Opaleye Management Inc. (CIK 0001595855)

Latest company ownership

Shares held
5,122,500
Last filed at
Apr 3, 2020
Confidence Score
50.0
2026Q1
Confidence Score History
2019Q4 2026Q1
HROW - HARROW, INC.
Role: 10% Owner
Shares held
3,815,000
Last filed at
Apr 25, 2024
Confidence Score
33.1
2026Q1
Confidence Score History
2015Q2 2026Q1
ACOG - Alpha Cognition Inc.
Role: 10% Owner
Shares held
2,193,589
Last filed at
Feb 20, 2026
Confidence Score
83.8
2026Q1
Confidence Score History
2026Q1 2026Q1
TELA - TELA Bio, Inc.
Role: 10% Owner
Shares held
2,072,813
Last filed at
Apr 20, 2023
Confidence Score
50.0
2026Q1
Confidence Score History
2022Q2 2026Q1
Shares held
378,440
Last filed at
Dec 3, 2025
Confidence Score
92.2
2026Q1
Confidence Score History
2025Q4 2026Q1
CDXS - CODEXIS, INC.
Role: 10% Owner
Shares held
179,989
Last filed at
Dec 1, 2025
Confidence Score
43.7
2026Q1
Confidence Score History
2024Q3 2026Q1
HROWM - HARROW, INC.
Role: 10% Owner
Shares held
150,000
Last filed at
Mar 4, 2025
Confidence Score
47.8
2025Q4
Confidence Score History
2025Q1 2025Q4
Shares held
85,000
Last filed at
Jun 12, 2025
Confidence Score
50.2
2026Q1
Confidence Score History
2020Q4 2026Q1
Shares held
45,000
Last filed at
Sep 12, 2024
Confidence Score
50.0
2026Q1
Confidence Score History
2020Q3 2026Q1
Shares held
15,000
Last filed at
Oct 9, 2025
Confidence Score
51.5
2026Q1
Confidence Score History
2024Q4 2026Q1

Recent buy/sell transactions

Exec date Filing date Company Role Signal Confidence Shares % of shares Under plan? Amount (USD)
Feb 20, 2026 Feb 24, 2026 Alpha Cognition Inc. 10% Owner Buy 95.0 +171,410 7.82% ✗ $1M
Feb 13, 2026 Feb 18, 2026 Sol-Gel Technologies Ltd. 10% Owner Buy 56.3 +291 0.06% ✗ $18.3K
Feb 2, 2026 Feb 18, 2026 Sol-Gel Technologies Ltd. 10% Owner Buy 47.5 +100 0.02% ✗ $5.8K
Feb 2, 2026 Feb 4, 2026 Sol-Gel Technologies Ltd. 10% Owner Buy 47.5 +100 0.02% ✗ $5.8K
Jan 27, 2026 Jan 29, 2026 Sol-Gel Technologies Ltd. 10% Owner Buy 47.5 +100 0.02% ✗ $5.7K
Jan 22, 2026 Jan 23, 2026 Sol-Gel Technologies Ltd. 10% Owner Buy 72.5 +3,324 0.73% ✗ $187.4K
Jan 6, 2026 Jan 8, 2026 HARROW, INC. 10% Owner Sell 27.5 -20,000 -0.51% ✗ $1.1M
Jan 2, 2026 Jan 6, 2026 Sol-Gel Technologies Ltd. 10% Owner Buy 72.5 +2,592 0.57% ✗ $108.9K
Dec 29, 2025 Dec 31, 2025 Sol-Gel Technologies Ltd. 10% Owner Buy 100.0 +66,304 17.11% ✗ $2.8M
Dec 22, 2025 Dec 29, 2025 Sol-Gel Technologies Ltd. 10% Owner Buy 72.5 +2,905 0.76% ✗ $120.5K
Dec 17, 2025 Dec 19, 2025 Sol-Gel Technologies Ltd. 10% Owner Buy 72.5 +2,735 0.72% ✗ $110.4K
