✓ $1.6M
Feb 10, 2026 Feb 12, 2026 Atkinson Edward Morrow III EVP, Chief Technical Ops. Off. Sell 23.8 -2,623 -10.63% ✓ $1.2M
Feb 10, 2026 Feb 12, 2026 Ambrose Kristen SVP & Chief Accounting Officer Sell 20.0 -1,968 -16.27% ✓ $910.9K
Feb 3, 2026 Bunnage Mark E. EVP, Chief Scientific Officer Neutral 52.5 - 0.00% ✗ -
Jan 22, 2026 Jan 26, 2026 WAGNER CHARLES F JR EVP, CO & FO Neutral 90.0 +13,600 36.05% ✗ -
Jan 22, 2026 Jan 26, 2026 Tatsis Ourania EVP, Chief Reg. & Quality Off. Neutral 90.0 +11,749 27.78% ✗ -
Jan 22, 2026 Jan 26, 2026 Sachdev Amit EVP Chief Patient & Ext Af Off Neutral 90.0 +11,749 16.92% ✗ -
Jan 22, 2026 Jan 26, 2026 McKechnie Duncan EVP, Chief Commercial Officer Neutral 90.0 +6,800 42.14% ✗ -
Jan 22, 2026 Jan 26, 2026 LEIDEN JEFFREY M Chair Neutral 90.0 +9,012 36.83% ✗ -
Jan 22, 2026 Jan 26, 2026 Kewalramani Reshma CEO Neutral 90.0 +38,857 33.51% ✗ -
Jan 22, 2026 Jan 26, 2026 Bozic Carmen EVP and CMO Neutral 90.0 +11,333 34.69% ✗ -
Jan 22, 2026 Jan 26, 2026 Biller Jonathan EVP and Chief Legal Officer Neutral 90.0 +9,068 59.24% ✗ -
Jan 22, 2026 Jan 26, 2026 Atkinson Edward Morrow III EVP, Chief Technical Ops. Off. Neutral 90.0 +7,817 46.39% ✗ -
Jan 22, 2026 Jan 26, 2026 Ambrose Kristen SVP & Chief Accounting Officer Neutral 90.0 +4,250 54.17% ✗ -
Jan 22, 2026 Jan 26, 2026 ALTSHULER DAVID EVP, Chief Scientific Officer Neutral 90.0 +11,194 48.08% ✗ -
Jan 15, 2026 Jan 20, 2026 Upadhyay Suketu Director Neutral 52.5 - 0.00% ✗ -
Jan 15, 2026 Jan 20, 2026 SACHS BRUCE I Director Neutral 52.5 - 0.00% ✗ -
Jan 7, 2026 Jan 9, 2026 Tatsis Ourania EVP, Chief Reg. & Quality Off. Sell 27.5 -4,500 -9.62% ✓ $2.1M
Jan 6, 2026 Jan 8, 2026 WAGNER CHARLES F JR EVP, CO & FO Sell 13.8 -9,532 -20.17% ✓ $4.4M
Dec 3, 2025 Dec 5, 2025 WAGNER CHARLES F JR EVP, CO & FO Sell 3.8 -14,000 -27.07% ✓ $6.4M
Dec 3, 2025 Dec 5, 2025 Tatsis Ourania EVP, Chief Reg. & Quality Off. Sell 23.8 -4,500 -8.77% ✓ $2M
Dec 3, 2025 Dec 5, 2025 LEIDEN JEFFREY M Chair Sell 2.5 -63,781 -72.28% ✓ $28.7M
Dec 3, 2025 Dec 5, 2025 Biller Jonathan EVP and Chief Legal Officer Sell 41.3 -347 -2.22% ✓ $155.8K
Nov 19, 2025 Nov 20, 2025 CARNEY LLOYD Director Neutral 27.5 -800 -11.24% ✗ -
Nov 17, 2025 Nov 19, 2025 Atkinson Edward Morrow III EVP, Chief Technical Ops. Off. Sell 20.0 -2,500 -12.92% ✓ $1.1M
