Xilio Therapeutics, Inc. (XLO)

Latest Insider Confidence Score

2026Q1

48.5
Bearish

Company insider confidence (by quarter)

2021Q4 2026Q1

Largest shareholders

Insider Role (last 12 mo) Shares held Filed at
Gilead Sciences, Inc. — 13,335,000 Dec 1, 2025
Chudnovsky Yekaterina — 7,000,000 Sep 27, 2024
Gkcc, Llc — 7,000,000 Sep 27, 2024
Bain Capital Life Sciences Investors, LLC 10% Owner 2,805,413 Dec 10, 2021
Bain Capital Life Sciences Fund II, L.P. 10% Owner 2,805,413 Dec 10, 2021

Recent buy/sell transactions

Exec date Filing date Insider Role Signal Confidence Shares % of shares Under plan? Amount (USD)
Feb 13, 2026 Feb 17, 2026 GILEAD SCIENCES, INC. 10% Owner Neutral 52.5 - 0.00% ✗ -
Jan 1, 2026 Jan 5, 2026 Luptakova Katarina CHIEF MEDICAL OFFICER Neutral 52.5 - 0.00% ✗ -
Jan 1, 2026 Jan 5, 2026 Brennan Kevin M. SVP, FINANCE AND ACCOUNTING Sell 18.8 -1,826 -22.28% ✓ $1.2K
Jan 1, 2026 Jan 5, 2026 Frankenfield Christopher James CFO Sell 18.8 -7,030 -22.11% ✓ $4.5K
Jan 1, 2026 Jan 5, 2026 Russo Rene CEO Neutral 52.5 - 0.00% ✗ -
Nov 26, 2025 Dec 1, 2025 GILEAD SCIENCES, INC. 10% Owner Neutral 52.5 - 0.00% ✗ -
Nov 21, 2025 Nov 25, 2025 Frankenfield Christopher James CFO Neutral 52.5 - 0.00% ✗ -
Nov 21, 2025 Nov 25, 2025 Brennan Kevin M. SVP, FINANCE AND ACCOUNTING Neutral 52.5 - 0.00% ✗ -
Nov 21, 2025 Nov 25, 2025 Luptakova Katarina CHIEF MEDICAL OFFICER Neutral 52.5 - 0.00% ✗ -
Nov 21, 2025 Nov 25, 2025 Russo Rene CEO Neutral 52.5 - 0.00% ✗ -
Jun 16, 2025 Jun 18, 2025 Shannon James Samuel Director Buy 91.3 +70,000 100.00% ✗ $48.1K
Jun 16, 2025 Jun 18, 2025 Russo Rene CEO Buy 91.3 +36,289 14.82% ✗ $24.7K
Jun 18, 2025 Russo Rene CEO Neutral 52.5 - 0.00% ✗ -
Jun 11, 2025 Jun 12, 2025 ROSS ROBERT W. Director Neutral 52.5 - 0.00% ✗ -
Jun 11, 2025 Jun 12, 2025 Brennan Aoife Director Neutral 52.5 - 0.00% ✗ -
Jun 11, 2025 Jun 12, 2025 Bonstein Sara Director Neutral 52.5 - 0.00% ✗ -
Jun 11, 2025 Jun 12, 2025 Curran Daniel J. Director Neutral 52.5 - 0.00% ✗ -
Jun 11, 2025 Jun 12, 2025 Clancy Paul J Director Neutral 52.5 - 0.00% ✗ -
Jun 11, 2025 Jun 12, 2025 Xu Yuan Director Neutral 52.5 - 0.00% ✗ -
Jun 11, 2025 Jun 12, 2025 Shannon James Samuel Director Neutral 52.5 - 0.00% ✗ -
Jun 11, 2025 Jun 12, 2025 Rossi Christina Director Neutral 52.5 - 0.00% ✗ -
Jun 10, 2025 Jun 12, 2025 Bello Akintunde Olatokumbo Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2025 Bello Akintunde Olatokumbo Director Neutral 52.5 - 0.00% ✗ -
Apr 15, 2025 Apr 16, 2025 Russo Rene CEO Neutral 52.5 - 0.00% ✗ -
Apr 15, 2025 Apr 16, 2025 Frankenfield Christopher James CFO Neutral 52.5 - 0.00% ✗ -
Jan 1, 2025 Jan 3, 2025 Luptakova Katarina CHIEF MEDICAL OFFICER Neutral 52.5 - 0.00% ✗ -
Jan 1, 2025 Jan 3, 2025 Frankenfield Christopher James CFO Sell 15.0 -6,954 -35.89% ✓ $6.8K
Jan 1, 2025 Jan 3, 2025 Brennan Kevin M. SVP, FINANCE AND ACCOUNTING Sell 15.0 -1,803 -36.06% ✓ $1.8K