Dec 12, 2025 Dec 16, 2025 Sol-Gel Technologies Ltd. 10% Owner Buy 47.5 +87 0.02% ✗ $3.5K
Nov 26, 2025 Dec 15, 2025 CODEXIS, INC. 10% Owner Sell 20.0 -514,341 -4.83% ✗ $877.8K
Nov 7, 2025 Dec 15, 2025 CODEXIS, INC. 10% Owner Sell 17.5 -1,063,211 -8.01% ✗ $1.9M
Dec 5, 2025 Dec 9, 2025 Sol-Gel Technologies Ltd. 10% Owner Buy 56.3 +744 0.20% ✗ $29.5K
Dec 1, 2025 Dec 3, 2025 Sol-Gel Technologies Ltd. 10% Owner Buy 85.0 +6,864 1.83% ✗ $257.6K
Nov 26, 2025 Dec 1, 2025 CODEXIS, INC. 10% Owner Sell 20.0 -217,705 -2.10% ✗ $361.3K
Nov 24, 2025 Nov 26, 2025 Sol-Gel Technologies Ltd. 10% Owner Buy 61.3 +949 0.25% ✗ $37.9K
Nov 20, 2025 Nov 21, 2025 Sol-Gel Technologies Ltd. 10% Owner Buy 82.5 +5,784 1.57% ✗ $207.2K
Nov 12, 2025 Nov 14, 2025 CODEXIS, INC. 10% Owner Buy 95.0 +697,541 7.01% ✗ $1.3M
Nov 7, 2025 Nov 12, 2025 CODEXIS, INC. 10% Owner Sell 20.0 -469,847 -3.71% ✗ $861.4K
Oct 6, 2025 Oct 9, 2025 SANUWAVE Health, Inc. 10% Owner Buy 56.3 +1,267 0.13% ✗ $38.4K
Jul 31, 2025 Aug 4, 2025 CODEXIS, INC. 10% Owner Buy 72.5 +85,000 0.67% ✗ $227.9K
Jul 29, 2025 Jul 31, 2025 CODEXIS, INC. 10% Owner Buy 56.3 +10,000 0.08% ✗ $28.2K
Jul 18, 2025 Jul 22, 2025 CODEXIS, INC. 10% Owner Buy 75.0 +100,000 0.79% ✗ $282K
Jun 27, 2025 Jul 1, 2025 CODEXIS, INC. 10% Owner Buy 72.5 +100,000 0.80% ✗ $239K
Jun 12, 2025 Jun 16, 2025 CODEXIS, INC. 10% Owner Buy 85.0 +250,000 2.04% ✗ $560K
Jun 10, 2025 Jun 12, 2025 Eton Pharmaceuticals, Inc. 10% Owner Buy 65.0 +7,930 0.28% ✗ $125.5K
Jun 9, 2025 Jun 11, 2025 HARROW, INC. 10% Owner Sell 30.0 -30,204 -0.77% ✗ $923.8K
Jun 3, 2025 Jun 5, 2025 HARROW, INC. 10% Owner Sell 47.5 -4,796 -0.12% ✗ $144K
May 23, 2025 May 28, 2025 CODEXIS, INC. 10% Owner Buy 100.0 +2,325,000 23.43% ✗ $5.5M
May 12, 2025 May 14, 2025 HARROW, INC. 10% Owner Sell 37.5 -15,000 -0.38% ✗ $391.9K
Mar 18, 2025 May 14, 2025 HARROW, INC. 10% Owner Sell 47.5 -5,000 -0.13% ✗ $148.2K
Mar 24, 2025 May 14, 2025 HARROW, INC. 10% Owner Sell 47.5 -5,000 -0.13% ✗ $150.1K
Apr 30, 2025 May 2, 2025 CODEXIS, INC. 10% Owner Buy 65.0 +45,000 0.46% ✗ $104.1K
Apr 29, 2025 Apr 30, 2025 SANUWAVE Health, Inc. 10% Owner Buy 72.5 +7,998 0.82% ✗ $203.9K
Apr 25, 2025 Apr 29, 2025 CODEXIS, INC. 10% Owner Buy 65.0 +25,000 0.25% ✗ $55.9K
Apr 15, 2025 Apr 17, 2025 CODEXIS, INC. 10% Owner Buy 85.0 +140,000 1.44% ✗ $298.8K
Apr 8, 2025 Apr 9, 2025 CODEXIS, INC. 10% Owner Buy 82.5 +100,000 1.04% ✗ $198.4K
Apr 1, 2025 Apr 3, 2025 CODEXIS, INC. 10% Owner Buy 85.0 +115,000 1.21% ✗ $271.8K
Mar 18, 2025 Mar 26, 2025 HARROW, INC. 10% Owner Sell 47.5 -5,000 -0.13% ✗ $150.1K