Nov 13, 2025 Nov 17, 2025 LEIDEN JEFFREY M Chair Sell 2.5 -73,292 -33.86% ✓ $32.3M
Oct 15, 2025 Oct 17, 2025 Upadhyay Suketu Director Neutral 52.5 - 0.00% ✗ -
Oct 15, 2025 Oct 17, 2025 SACHS BRUCE I Director Neutral 52.5 - 0.00% ✗ -
Oct 1, 2025 Oct 3, 2025 Biller Jonathan EVP and Chief Legal Officer Sell 22.5 -1,953 -11.09% ✓ $784.1K
Aug 27, 2025 Aug 29, 2025 Bhatia Sangeeta N. Director Sell 32.5 -266 -5.51% ✓ $102.9K
Aug 6, 2025 Aug 7, 2025 Kewalramani Reshma CEO Buy 95.0 +10,000 9.44% ✗ $3.9M
Aug 6, 2025 Aug 7, 2025 SACHS BRUCE I Director Buy 100.0 +5,000 12.50% ✗ $1.9M
Jul 15, 2025 Jul 17, 2025 Upadhyay Suketu Director Neutral 52.5 - 0.00% ✗ -
Jul 15, 2025 Jul 17, 2025 SACHS BRUCE I Director Neutral 52.5 - 0.00% ✗ -
Jul 2, 2025 McKechnie Duncan EVP, Chief Commercial Officer Neutral 52.5 - 0.00% ✗ -
Jul 1, 2025 Jul 2, 2025 Arbuckle Stuart A COO Sell 15.0 -37,243 -36.97% ✗ $16.8M
May 15, 2025 May 19, 2025 ALTSHULER DAVID EVP, Chief Scientific Officer Sell 53.8 -52 -0.22% ✓ $22.1K
May 13, 2025 May 15, 2025 Arbuckle Stuart A COO Neutral 90.0 +37,622 59.60% ✗ -
May 1, 2025 May 5, 2025 Upadhyay Suketu Director Neutral 27.5 -205 -8.01% ✗ -
May 1, 2025 May 5, 2025 Thornberry Nancy Director Neutral 90.0 +398 24.31% ✗ -
May 1, 2025 May 5, 2025 Schneider Jennifer Director Neutral 90.0 +796 86.33% ✗ -
May 1, 2025 May 5, 2025 SACHS BRUCE I Director Neutral 52.5 - 0.00% ✗ -
May 1, 2025 May 5, 2025 MCKENZIE DIANA Director Neutral 27.5 -205 -7.76% ✗ -
May 1, 2025 May 5, 2025 Lagarde Michel Director Neutral 52.5 - 0.00% ✗ -
May 1, 2025 May 5, 2025 Garber Alan M Director Neutral 85.0 +398 6.15% ✗ -
May 1, 2025 May 5, 2025 CARNEY LLOYD Director Neutral 90.0 +796 12.60% ✗ -
May 1, 2025 May 5, 2025 Bhatia Sangeeta N. Director Sell 90.0 +396 8.93% ✓ $202.3K
Apr 15, 2025 Apr 17, 2025 Upadhyay Suketu Director Neutral 52.5 - 0.00% ✗ -
Apr 15, 2025 Apr 17, 2025 SACHS BRUCE I Director Neutral 52.5 - 0.00% ✗ -
Mar 13, 2025 Mar 17, 2025 ALTSHULER DAVID EVP, Chief Scientific Officer Sell 20.0 -3,231 -12.19% ✓ $1.6M
Mar 10, 2025 Mar 12, 2025 WAGNER CHARLES F JR CFO Sell 27.5 -3,298 -6.00% ✓ $1.6M
Mar 10, 2025 Mar 12, 2025 Tatsis Ourania EVP, Chief Reg. & Quality Off. Sell 27.5 -3,242 -5.95% ✓ $1.6M
Mar 10, 2025 Mar 12, 2025 ALTSHULER DAVID EVP, Chief Scientific Officer Sell 20.0 -3,231 -10.86% ✓ $1.6M