Jan 1, 2025 Jan 3, 2025 Russo Rene CEO Neutral 52.5 - 0.00% ✗ -
Oct 1, 2024 Oct 2, 2024 Brennan Kevin M. SVP, FINANCE AND ACCOUNTING Neutral 52.5 - 0.00% ✗ -
Sep 27, 2024 Chudnovsky Yekaterina 10% Owner Neutral 52.5 - 0.00% ✗ -
Aug 3, 2024 Aug 6, 2024 Frankenfield Christopher James COO Neutral 52.5 - 0.00% ✗ -
Jun 14, 2024 Jun 17, 2024 Xu Yuan Director Neutral 52.5 - 0.00% ✗ -
Jun 14, 2024 Jun 17, 2024 Bonstein Sara Director Neutral 52.5 - 0.00% ✗ -
Jun 14, 2024 Jun 17, 2024 ROSS ROBERT W. Director Neutral 52.5 - 0.00% ✗ -
Jun 14, 2024 Jun 17, 2024 Rossi Christina Director Neutral 52.5 - 0.00% ✗ -
Jun 14, 2024 Jun 17, 2024 Clancy Paul J Director Neutral 52.5 - 0.00% ✗ -
Jun 14, 2024 Jun 17, 2024 Curran Daniel J. Director Neutral 52.5 - 0.00% ✗ -
Jun 13, 2024 Jun 17, 2024 Shannon James Samuel Director Neutral 52.5 - 0.00% ✗ -
Jun 17, 2024 Shannon James Samuel Director Neutral 52.5 - 0.00% ✗ -
Jun 13, 2024 Jun 17, 2024 Brennan Aoife Director Neutral 52.5 - 0.00% ✗ -
Jun 17, 2024 Brennan Aoife Director Neutral 52.5 - 0.00% ✗ -
May 1, 2024 May 3, 2024 Luptakova Katarina CHIEF MEDICAL OFFICER Neutral 52.5 - 0.00% ✗ -
May 1, 2024 May 3, 2024 Brennan Kevin M. SVP, FINANCE AND ACCOUNTING Neutral 52.5 - 0.00% ✗ -
May 1, 2024 May 3, 2024 Frankenfield Christopher James COO Neutral 52.5 - 0.00% ✗ -
May 1, 2024 May 3, 2024 Russo Rene CEO Neutral 52.5 - 0.00% ✗ -
Feb 8, 2024 Feb 9, 2024 Atlas Venture Fund XI, L.P. 10% Owner Sell 52.5 -1,000 -0.04% ✗ $640
Jan 11, 2024 Jan 16, 2024 Atlas Venture Fund XI, L.P. 10% Owner Sell 52.5 -4,235 -0.15% ✗ $3.6K
Jan 1, 2024 Jan 3, 2024 Frankenfield Christopher James COO Neutral 52.5 - 0.00% ✗ -
Jan 1, 2024 Jan 3, 2024 Luptakova Katarina CHIEF MEDICAL OFFICER Neutral 52.5 - 0.00% ✗ -
Jan 1, 2024 Jan 3, 2024 Brennan Kevin M. SVP, FINANCE AND ACCOUNTING Neutral 52.5 - 0.00% ✗ -
Jan 1, 2024 Jan 3, 2024 Russo Rene CEO Neutral 52.5 - 0.00% ✗ -
Sep 5, 2023 Sep 7, 2023 Luptakova Katarina Chief Medical Officer Neutral 52.5 - 0.00% ✗ -
Sep 7, 2023 Luptakova Katarina Chief Medical Officer Neutral 52.5 - 0.00% ✗ -
Aug 16, 2023 Aug 18, 2023 Russo Rene CEO Neutral 52.5 - 0.00% ✗ -
Aug 16, 2023 Aug 18, 2023 Frankenfield Christopher James COO Neutral 52.5 - 0.00% ✗ -
Aug 16, 2023 Aug 18, 2023 Brennan Kevin M. SVP, FINANCE AND ACCOUNTING Neutral 52.5 - 0.00% ✗ -
Aug 16, 2023 Aug 18, 2023 Huber Martin H. Jr. President Neutral 52.5 - 0.00% ✗ -
Aug 3, 2023 Aug 7, 2023 Frankenfield Christopher James COO Neutral 52.5 - 0.00% ✗ -
Aug 7, 2023 Frankenfield Christopher James COO Neutral 52.5 - 0.00% ✗ -
Jun 12, 2023 Jun 13, 2023 ROSS ROBERT W. Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2023 Jun 13, 2023 Heyman Tomas J. Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2023 Jun 13, 2023 Xu Yuan Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2023 Jun 13, 2023 Bonstein Sara Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2023 Jun 13, 2023 Rossi Christina Director Neutral 52.5 - 0.00% ✗ -