Mar 20, 2025 Mar 24, 2025 CODEXIS, INC. 10% Owner Buy 72.5 +92,930 0.99% ✗ $236.3K
Mar 18, 2025 Mar 20, 2025 HARROW, INC. 10% Owner Sell 47.5 -5,000 -0.13% ✗ $148.2K
Mar 13, 2025 Mar 14, 2025 CODEXIS, INC. 10% Owner Buy 72.5 +85,000 0.94% ✗ $216.2K
Mar 6, 2025 Mar 10, 2025 CODEXIS, INC. 10% Owner Buy 85.0 +100,000 1.12% ✗ $261.4K
Mar 4, 2025 Mar 6, 2025 CODEXIS, INC. 10% Owner Buy 72.5 +65,000 0.73% ✗ $172.3K
Feb 28, 2025 Mar 4, 2025 HARROW, INC. 10% Owner Sell 22.5 -5,000 -3.23% ✗ $140.3K
Feb 28, 2025 Mar 4, 2025 CODEXIS, INC. 10% Owner Buy 85.0 +195,000 2.24% ✗ $574.3K
Feb 10, 2025 Feb 12, 2025 CODEXIS, INC. 10% Owner Buy 72.5 +50,000 0.58% ✗ $205.5K
Jan 30, 2025 Jan 31, 2025 CODEXIS, INC. 10% Owner Buy 75.0 +65,000 0.76% ✗ $283K
Jan 22, 2025 Jan 24, 2025 HARROW, INC. 10% Owner Sell 20.0 -20,000 -11.43% ✗ $711.8K
Dec 30, 2024 Jan 2, 2025 CODEXIS, INC. 10% Owner Buy 72.5 +45,000 0.53% ✗ $211K
Oct 30, 2024 Nov 1, 2024 SANUWAVE Health, Inc. 10% Owner Buy 90.0 +27,868 2.95% ✗ $438.9K
Oct 25, 2024 Oct 28, 2024 CODEXIS, INC. 10% Owner Buy 65.0 +25,000 0.29% ✗ $72.7K
Oct 23, 2024 Oct 25, 2024 Eton Pharmaceuticals, Inc. 10% Owner Buy 65.0 +10,000 0.36% ✗ $79.8K
Oct 4, 2024 Oct 8, 2024 Eton Pharmaceuticals, Inc. 10% Owner Buy 85.0 +62,070 1.10% ✗ $434.1K
Sep 24, 2024 Sep 26, 2024 CODEXIS, INC. 10% Owner Buy 82.5 +85,000 1.01% ✗ $249.1K
Sep 20, 2024 Sep 23, 2024 CODEXIS, INC. 10% Owner Buy 100.0 +1,100,000 14.50% ✗ $3.3M
Sep 18, 2024 Sep 19, 2024 CODEXIS, INC. 10% Owner Buy 72.5 +61,000 0.81% ✗ $193K
Sep 11, 2024 Sep 12, 2024 Protara Therapeutics, Inc. 10% Owner Sell 20.0 -158,901 -7.40% ✗ $271.7K
Sep 10, 2024 Sep 12, 2024 Eton Pharmaceuticals, Inc. 10% Owner Buy 90.0 +107,500 4.02% ✗ $504.9K
Sep 9, 2024 Sep 10, 2024 Protara Therapeutics, Inc. 10% Owner Sell 22.5 -61,992 -2.81% ✗ $114.3K
Jul 16, 2024 Jul 18, 2024 Protara Therapeutics, Inc. 10% Owner Sell 36.3 -11,396 -0.51% ✗ $27.8K
Jul 9, 2024 Jul 11, 2024 Protara Therapeutics, Inc. 10% Owner Sell 22.5 -74,551 -3.25% ✗ $175.8K
Jul 1, 2024 Jul 3, 2024 Protara Therapeutics, Inc. 10% Owner Sell 43.8 -8,288 -0.36% ✗ $17.6K
Jun 27, 2024 Jun 28, 2024 Protara Therapeutics, Inc. 10% Owner Sell 22.5 -64,568 -2.73% ✗ $142.5K
Jun 25, 2024 Jun 27, 2024 Protara Therapeutics, Inc. 10% Owner Sell 36.3 -12,725 -0.53% ✗ $28.7K
May 30, 2024 May 31, 2024 Protara Therapeutics, Inc. 10% Owner Sell 26.3 -15,054 -12.16% ✗ $44K
May 21, 2024 May 23, 2024 Protara Therapeutics, Inc. 10% Owner Sell 32.5 -42,800 -0.88% ✗ $130.4K
May 17, 2024 May 17, 2024 Protara Therapeutics, Inc. 10% Owner Sell 22.5 -70,885 -2.82% ✗ $230.3K
May 9, 2024 May 10, 2024 Protara Therapeutics, Inc. 10% Owner Sell 20.0 -182,300 -7.11% ✗ $567K
Apr 25, 2024 Apr 25, 2024 HARROW, INC. 10% Owner Buy 72.5 +20,000 0.53% ✗ $199.4K
Apr 23, 2024 Apr 24, 2024 HARROW, INC. 10% Owner Buy 72.5 +20,000 0.53% ✗ $204.6K
Apr 19, 2024 Apr 19, 2024 HARROW, INC. 10% Owner Buy 75.0 +29,400 0.78% ✗ $310.4K
Mar 28, 2024 Mar 28, 2024 HARROW, INC. 10% Owner Buy 85.0 +50,000 1.35% ✗ $641K
Mar 20, 2024 Mar 22, 2024 HARROW, INC. 10% Owner Buy 85.0 +50,600 1.39% ✗ $488.3K
Nov 15, 2023 Nov 16, 2023 HARROW, INC. 10% Owner Buy 72.5 +25,000 0.69% ✗ $200.7K
Sep 19, 2023 Sep 20, 2023 HARROW, INC. 10% Owner Buy 75.0 +20,000 0.56% ✗ $292.1K
Dec 30, 2022 Dec 30, 2022 Protara Therapeutics, Inc. 10% Owner Buy 68.8 +15,473 0.58% ✗ $41.9K
Dec 14, 2022 Dec 14, 2022 HARROW, INC. 10% Owner Buy 100.0 +431,183 12.89% ✗ $4.5M
Nov 3, 2022 Nov 4, 2022 TELA Bio, Inc. 10% Owner Buy 72.5 +20,262 0.99% ✗ $158.3K
Oct 11, 2022 Oct 11, 2022 TELA Bio, Inc. 10% Owner Buy 72.5 +16,000 0.79% ✗ $128K
Sep 28, 2022 Sep 30, 2022 HARROW, INC. 10% Owner Buy 65.0 +11,085 0.33% ✗ $108.4K
Sep 23, 2022 Sep 26, 2022 TELA Bio, Inc. 10% Owner Buy 65.0 +6,804 0.34% ✗ $54.4K
Sep 19, 2022 Sep 19, 2022 TELA Bio, Inc. 10% Owner Buy 72.5 +18,000 0.89% ✗ $145.6K
Sep 15, 2022 Sep 16, 2022 TELA Bio, Inc. 10% Owner Buy 65.0 +6,530 0.33% ✗ $52.9K
Aug 16, 2022 Sep 15, 2022 TELA Bio, Inc. 10% Owner Buy 61.3 +5,221 0.26% ✗ $42.3K
Sep 14, 2022 Sep 15, 2022 Protara Therapeutics, Inc. 10% Owner Buy 72.5 +23,900 0.89% ✗ $93.8K
Aug 16, 2022 Aug 16, 2022 TELA Bio, Inc. 10% Owner Buy 100.0 +315,000 18.69% ✗ $2.5M
Aug 1, 2022 Aug 12, 2022 TELA Bio, Inc. 10% Owner Buy 61.3 +4,979 0.30% ✗ $39.6K
Aug 10, 2022 Aug 12, 2022 TELA Bio, Inc. 10% Owner Buy 72.5 +11,979 0.72% ✗ $102.1K
Aug 1, 2022 Aug 2, 2022 TELA Bio, Inc. 10% Owner Buy 61.3 +4,979 0.30% ✗ $39.6K
Jul 22, 2022 Jul 22, 2022 TELA Bio, Inc. 10% Owner Buy 61.3 +5,200 0.31% ✗ $41.7K
Jul 21, 2022 Jul 21, 2022 TELA Bio, Inc. 10% Owner Buy 72.5 +10,333 0.63% ✗ $83K
Jul 20, 2022 Jul 20, 2022 TELA Bio, Inc. 10% Owner Buy 61.3 +5,100 0.31% ✗ $41.2K
Jul 1, 2022 Jul 5, 2022 TELA Bio, Inc. 10% Owner Buy 60.0 +200 0.20% ✗ $1.4K
Jun 29, 2022 Jun 30, 2022 TELA Bio, Inc. 10% Owner Buy 61.3 +3,567 0.22% ✗ $25K
Jun 22, 2022 Jun 24, 2022 TELA Bio, Inc. 10% Owner Buy 56.3 +2,400 0.15% ✗ $16.8K
Jun 22, 2022 Jun 22, 2022 TELA Bio, Inc. 10% Owner Buy 90.0 +52,400 3.31% ✗ $340.6K
Jun 10, 2022 Jun 10, 2022 TELA Bio, Inc. 10% Owner Buy 82.5 +27,500 1.77% ✗ $154.1K