Jun 12, 2023 Jun 13, 2023 Clancy Paul J Director Neutral 52.5 - 0.00% ✗ -
Apr 1, 2023 Apr 3, 2023 Brennan Kevin M. SVP, FINANCE AND ACCOUNTING Neutral 52.5 - 0.00% ✗ -
Apr 3, 2023 Brennan Kevin M. SVP, FINANCE AND ACCOUNTING Neutral 52.5 - 0.00% ✗ -
Jan 1, 2023 Jan 4, 2023 Russo Rene CEO Neutral 52.5 - 0.00% ✗ -
Jan 1, 2023 Jan 4, 2023 Huber Martin H. Jr. President Neutral 52.5 - 0.00% ✗ -
Jan 1, 2023 Jan 4, 2023 English Edward C PRINCIPAL ACCOUNTING OFFICER Neutral 52.5 - 0.00% ✗ -
Nov 16, 2022 English Edward C Principal Accounting Officer Neutral 52.5 - 0.00% ✗ -
Sep 16, 2022 Heyman Tomas J. Director Neutral 52.5 - 0.00% ✗ -
Sep 15, 2022 Sep 16, 2022 Heyman Tomas J. Director Neutral 52.5 - 0.00% ✗ -
Jun 15, 2022 Jun 23, 2022 Huber Martin H. Jr. President Neutral 52.5 - 0.00% ✗ -
Jun 15, 2022 Jun 17, 2022 Huber Martin H. Jr. President Neutral 52.5 - 0.00% ✗ -
Jun 15, 2022 Jun 17, 2022 Rossi Christina Director Neutral 52.5 - 0.00% ✗ -
Jun 15, 2022 Jun 17, 2022 Ross Michael Jay Director Neutral 52.5 - 0.00% ✗ -
Jun 15, 2022 Jun 17, 2022 Clancy Paul J Director Neutral 52.5 - 0.00% ✗ -
Jun 15, 2022 Jun 17, 2022 Xu Yuan Director Neutral 52.5 - 0.00% ✗ -
Jun 15, 2022 Jun 17, 2022 Bonstein Sara Director Neutral 52.5 - 0.00% ✗ -
Jun 15, 2022 Jun 17, 2022 ROSS ROBERT W. Director Neutral 52.5 - 0.00% ✗ -
Jun 17, 2022 ROSS ROBERT W. Director Neutral 52.5 - 0.00% ✗ -
Feb 22, 2022 Feb 24, 2022 Giovine Salvatore CFO Neutral 52.5 - 0.00% ✗ -
Feb 22, 2022 Feb 24, 2022 Huber Martin H. Jr. President Neutral 52.5 - 0.00% ✗ -
Feb 22, 2022 Feb 24, 2022 Russo Rene CEO Neutral 52.5 - 0.00% ✗ -
Jan 4, 2022 Jan 6, 2022 Xu Yuan Director Neutral 52.5 - 0.00% ✗ -
Jan 6, 2022 Xu Yuan Director Neutral 52.5 - 0.00% ✗ -
Dec 22, 2021 Jan 4, 2022 Russo Rene CEO Neutral 52.5 - 0.00% ✗ -
Dec 22, 2021 Dec 23, 2021 Russo Rene CEO Neutral 52.5 - 0.00% ✗ -
Dec 8, 2021 Dec 10, 2021 Bain Capital Life Sciences Investors, LLC 10% Owner Buy 85.0 +42,469 1.54% ✗ $410.2K
Nov 5, 2021 Bain Capital Life Sciences Investors, LLC 10% Owner Neutral 52.5 - 0.00% ✗ -
Oct 26, 2021 Nov 3, 2021 SV7 Impact Medicine Fund LP 10% Owner Buy 100.0 +625,000 24.02% ✗ $10M
Oct 26, 2021 Oct 28, 2021 Flynn James E 10% Owner Buy 100.0 +775,000 51.22% ✗ $12.4M
Oct 26, 2021 Oct 28, 2021 FIL Ltd Other Neutral 52.5 - 0.00% ✗ -
Oct 26, 2021 Oct 28, 2021 FMR LLC Other Neutral 52.5 - 0.00% ✗ -
Oct 26, 2021 Oct 28, 2021 SV7 Impact Medicine Fund LP 10% Owner Neutral 52.5 - 0.00% ✗ -
Oct 26, 2021 Oct 26, 2021 RiverVest Venture Fund IV, L.P. 10% Owner Buy 100.0 +250,000 20.98% ✗ $4M
Oct 26, 2021 Oct 26, 2021 Merck KGaA 10% Owner Neutral 52.5 - 0.00% ✗ -
Oct 26, 2021 Oct 26, 2021 Rock Springs Capital Management LP 10% Owner Buy 100.0 +500,000 66.10% ✗ $8M